M. Bradley Drummond, MD MHS

Associate Professor of Medicine, Division of Pulmonary Diseases and Critical Care Medicine
Director, Obstructive Lung Diseases Clinical and Translational Research Center

Speciality Areas: COPD, alpha-1 antitrypsin deficiency, asthma, smoking cessation, HIV-related lung diseases

Chronology: BS Biology: Emory University, 1997; MD: University of Texas Southwestern Medical School, 2001; Resident: Johns Hopkins Hospital, 2001-2004; Pulmonary and Critical Care Fellow: Johns Hopkins Hospital, 2004-2010; Chief Resident, Osler Medical Residency Program: Johns Hopkins Hospital, 2005-2006; Clinical Instructor: Johns Hopkins Hospital, 2010-2011; Assistant Professor of Medicine: Johns Hopkins Hospital, 2011-2015; Associated Professor of Medicine: Johns Hopkins Hospital, 2015-2016; Associate Professor of Medicine, University of North Carolina, 2016-Present. Director, UNC Obstructive Lung Diseases Clinical and Translational Research Center, 2016-Present.

Dr. Drummond is a board-certified pulmonary and critical care physician. His clinical expertise includes chronic obstructive lung disease (COPD), alpha-1 antitrypsin deficiency, and smoking cessation. He is also a clinical and translational researcher whose research focus includes characterizing the mechanisms for development of chronic lung disease in individuals at-risk or with chronic obstructive pulmonary disease (COPD). He has expertise in epidemiology and clinical trials design, and has applied these skills to understand the pattern and risk factors for lung function progression in smokers as well as HIV-infected individuals. His primary project is an NHLBI-funded study of a novel biomarker in the blood and lungs of individuals with or at-risk for COPD, and examining the role of vitamin D on levels of this biomarker. Additionally, Dr. Drummond is involved in characterizing the longitudinal impact of smoking, HIV infection and tobacco dependence on long-term outcomes related to chronic obstructive pulmonary disease. He is the director of the UNC Obstructive Lung Diseases Clinical and Translational Research Center, where he oversees clinical research studies supported by NIH and industry sponsors.

Selected Bibliography (reverse chronological order):

Burkes RM, Astemborski J, Lambert AA, Brown TT, Wise RA, Kirk GD, Drummond MB. Plasma cathelicidin and longitudinal lung function in current and former smokers. PLoS One. 2019 Feb 72;14(2):e0212628. PMID 30811465

Ghosh S, Pleasants RA, Ohar JA, Donohue JF, Drummond MB. Prevalence and factors associated with suboptimal peak inspiratory flow rates in COPD. International J COPD. 2019:14:585-595.

Ghosh S, Anderson WH, Putcha N, Han MK, Curtis JL, Criner GJ, Dransfield MT, Barr RG, Krishnan JA, Lazarus SC, Cooper CB, Paine R, Peters SP, Hansel NN, Martinez FJ, Drummond MB. Alignment of Inhaled COPD Therapies with Published Strategies: Analysis of the GOLD Recommendations in SPIROMICS.  Annals Am Thor Soc.2019:16(2):200-208. PMID 30216731

Pleasants RA, Wang T, Xu K, Beiko T, Bei H, Suodi Z, Drummond MB. Effect of nebulized corticosteroids on lung function in the treatment of chronic obstructive pulmonary disease exacerbations: Systematic review, meta-analysis and clinical perspective. Respiratory Care. 2018:63(10):1302-1310.

