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DTSTART;TZID=America/New_York:20161201T120000
DTEND;TZID=America/New_York:20161201T130000
DTSTAMP:20260412T183930
CREATED:20161201T170000Z
LAST-MODIFIED:20190307T201838Z
UID:10000828-1480593600-1480597200@www.med.unc.edu
SUMMARY:Medicine Grand Rounds\, Claire M. Doerschuk "Pneumonia: Homeland Security in the Lungs!"
DESCRIPTION:Dr. Doerschuk’s Grand Rounds will focus on host defense in the lungs\, particularly how the lungs defend themselves against common stimuli such as bacterial pathogens and tobacco smoke. Airway epithelial cells\, lung macrophages and neutrophils contribute to host defense. These cells and the processes they regulate synergize to result in an integrated response. This response can go awry in many ways\, which often inform us about important mechanisms. Therapeutic interventions hold potential at many steps in this response.   \nDr. Doerschuk’s research addresses host defense mechanisms in the lungs\, particularly the inflammatory and innate immune processes that are important in the pathogenesis and course of bacterial pneumonia\, acute lung injury/acute respiratory distress syndrome\, and cigarette-smoke induced lung disease. Basic and translational studies address the mechanisms of host defense during pneumonia that focus on leukocyte recruitment\, edema\, and lung injury. These studies investigate pathogens that cause community-acquired and nosocomial pneumonias occurring in immunocompromised patients with cancer. Although these processes are important in all inflammatory lung diseases\, her work particularly addresses pneumonia and the acute respiratory distress syndrome using in vivo\, translational\, cell biological\, immunological\, and molecular approaches. Her ultimate goal is to use this knowledge to develop therapies that enhance the inflammatory response when it is beneficial to the host and dampen this response when it is harmful.
URL:https://www.med.unc.edu/medicine/event/dec-1/
CATEGORIES:Medicine Grand Rounds
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2019/02/claire-m-doerschuk.jpeg
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20161206T110000
DTEND;TZID=America/New_York:20161206T120000
DTSTAMP:20260412T183930
CREATED:20161206T160000Z
LAST-MODIFIED:20190307T201836Z
UID:10000829-1481022000-1481025600@www.med.unc.edu
SUMMARY:McAllister Heart Institute Seminar Series: Domenick Prosdocimo\, Ph.D
DESCRIPTION:Speaker: Domenick Prosdocimo\, Ph.D\, Instructor of Medicine\,Case Western Reserve University \nTopic: “Kruppel-like factor 15 regulates cardiac lipid metabolism”
URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-domenick-prosdocimo-ph-d/
CATEGORIES:Medicine Grand Rounds
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20161208T120000
DTEND;TZID=America/New_York:20161208T130000
DTSTAMP:20260412T183930
CREATED:20161208T170000Z
LAST-MODIFIED:20190307T201834Z
UID:10000830-1481198400-1481202000@www.med.unc.edu
SUMMARY:Medicine Grand Rounds\, Marco Patti "Gastroesophageal Reflux Disease: From Heartburn to Lung Fibrosis and Beyond"
DESCRIPTION:This lecture will focus on the relationship between GERD and respiratory disorders–in particular\, the possible cause and effect relationship between GERD and Idiopathic Pulmonary Fibrosis. Dr. Patti will review the possible role of GERD in rejection after lung transplantation. Strategies for addressing these problems will be presented. \nMarco G. Patti\, MD\, is an internationally known surgeon with extensive expertise in the surgical treatment of esophageal diseases. He is one of the few surgeons in the United States who focus entirely on the surgical treatment of esophageal disease\, specializing in treatment of swallowing disorders\, acid reflux and esophageal cancer. \nPatti is an authority on the use of minimally invasive surgical techniques to treat esophageal conditions. Performed through very small incisions with the use of specialized instruments and miniature cameras\, this approach can lead to a quicker and more comfortable recovery\, a shorter hospital stay and minimal scarring. “Because some of these disorders are so common\, many people tend to live with the discomfort rather than seek treatment\,” said Patti. “So when they finally come to us\, they already have fairly advanced disease.” \nGastroesophageal reflux disease\, known as GERD\, affects an estimated two to three percent of adults. In patients with GERD\, a muscle that separates the esophagus from the stomach does not close properly. This allows stomach contents to leak back\, or reflux\, into the esophagus and irritate it. Although GERD can usually be treated with lifestyle and diet changes combined with medication\, chronic reflux can cause serious complications. Repeated exposure to stomach acid can damage the esophagus and cause bleeding or ulcers. Scar tissue can narrow the esophagus and impair swallowing. Some patients with chronic GERD develop Barrett’s esophagus\, in which some of the lining of the esophagus is replaced by tissue similar to that in the intestine. This condition\, which affects about 700\,000 adults in the United States\, can progress to esophageal cancer\, which is often fatal. \n“Physicians are slowly becoming more aggressive about treating these disorder before the complications begin\,” Patti said. “I have seen too many patients who slowly develop serious damage while struggling with ineffective medications\, when a simple operation could have solved the problem.”
