Jen-Yea Chang, PhD

Assistant Professor of Medicine

Specialty Areas

Blood Coagulation

Chronology

PhD: University of North Carolina at Chapel Hill, 1993; Research Associate: Center for Thrombosis and Hemostasis, University of North Carolina at Chapel Hill, 1994-1998; Research Assistant Professor: University of North Carolina at Chapel Hill, 1998-present.

Research and Clinical Interests

My research focuses on blood coagulation, specifically, at factors II, V, VII, IX, X, tissue factor, and tissue factor pathway inhibitor.  By using molecular biology techniques, we are investigating the interactions between these clotting factors and their cofactors, substrates, inhibitors and cell surface receptors.  Through these studies, we hope to understand, in more detail, the mechanisms of how the hemostasis reactions are initiated, maintained and regulated.

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