Hematologic Malignancies; laboratory investigations in the role of chemokines in the development of tumor metastases
BS Magna Cum Laude: Davidson College, 1985; MS: UNC Chapel Hill, 1987; MD: Medical College of Virginia, 1993; Internal Medicine Resident: University of Michigan, 1993-1996; Chief Medical Resident: University of Michigan, 1996-1997; Hematology/Oncology Fellow: UNC Chapel Hill, 1997-2000; Instructor, Leukemia and Lymphoma Program: UNC Chapel Hill, 2000-2006; Assistant Professor: UNC Chapel Hill, 2006-2011; Clinical Associate Professor: UNC Chapel Hill, 2011-Present.
Research and Clinical Interests
In 2000, Dr. Van Deventer began a laboratory-based career with the observation that CCR5-/- mice developed fewer experimental metastases than wild-type mice. Over the course of the next 14 years, his lab focused on the mechanism behind this phenomenon. They went on to show that fibrocytes were responsible for increasing metastases. Furthermore, they substantiated our murine model by presenting data that fibrocytes promoted the progression of myeloma. He then moved on to focus on clinical research through collaborations with the School of Pharmacy. His interest has been on clinical questions that are relevant but often overlooked in larger trials. He considers his main accomplishment to be giving UNC pharmacy residents the opportunity participate in clinical research with the goal of publication.