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Samuel Cykert, MD

Professor, Division of General Medicine and Clinical Epdemiology
Director, UNC School of Medicine Program on Health and Clinical Informatics
Associate Director for Medical Education, NC AHEC Program
Clinician and Researcher

Specialty Areas: Chronic Disease Management; Interventions to Reduce Racial Disparities in Healthcare

Chronology: BS with highest distinction: Valapraiso University, 1977; MD with highest distinction: Indiana University School of Medicine, 1983; Private Practice in Burlington, NC, 1986-1992; Internal Medicine Training Program, 1992–2010; (1995-2002, University based faculty, Assistant Professor-Tenure Track) Moses H. Cone Memorial Hospital, Greensboro, NC (affiliated with the University of North Carolina at Chapel Hill); Associate Program Director, Internal Medicine Program, Moses Cone Memorial Hospital, 1997-2003; Faculty, University of North Carolina General Internal Medicine Faculty Development Fellowship, Director of Research Component, 1999-2010; Associate Professor, UNC School of Medicine, 2002-2011; Chief and Program Director, Internal Medicine Program, Moses Cone Memorial Hospital, 2003-2006 and 2008-2010; Chief, Internal Medicine Program, Moses Cone Memorial Hospital, 2003-2008; Professor, UNC School of Medicine, 2011-present; Associate Director for Medical Education, NC AHEC Program, 2010-Present; Director, the University of North Carolina Program for Health and Clinical Informatics, 2013-Present; Adjunct Professor of Health Policy and Management, Gillings School of Global Public Health, 2014-Present.

Dr. Cykert’s research interests include rapid dissemination and implementation of new evidence across community practices, enhancing chronic care management including techniques involving community outreach, and interventions to reduce racial disparities in health and healthcare.

Selected Bibliography:

Cykert S, Eng E, Manning M, Robertson L, Heron D, Jones N, Schaal J, Zhou H, Yongue C, Gizlice Z. A Multi-Faceted Intervention Aimed at Black-White Disparities in the Treatment of Early Stage Cancers: The ACCURE Pragmatic Trial. J Natl Med Assoc. 2019 Mar 27. pii: S0027-9684(18)30191-3. doi: 10.1016/j.jnma.2019.03.001.

Gang Fang, Izabela E Annis, Jennifer Elston-Lafata, Samuel Cykert. Applying Machine Learning to Predict Real-World Individual Treatment Effects – Insights from a Virtual Patient Cohort. Journal of the American Medical Informatics Association. 2019. ocz036,

Cykert S, Eng E, Walker P, Manning M, Robertson L, Arya R, Jones N, Heron D. A system‐based intervention to reduce Black‐White disparities in the treatment of early stage lung cancer: A pragmatic trial at five cancer centers. Cancer Med. 2019;00:1–8.

Cykert S., DeWalt D., Weiner B., Pignone M. A Population Approach Using Cholesterol Imputation to Identify Adults with High Cardiovascular Risk: A Report from North Carolina on AHRQ’s EvidenceNow Initiative. J Am Med Inform Assoc. 2018 Nov 29. doi: 10.1093/jamia/ocy151

Samuel, C.A., Schaal, J., Robertson, L., Kollie, J., Baker, S., Black, K., Mbah, O., Dixon, C., Ellis, K., Eng, E., Guerrab, F., Jones, N., Kotey, A., Morse, C., Taylor, J., Whitt, V., Cykert, S. Racial differences in symptom management during breast cancer treatment. Supportive Care in Cancer 2018 May;26(5):1425-1435 .

Weiner B, Pignone M, DuBard C., Lefebvre A, Suttie J, Freburger J, Cykert S. Advancing heart health in North Carolina primary care: the Heart Health NOW study protocol. Implementation Science Implementation Science 2015;10:160.

Carey T., Donahue K., Halladay J., and Cykert S. Practice Based Research Networks in the Era of Integrated Delivery Systems. Journal of the American Board of Family Medicine 2015;28:658-662.

Cykert S, Walker PR, Edwards LJ, McGuire FR, Dilworth-Anderson P. Weighing projections of physical decline in lung cancer surgery decisions. Am J Med Sci. 2015;349:61-66.

Cykert S. A New Paradigm: Approaching Racism as a Method of Disease Prevention. Chest 2014;145 (3):442-443.

Cykert S, Dilworth-Anderson P, Monroe MH, Walker P,McGuire FR, Corbie-Smith G, Edwards LJ, Bunton AJ. Modifiable factors associated with decisions to undergo surgery among newly diagnosed patients with early stage lung cancer. JAMA 2010; 303(23): 2368-2376.

News article:
The New York Times – Prognosis: When Cancer Patients Opt for Surgery

Recognitions and Honors:

Chairman of the Board, the North Carolina Healthcare Quality Alliance December 2016 – present; Member, North Carolina Institute of Medicine Task Force on Health Care Analytic (Established by NC DHHS to recommend quality measurements for North Carolina’s Medicaid transition to managed care / Medicaid Reform), January through May 2017Member, the Quality Strategy Subcommittee of the Medical Care Advisory Committee for NC DHHS, 5/18 – present.

AOA Visiting Professorship, UNC School of Medicine, Gamma Chapter, March 2006. Medical Care in Mississippi Post Katrina. Joseph P. Stevens Teaching Award 1993, 1994, 1996, 2002, 2003, and 2006 Internal Medicine Teaching Program, Moses Cone Health System.


  • Phone Number

    919-966-2461 (Office Phone)

  • Address

    102 Mason Farm Road

    Suite 3100

    Chapel Hill, NC 27514