Nicholas J. Talley, MD, PhD

Adjunct Professor of Medicine, Division of Gastroenterology and Hepatology

Laureate Professor Nick Talley is currently Pro Vice-Chancellor, Global Research at the University of Newcastle, Australia. He is an expert clinician, educator and researcher, with extensive experience as a leader in the medical and University sectors. He previously held an appointment as Pro Vice-Chancellor (and Dean) of the Faculty of Health and Medicine at the University of Newcastle from 2010-2015, and was seconded to be the Deputy Vice-Chancellor-Research (Acting) at the University of Newcastle from June 2013 to March 2014.

Professor Talley is a neurogastroenterologist, has published over 1000 papers in the peer-reviewed literature, and is considered one of the world’s most influential clinician-researchers (H index 130, Scopus 2018). He is the Editor-in-Chief of the Medical Journal of Australia (since 2015). He is also a leading medical educator and the author of the highly regarded textbooks Clinical Examination and Examination Medicine. In June 2014, Professor Talley was inaugurated as one of the first 15 Fellows of the Australian Academy of Health and Medical Sciences (FAHMS) and was elected to the Executive of the Academy.

Education and Training

Degree Institution Area
MB, BS (Hons) University of NSW, Australia Medicine
PhD University of Sydney, Australia Medicine
MD University of NSW, Australia Medicine (Research)
(Clin Epi)
University of Newcastle, Australia Epidemiology (molecular and genetic)

Selected Bibliography:

  1. Talley NJ, Vakil N, Ballard ED and Fennerty MB. Absence of benefit of eradicating Helicobacter pylori in patients with non-ulcer dyspepsia. New England Journal of Medicine 1999;341:1106-11.
  2. Ronkainen J, Talley NJ, Aro P, Storskrubb T, Johansson SE, Lind T, Bolling-Sternevald E, Vieth M, Stolte M, Walker MM, Agreus L. Prevalence of oesophageal eosinophils and eosinophilic oesophagitis in adults: The population-based Kalixanda study. Gut. 2007; 56:615-20
  3. Walker MM, Talley NJ, Prabhakar M, Pennaneac’h CJ, Aro P, Ronkainen J, Storskrubb T, Harmsen WS, Zinsmeister AR, Agreus L. Duodenal mastocytosis, eosinophilia and intra-epithelial lymphocytosis as possible disease markers in the irritable bowel syndrome and functional dyspepsia. Aliment Pharmacol Ther. 2009; 29:765-73
  4. Walker MM, Murray JA, Ronkainen J, Aro P, Storskrubb T, D’Amato M, Lahr B, Talley NJ, Agreus L. Detection of Celiac Disease and Lymphocytic Enteropathy by Parallel Serology and Histopathology in a Population-Based Study. Gastroenterology. 2010; 139:112-9
  5. Liebregts T, Adam B, Bredack C, Gururatsakul M, Pilkington K, Brierley S, Blackshaw A, Gerken G, Talley NJ, Holtmann G. Small bowel homing T cells are associated with symptoms and delayed gastric emptying in functional dyspepsia. Am J Gastroenterol 2011; 106:1089.
  6. Holtmann G, Talley NJ, Liebregts T, Adam B, Parow C. A placebo-controlled trial of itopride in functional dyspepsia. New England Journal of Medicine 2006;354:832-40.
  7. Liebregts T, Adam B, Bredack C, Röth A, Heinzel S, Lester S, Downie-Doyle S, Smith E, Drew P, Talley NJ, Holtmann G. Immune activation in patients with irritable bowel syndrome. Gastroenterology. 2007: 132:913-20.
  8. Talley NJ, Abreu MT, Achkar JP, Bernstein CN, Dubinsky MC, Hanauer SB, Kane SV, Sandborn WJ, Ullman, TA, Moayyedi, P for the American College of Gastroenterology IBD Task Force. An Evidence-Based Systematic Review on Medical Therapies for Inflammatory Bowel Disease. Am J Gastroenterol 2011; 106:S2–S25; doi:10.1038/ajg.2011.58.
  9. Talley NJ, Locke GR, Saito YA, Almazar AE, Bouras EP, Howden CW, Lacy BE, DiBaise JK, Prather CM, Abraham BP, El-Serag HB, Moayyedi P, Herrick LM, Szarka LA, Camilleri M, Hamilton FA, Schleck CD, Tilkes KE, Zinsmeister AR. Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study. Gastroenterology. 2015;149:340-9.
  10. Talley, NJ, Ford, A. Functional Dyspepsia. N Engl J Med. 2015;373:1853-63.