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Christine Vigeland, MD

Instructor, Division of Pulmonary Diseases and Critical Care Medicine

Specialty Areas: ARDS, interstitial lung disease

Chronology: BA: Grinnell College (2006); MD: University of Texas Southwestern Medical Center at Dallas (2010); Residency: Johns Hopkins University School of Medicine (2010-2013); Fellowship: Johns Hopkins University School of Medicine (2013-2017)

Dr. Vigeland’s lab studies lung inflammation and repair, focusing on metabolic regulation of immune responses. Her research utilizes models of acute respiratory distress syndrome (ARDS) and interstitial lung diseases. Dr. Vigeland’s clinical interests are interstitial lung diseases and critical care medicine.

Publications:

Vigeland CL, Beggs HS, Collins SL, Chan-Li Y, Powell JD, Doerschuk CM, Horton MR. Inhibition of glutamine metabolism accelerates resolution of acute lung injury. Physiological Reports 2019; 7(5): e14019. PMID: 30821123.

Vigeland CL, Hughes AH, Horton MR. Etiology and treatment of cough in idiopathic pulmonary fibrosis. Respiratory medicine. 2017; 123:98-104. PMID: 28137504.

Hallowell RW, Collins SL, Craig JM, Zhang Y, Oh M, Illei PB, Chan-Li Y, Vigeland CL, Mitzner W, Scott AL, Powell JD, Horton MR. mTORC2 Signaling Regulates M2 Macrophage Differentiation and Response to Helminth Infection and Adaptive Thermogenesis. Nat. Commun. 2017; 8, 14208. PMID: 28128208.

Vigeland CL, Horton MR. Cough in idiopathic pulmonary fibrosis: more than just a nuisance. Lancet Respir Med. 2016; 4(8):600-1. PMID: 27346585

Vigeland CL, Collins SL, Chan-Li Y, Hughes AH, Oh MH, Powell JD, Horton MR. Deletion of mTORC1 activity in T cells is associated with lung fibrosis and increased gd T cells. PLoS One. 2016; 11(9):e0163288. PMID: 27649073

Collins SL, Chan-Li Y, Oh M, Vigeland CL, Limjunyawong N, Mitzner W, Powell JD, Horton MR. Vaccinia vaccine-based immunotherapy arrests and reverses established pulmonary fibrosis. JCI Insight. 2016; 1(4):e83116. PMID: 27158671.

Vigeland CL and Horton MR. Collagen vascular disease-associated interstitial lung disease. World J of Respirol. 2015 5(2):93-101.