{"id":2254,"date":"2022-01-10T16:34:31","date_gmt":"2022-01-10T21:34:31","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/divisiontemplate\/?page_id=2254"},"modified":"2024-04-30T16:29:54","modified_gmt":"2024-04-30T20:29:54","slug":"research","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/medicine\/cardiology\/research\/","title":{"rendered":"Research"},"content":{"rendered":"

\"\"<\/a>Our goal is to increase our understanding of cardiovascular disease and thus break the cycle whereby individuals and families are impacted by death and suffering from heart and vascular disease. Through clinical trials, investigators and staff provide the mechanism for the collection of data to determine the efficacy and safety of new pharmaceuticals and devices. Trial recruitment and management is critical to the success of the program, and relies heavily on the independent work of study coordinators.<\/p>\n

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Basic Science Investigation<\/h2>\n

The UNC McAllister Heart Institute is home to many talented investigators who study various aspects of cardiovascular disease. The Institute provides a unique opportunity for basic scientists to interact with clinicians. These interactions often result in innovative research projects that provide benefits to patients now and in the future. The institute’s goals include translating\u00a0research discoveries into clinical practice, training the next generation of cardiovascular scientists, and educating local communities about advances and emerging issues in cardiovascular research.\u00a0With over 40 laboratories, research interests span across the field.<\/p>\n

Explore McAllister Heart Institute<\/a>\n<\/div>\n

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\"Fluorescent<\/p>\n<\/div>\n<\/div>\n

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Clinical Data Science<\/h2>\n

Clinical data science uses national and local databases to improve treatments, quality, outcomes and value for patients with cardiovascular disease. The ongoing development of clinical databases provides avenues for clinical research and enables cardiovascular fellows to develop the skills and a portfolio necessary to be independent cardiovascular disease researchers.<\/p>\n

Several UNC faculty are involved in clinical data science including Rick Stouffer, Matt Cavender, Joe Rossi, Patty Chang, Lindsey Rosman, Faisal Syed, Anil Gehi, Larry Klein, John Vavalle, Kevin Friede, Mirnela Byku and Lisa Rose-Jones. The shared goal of these faculty members is to better leverage observational datasets to evaluate outcomes and patterns of care, perform quality improvement, track the quality of cardiovascular care, and provide the infrastructure for population health management. This group uses national databases (e.g. NIS, SPARCS), existing quality improvement registries (e.g. NCDR and GWTG) and novel databases developed using the EPIC EHR to collect data from all the hospitals in the UNC health system. Local collaborators include the Gillings School of Public Health, the Eshelman School of Pharmacy, the North Carolina Translational and Clinical Sciences Institute, the Carolina Data Warehouse.<\/p>\n

An example of current projects includes:<\/p>\n

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