Simon Gray, MD, PhD

PGY-2 Resident, Internal Medicine Residency Program
PGY-2 Trainee, Physician Scientist Training Program


Undergraduate: University of Maryland
MPhil – Advanced Chemical Engineering: University of Cambridge
MD/PhD: Yale University

Career Interests

Gastroenterology – PSTP

Simon Gray was born in South Africa and grew up in Maryland. He studied Chemical Engineering as an undergraduate at the University of Maryland, Baltimore County and as a Gates-Cambridge Scholar at the University of Cambridge, where his research focused on cell separation technologies. Simon earned his MD/PhD at the Yale School of Medicine in the Department of Immunobiology. His PhD thesis was completed under the mentorship of Dr. Susan Kaech and focused on the epigenetic regulation of CD8+ T cell development. Simon plans to pursue research focused on the intersection of the gut microbiome and mucosal immunology in the gastrointestinal tract and liver. He will enter the UNC Gastroenterology fellowship in 2020 and hopes to blend his engineering and bioinformatics backgrounds with expertise in basic wet-bench research.


Gray SM*,†, Amezquita RA†, Guan T, Kleinstein SH, Kaech SM*. Polycomb repressive complex 2-mediated chromatin repression guides effector CD8+ T cell terminal differentiation and loss of multipotency. Immunity 2017; 46:596-608.

*Co-corresponding authors; †Co-first authors

Simon Gray