Assistant Professor of Medicine
Medical Director, UNC Rheumatology Clinic
Director, UNC Rheumatology Fellowship Program
Specialty Areas: general rheumatology, evaluating and managing inflammatory arthritis, medical education
Chronology: ScB with Honors and Magna Cum Laude: Brown University, 1996; PhD in Microbiology: Graduate School of Arts and Sciences, University of Virginia, 2004; MD: School of Medicine, University of Virginia, 2005; Internal Medicine Resident: Brigham and Women’s Hospital, 2005-2008; Rheumatology Fellow: Brigham and Women’s Hospital, 2008-2011; Associate Clinician: Brigham and Women’s Hospital, 2011-2015; Instructor in Medicine: Harvard University, 2011-2015; Clinical Assistant Professor of Medicine: University of North Carolina, 2015-present
Description of research and/or clinical interests: Dr. Ishizawar’s clinical interests focus on inflammatory arthritis such as rheumatoid arthritis and seronegative spondyloarthritis. She has participated in functional genomic research in rheumatoid arthritis. She is focused on providing exceptional care to patients with rheumatologic conditions at the UNCH Rheumatology Specialty Clinic at Carolina Pointe II, and is involved in medical education at the University of North Carolina as well as through the American College of Rheumatology.
Shrinking lung syndrome as a manifestation of pleuritis: a new model based on pulmonary physiological studies. Henderson LA, Loring SH, Gill RR, Liao KP, Ishizawar R, Kim S, Perlmutter-Goldenson R, Rothman D, Son MB, Stoll ML, Zemel LS, Sandborg C, Dellaripa PF, Nigrovic PA. J Rheumatol. 2013 Mar;40(3):273-81. doi: 10.3899/jrheum.121048. Epub 2013 Feb 1. PMID: 23378468
Full facial edema: a novel presentation of subcutaneous panniculitis-like T-cell lymphoma. Velez NF, Ishizawar RC, Dellaripa PF, Saavedra AP, Laga AC, Murphy GF, Fisher DC, Kupper TS, Vleugels RA. J Clin Oncol. 2012 Sep 1;30(25):e233-6. doi: 10.1200/JCO.2011.40.7684. Epub 2012 Jul 23. No abstract available. PMID: 22826278
Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation. Simarro M, Giannattasio G, De la Fuente MA, Benarafa C, Subramanian KK, Ishizawar R, Balestrieri B, Andersson EM, Luo HR, Orduña A, Boyce J, Anderson P. J Immunol. 2010 May 1;184(9):5325-32. doi: 10.4049/jimmunol.1000104. Epub 2010 Apr 2. PMID: 2036397
c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function. Ishizawar RC, Miyake T, Parsons SJ. Oncogene. 2007 May 24;26(24):3503-10. Epub 2006 Dec 18. PMID: 17173075
c-Src and cooperating partners in human cancer. Ishizawar R, Parsons SJ. Cancer Cell. 2004 Sep;6(3):209-14. Review.
The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism. Ishizawar RC, Tice DA, Karaoli T, Parsons SJ. J Biol Chem. 2004 May 28;279(22):23773-81. Epub 2004 Mar 18. PMID: 15031291
Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer. Biscardi JS, Ishizawar RC, Silva CM, Parsons SJ. Breast Cancer Res. 2000;2(3):203-10. Epub 2000 Mar 7. Review. PMID: 11250711