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Dhruti Chen, MD

Assistant Professor of Medicine, Division of Nephrology and Hypertension

Specialty Areas

Management of acute and chronic kidney diseases with a special interest in glomerulonephritis including ANCA-vasculitis, minimal change disease, other nephrotic syndromes.

Education and Experience

  • MD: University of North Carolina School of Medicine, Chapel Hill NC, 2007-2012
  • Internal Medicine Residency: Case Western Reserve University Hospitals, Cleveland OH, 2012-2015
  • Chief Resident: Case Western Reserve University, Cleveland OH, 2015-2016
  • Nephrology Research Fellowship (Nephrology), Case Western Reserve University, Cleveland OH, 2016-2017
  • Nephrology Research and Clinical Fellowship, University of North Carolina, Chapel Hill NC, 2017-2020
  • Assistant Professor of Medicine, Division of Nephrology: University of North Carolina at Chapel Hill, 2020-present.

Publications

Chen DP, Zaky Z, Schold J, Herlitz L, El-Rifai R, Drawz P, Bruggeman L, Barisoni L, Hogan S, Hu Y, O’Toole J, Poggio E, Sedor J. Podocyte Density is Reduced in Kidney Allografts with High Risk APOL1 Genotypes at Transplantation. Clin Transplant 2020 (in press)

Jones B, Herrera CA, Agosto-Burgos C, Starmer J, Bass WA, Poulton CJ, Blazek L, Henderson CD, Hu Y, Hogan SL, Hu P, Xiao X, Wu E, Chen DP, Jennette JC, Free ME, Falk RJ, Ciavatta DJ. In ANCA vasculitis, low-density neutrophils express high levels of autoantigen genes but expression in normal-density neutrophils correlates with activation by ANCA. Kidney Int Rep 2020 PubMed PMID 32446935

Chen DP, Flythe J. Dialysis-associated allergic reactions during continuous renal replacement therapy and hemodialysis: A case report. Hemodial Int. 2020 Jan; 24 (1):E5-E9. PMID 31743551. PMCID: PMC7214049.

Chen DP, Flythe JE. Dialysis-associated allertic reactions during continuous renal replacement therapy and hemodialysis: A case report. Hemodial Int 2020 Jan; 24(1):E5-9. doi: 10.1111/hdi.12801. Epub 2019 Nov 19. PubMed PMID: 31743551.

Chen DP, Davis BR, Simpson LM, Cushman WC, Cutler JA, Dobre M, Ford CE, Louis GT, Muntner P, Oparil S, Piller LB, Presser SL, Sarnak MJ, Whelton PI, Wright JT, Rahman M. Association between chronic kidney disease and cancer mortality: A report from the ALLHAT. Clin Nephrol 2017 Jan; 87(1):11-20. PubMed PMID 27900942

Humphreys BD, Xu F, Sabbisetti V, Grgic I, Movahedi Naini S, Want N, Chen G, Xiao S, Patel D, Henderson JM, Ichimura T, Mou S, Soeung S, McMahon AP, Kuchroo VK, Bonventre JV. Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. J Clin Invest 2013 Sep; 123(9):4023-35. PubMed PMID 23979159. PubMed PMCID PMC3755983

Book Chapters

Chen D, Hladik J, Falk RJ. “Glomerulonephritis.” In: Textbook of Critical Care, 8th Ed.

Chen D, Jain K. (2021) “IgA Nephropathy.” In: Ferri’s Clinical Advisor.

Chen D, Jain K. (2021) “Goodpasture Disease.” In: Ferri’s Clinical Advisor.

O’Toole JF, Chen D, Sedor JR. (2018) “Mechanisms of Glomerular Disease.” In: Trachtman H, Hogan J, Herlitz L, Lerma E (eds.). Glomerulonephritis. Springer, Cham.

 

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