Burkes RM, Gassett AJ, Anderson W, O’Neal WK, Woodruff PG, Krishnan JA, Barr RG, Han MK, Martinez FJ, Comellas AP, Lambert AA, Kaufman JD, Dransfield MT, Wells JM, Kanner RA, Paine R, Bleecker ER, Paulin LM, Hansel NN, Drummond MB. Rural residence is associated with COPD exacerbations: Analysis of the SPIROMICS cohort. Annals Am Thor Soc.2018:15(7):808-816. PMID 29584453

Morris MA, Jacobson SR, Tashkin DP, Woodruff PG, Hoffman EA, Kanner RE, Kinnery GL, Cooper CB, Drummond MB, Barr RG, Oelner EC, Make BJ, Han MK, Hansel NN, O’Neal WK, Bowler RP. Cannabis use associations with pulmonary symptoms and function in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Chronic Obstructive Pulm Dis. 2018;5(1):46-56.

Bowler R, Hansel N, Jacobson S, Barr G, Make B, Han M, O’Neal W, Oelsner E, Casaburi R, Barjaktarevi I, Cooper C, Foreman M, Wise R, DeMeo D, Silverman E, Bailey W, Harrington K, Woodruff P, Drummond MB. Electronic cigarette use in adults at-risk or with COPD. J Gen Int Med. 2017:32(12):1315-1322. PMID 28884423

Drummond MB, Lambert AA, Hussien AF, Lin CT, Merlo CA, Wise RA, Kirk GD, Brown RH. HIV infection is independently associated with increased CT scan lung density. Acad Radiol. 2017;24:137-145. PMID 27876271

Drummond MB, Popescu I, Gama L, Lambert AA, Hoji A, Coon T, Merlo CA, Wise RA, Keruly J, Clements JE, Kirk GD, McDyer JF. HIV Suppression Restores Lung Mucosal CD4+ T-Cell Viral Immunity and Resolves CD8+ Alveolitis in Patients at Risk for HIV-associated COPD. J Infectious Diseases. 2016;214(10):1520-1530. PMID 27613775

Leader JK, Crothers K, Huang L, King MA, Morris A, Thompson BW, Flores SC, Drummond MB, Rom WN, Diaz PT. Risk Factors Associated With Quantitative Evidence of Lung Emphysema and Fibrosis in an HIV-Infected Cohort. J Acquir Immune Defic Syndr. 2016:71:420-427.

Drummond MB, Huang L, Diaz PT, Kirk GD, Kleerup EC, Morris A, Rom W, Weiden MD, Zhao E, Thompson B, Crothers K. Factors associated with abnormal spirometry among HIV-infected individuals. AIDS. 2015;29(13):1691-1700.

Brown RH, Wise RA, Kirk G, Drummond MB, Mitzner W. Lung density changes with growth and inflation. Chest. 2015;148(4):995-1002.

Lambert AA, Kirk GD, Astemborski J, Mehta SH, Wise RA, Drummond MB. HIV Infection is Associated with Increased Risk for Acute Exacerbation of COPD. JAIDS. 2015;69(1):68-74.

Drummond MB, Popescu I, Gama L, Coon T, Merlo CA, Wise RA, Clements JE, Kirk GD, McDyer JF. Activation-induced cell death drives profound lung CD4+ T cell depletion in HIV-associated COPD. Am J Resp Crit Care Med. 2014;190(7):744-755.

Drummond MB, Astemborski J, Lambert AA, Goldberg S, Stitzer ML, Merlo CA, Rand CS, Wise RA, Kirk GD. A Randomized Study of Contingency Management and Spirometric Lung Age for Motivating Smoking Cessation among Injection Drug Users. BMC Public Health. 2014;14:761.

Lambert AA, Drummond MB, Mehta SH, Brown TT, Lucas GM, Kirk GD, Estrella MM. Risk Factors for Vitamin D Deficiency among HIV-infected and Uninfected Injection Drug Users. PLoSOne. 2014;9(4):e95802.

Lambert AA, Kirk GD, Astemborski J, Neptune ER, Mehta SH, Wise RA, Drummond MB. A cross sectional analysis of the role of the antimicrobial peptide cathelicidin in lung function impairment with the ALIVE cohort. PLoSOne. 2014;9(4):e95099.

