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Paul Michael Armistead MD, PhD

Associate Professor of Medicine, Division of Hematology

Specialty Areas

Hematopoietic stem cell transplant; Hematologic malignancies; Leukemia antigen discovery; Minor histocompatibility antigens; Cancer immunology; Leukemia minimal residual disease quantification; Single cell analysis.


BS Chemistry: University of North Carolina, 1995; PhD Chemistry: University of North Carolina, 1997-2000; MD: University of North Carolina, 1995-1997, 2000-2002; Intern and Resident: Brigham and Women’s Hospital, Boston MA 2002-2005; Fellowship in Hematology / Oncology: University of Texas, M.D. Anderson Cancer Center, Houston TX 2005-2008; Rattay Advanced Fellows Instructorship in Stem Cell Transplant / Cancer Immunology: University of Texas, M.D. Anderson Cancer Center, Houston TX 2008-2009; Assistant Professor of Medicine: University of North Carolina, 2009-2017; Associate Professor of Medicine: University of North Carolina 2017-present.

Research and Clinical Interests

Dr. Armistead’s clinical interests focus on hematopoietic stem cell transplant to treat leukemia, lymphoma and multiple myeloma. This focus coincides with his research interests that focus on immune responses to hematologic malignancies and the discovery of tumor antigens for the development of immunotherapeutics.

Personal Statement

I thoroughly enjoy my work in the UNC Bone Marrow Transplant and Cellular Therapy Program. My clinical work allows me to treat patients with many forms of blood cancers, and it is gratifying to be able to provide therapies that can prolong life, and in some cases, cure patients from highly aggressive leukemias and lymphomas. Because of the side-effects associated with transplantation, my research interests focus on developing other immunology-based therapies so that we can provide curative therapies to patients with these diseases without the toxicity.

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