URL:https://www.med.unc.edu/medicine/event/dec-8/
CATEGORIES:Medicine Grand Rounds
ATTACH;FMTTYPE=image/png:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2019/02/marco-patti-md.png
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20161212T120000
DTEND;TZID=America/New_York:20161212T130000
DTSTAMP:20260412T183930
CREATED:20161212T170000Z
LAST-MODIFIED:20190307T201832Z
UID:10000832-1481544000-1481547600@www.med.unc.edu
SUMMARY:Grand Rounds: Sarah Ciccotto\, MD
DESCRIPTION:Speaker: Sarah Ciccotto\, MD\, UNC Cardiology FellowTopic: “Cardiovascular Disease in Women: Unique Risk Factors and Implications for Primary Prevention.”
URL:https://www.med.unc.edu/medicine/event/grand-rounds-sarah-ciccotto-md/
CATEGORIES:Medicine Grand Rounds
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20161215T120000
DTEND;TZID=America/New_York:20161215T130000
DTSTAMP:20260412T183930
CREATED:20161215T170000Z
LAST-MODIFIED:20240313T114506Z
UID:10000836-1481803200-1481806800@www.med.unc.edu
SUMMARY:Medicine Grand Rounds\, Eric Klett\, Louise Newton and Keelee MacPhee "A Multidisciplinary Approach to the Care of Transgender Patients"
DESCRIPTION:Dr. Eric Klett\, Dr. Keelee MacPhee\, J. Louise Newton will provide an overview of the diagnosis and care of patients with Gender Dysphoria. Diagnostic criteria for Gender Dysphoria as well as adherence to the standards of care will be discussed for medical providers who may come into contact with the transgender population in their practice. \nDr. Klett practices General Endocrinology at UNC with clinical interests in thyroid disease\, lipid disorders and transgender medicine. \nMs. Newton is the Clinical Director of Psychotherapy at Carolina Partners in Mental HealthCare. She has been a clinical educator and advocate of access to treatment for LGBTQI communities since 2001 and specializes in working with transgender and gender variant folks; many of whom are seeking assistance in removing barriers to medical care. Ms. Newton has also worked during this time educating providers about best practices in working with transgender and gender nonconforming patients. \nDr. MacPhee has been performing gender reassignment procedures since 2005. Working with the transgender and non-binary patient population\, she has seen first-hand the positive and profound effects that surgical reconstruction can have on a person’s life. Dr. MacPhee practices at Renaissance Plastic & Reconstructive Surgery in Raleigh.
URL:https://www.med.unc.edu/medicine/event/dec-15/
CATEGORIES:Medicine Grand Rounds
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/eric-klett-e1632359218193.jpeg
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20161222T120000
DTEND;TZID=America/New_York:20161222T130000
DTSTAMP:20260412T183930
CREATED:20161213T234500Z
LAST-MODIFIED:20190307T201827Z
UID:10000834-1482408000-1482411600@www.med.unc.edu
SUMMARY:Medicine Grand Rounds\, Will Pendergraft "These Are Your Kidneys on Lupus"
DESCRIPTION:Dr. Will Pendergraft is Assistant Professor of Medicine in the Division of Nephrology. His specialty areas include Glomerular disease\, vasculitis (with primary focus on ANCA vasculitis)\, lupus nephritis\, and drug-induced autoimmune disease. \nIn this lecture\, Dr. Pendergraft will describe the impact of lupus on the kidneys and review the current clinical and translational states of lupus nephritis\, including the first successful clinical trial in lupus nephritis. Lupus nephritis is the term used when lupus causes inflammation in the kidneys\, making them unable to properly remove waste from blood or control the amount of fluids in the body. Abnormal levels of waste can build up in the blood and edema can develop. Left untreated\, nephritis can lead to scarring and permanent damage to the kidneys and possibly end-stage renal disease\, requiring dialysis or a kidney transplant. It is estimated that as many as 40 percent of all people with lupus\, and as many as two-thirds of all children with lupus\, will develop kidney complications that require medical evaluation and treatment. \nDr. Pendergraft provides medical care for patients with kidney disease\, educates trainees about nephrology\, and conducts translational and clinical research with a special emphasis on autoimmune diseases that affect the kidneys. His other research interests include: \n\nUnderstanding response to therapy and relapse in lupus nephritis and ANCA vasculitis using high-resolution systems-level tools (epigenetic\, transcriptomic\, metabolomic\, proteomic and microbiomic)\nRepurposing FDA-approved drugs for use in lupus nephritis and ANCA vasculitis\nTranslational studies aimed at understanding drug-induced forms of ANCA vasculitis\nClinical trials of existing and novel biologic therapies for lupus nephritis and ANCA vasculitis\nClinical data analysis of large and unique cohorts of patients with either lupus nephritis\, ANCA vasculitis or idiopathic membranous nephropathy\nIn-depth characterization of rituximab use and development of guidelines to prevent and manage adverse event
URL:https://www.med.unc.edu/medicine/event/dec-22/
CATEGORIES:Medicine Grand Rounds
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2019/02/will-pendergraft.jpeg
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