Putcha N, Drummond MB, Connett JE, Scanlon PD, Tashkin DP, Hansel NN, Wise RA. Chronic productive cough is associated with death in smokers with early COPD. COPD. 2014;11(4):451-458.

Fischer WA, Drummond MB, Merlo CA, Thomas DL, Brown R, Mehta SH, Wise RA, Kirk GD. Hepatitis C infection is not an independent risk factor for obstructive lung disease. COPD. 2014;11(1):10-16.

Drummond MB, Merlo CA, Astemborski J, Kalmin MM, Kisalu A, McDyer JF, Mehta SH, Brown RH, Wise R, Kirk GK. The effect of HIV infection on longitudinal lung function decline among injection drug users: A prospective cohort. AIDS. 2013;27(8):1303-1311.

Putcha N, Puhan MA, Hansel NN, Drummond MB, Boyd CM. Impact of comorbidities on self-rated health in self-reported COPD: an analysis of NHANES 2001-2008. J COPD. 2013;10(3):324-332.

Drummond MB, Hansel NH, Connett JE, Scanlon PD, Tashkin DP, Wise RA. Spirometric predictors of lung function decline and mortality in early COPD. Am J Respir Crit Care Med. 2012;185(12):1301-1306.

Drummond MB, Kirk GD, Astemborksi J, Marshall MM, Mehta SH, McDyer JF, Brown RH, Wise RA and Merlo CA. Association between obstructive lung disease and markers of HIV infection in a high risk cohort. Thorax. 2012;67:309-314.

Drummond MB, Peters SP, Castro M, Holbrook JT, Irvin CG, Smith LJ, Wise RA and Sugar EA. Risk factors for montelukast treatment failure in step-down therapy for controlled asthma. Journal of Asthma. 2011;48:1051-1057.

Drummond MB, Kirk GD, Astemborski J, McCormack MC, Marshall MM, Mehta SH, Wise RA, Merlo CA. Prevalence and risk factors for unrecognized obstructive lung disease among urban drug users. Int J Chron Obstruct Pulmon Dis. 2011;6:89-95.

Drummond MB, Kirk GD, McCormack MC, Marshall MM, Ricketts EP, Mehta SH, Wise RA, Merlo CA. HIV and COPD: impact of risk behaviors and diseases on quality of life. Qual Life Res. 2010;19(9):1295-1302.

Drummond MB, Wise RA, John M, Zvarich MT, McGarvey LP. Accuracy of death certificates in COPD: analysis from the TORCH trial. COPD. 2010;7(3):179-185.

Drummond MB, Kirk GD, Ricketts EP, McCormack MC, Hague JC, McDyer JF, Mehta SH, Engels EA, Wise RA, Merlo CA. Cross sectional analysis of respiratory symptoms in an injection drug user cohort: the impact of obstructive lung disease and HIV. BMC Pulm Med. 2010; 10:27.

Drummond MB, Dasenbrook EC, Pitz MW, Murphy DJ, Fan E. Inhaled corticosteroids in patients with stable chronic obstructive pulmonary disease. JAMA. 2008;300(20):2407-2416.

Drummond MB, Blackford AL, Benditt JO, Make BJ, Sciurba FC, McCormack MC, Martinez FJ, Fessler HE, Fishman AP, Wise RA; NETT Investigators. Continuous oxygen use in nonhypoxemic emphysema patients identifies a high-risk subset of patients: retrospective analysis of the National Emphysema Treatment Trial. Chest. 2008;134(3):497-506.

Drummond MB, Schwartz PF, Duggan WT, Teeter JG, Riese RJ, Ahrens RC, Crapo RO, England RD, Macintyre NR, Jensen RL, Wise RA. Intersession variability in single-breath diffusing capacity in diabetics without overt lung disease. Am J Respir Crit Care Med. 2008;178(3):225-232.

 

A complete list of Dr. Drummond’s publications can be found here.

 

 

bradley-drummond