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X-WR-CALDESC:Events for Department of Medicine
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DTSTART;TZID=America/New_York:20180201T120000
DTEND;TZID=America/New_York:20180201T130000
DTSTAMP:20260422T014030
CREATED:20180201T170000Z
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UID:10000959-1517486400-1517490000@www.med.unc.edu
SUMMARY:Medicine Grand Rounds\, Eric Juengst and Greg Copenhaver\, "The Biology and Ethics of CRISPR"
DESCRIPTION:CRISPR technology is a simple yet powerful tool for editing genomes. It allows researchers to easily alter DNA sequences and modify gene function. Its many potential applications include correcting genetic defects\, treating and preventing the spread of diseases and improving crops. However\, its promise also raises ethical concerns. Drs. Juengst and Copenhaver will explore the biological basis of CRISPR technology and its potential biomedical applications. \nEric Juengst is Professor in the Department of Social Medicine and the Department of Genetics. He also serves as Director of the UNC Center for Bioethics. Dr. Juengst’s research interests and publications have focused on the conceptual and ethical issues raised by new advances in human genetics and biotechnology. Since 1997 he has been the principal investigator of a series of N.I.H. funded research projects examining the ethical and social policy issues that will be raised by the availability of genetic and genomic technologies. His current R01 project examines ethical and social implications of “Personalized Genomic Medicine”as a paradigm for health care. \nGreg Copenhaver is a professor in the UNC Biology Department. He serves as the Director of Graduate Studies (Biology – MCDB) at UNC and as Editor-in-Chief for the peer-reviewed scientific journal PLoS Genetics. In addition\, he co-founded the biotechnology company Chromatin Inc. He has also authored or co-authored numerous research papers including publications in Science\, Nature\, PLoS Genetics\, eLife\, Proceedings of the National Academy of Sciences\, and Nature Genetics.
URL:https://www.med.unc.edu/medicine/event/feb-1/
CATEGORIES:Medicine Grand Rounds
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/eric-juengst.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180206T140000
DTEND;TZID=America/New_York:20180206T150000
DTSTAMP:20260422T014030
CREATED:20180206T190000Z
LAST-MODIFIED:20190307T185333Z
UID:10000960-1517925600-1517929200@www.med.unc.edu
SUMMARY:McAllister Heart Institute Seminar Series: Brian Jensen\, MD\, Novel roles for the nuclear receptor ROR-alpha in regulating cardiac hypertrophy
DESCRIPTION:Speaker: Brian Jensen\, MD\, Associate Professor of Medicine & Pharmacology\, UNCTopic: Novel roles for the nuclear receptor ROR-alpha in regulating cardiac hypertrophy
URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-brian-jensen-md-novel-roles-for-the-nuclear-receptor-ror-alpha-in-regulating-cardiac-hypertrophy/
CATEGORIES:Medicine Grand Rounds
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180208T120000
DTEND;TZID=America/New_York:20180208T130000
DTSTAMP:20260422T014030
CREATED:20180208T170000Z
LAST-MODIFIED:20190307T185331Z
UID:10000961-1518091200-1518094800@www.med.unc.edu
SUMMARY:Medicine Grand Rounds\, Matthew Cavender "Coronary Artery Disease in Patients with Diabetes Mellitus"
DESCRIPTION:Diabetes mellitus is a common medical problem and a significant risk factor for the development of atherosclerotic coronary artery disease. Coronary artery disease is highly prevalent and is the major cause of morbidity and mortality in diabetic patients. Dr. Cavender will discuss the link between diabetes and heart disease\, strategies to reduce cardiovascular risk in this population\, and insights from observational data on the effectiveness of therapies. \nDr. Cavender is an active interventional cardiologist with a focus on catheter-based interventions for coronary artery disease\, aortic and mitral valve disease\, peripheral vascular disease\, and cardiogenic shock. In addition to his clinical interests\, he has an active research program with an emphasis on improving the quality of health care delivery and understanding the clinical effectiveness of pharmacological and device based therapies for patients with coronary artery disease\, diabetes\, peripheral arterial disease\, and valvular heart disease. \nIn 2017\, he was selected by Cardiology Today as one of its Next Gen Innovators\, “a bright group of early career cardiologists identified as innovators in the field.”  Dr. Cavender joined UNC’s interventional cardiology team in 2016\,  and since then has been a valued faculty member\, performing procedures\, seeing patients in clinic\, and pursuing a research program.
URL:https://www.med.unc.edu/medicine/event/feb-8/
CATEGORIES:Medicine Grand Rounds
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/matthew-cavender.jpeg
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180212T120000
DTEND;TZID=America/New_York:20180212T130000
DTSTAMP:20260422T014030
CREATED:20180212T170000Z
LAST-MODIFIED:20190307T185328Z
UID:10000962-1518436800-1518440400@www.med.unc.edu
SUMMARY:Cardiovascular Grand Rounds: Dr. Gregory Means\, Drug Eluting Balloon Technology: History\, Pharmacokinetics\, Current & Future Use
DESCRIPTION:Speaker: Gregory Means\, MD\, UNC Cardiology FellowTopic: Drug Eluting Balloon Technology: History\, Pharmacokinetics\, Current & Future Use
URL:https://www.med.unc.edu/medicine/event/cardiovascular-grand-rounds-dr-gregory-means/
CATEGORIES:Medicine Grand Rounds
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180213T140000
DTEND;TZID=America/New_York:20180213T150000
DTSTAMP:20260422T014030
CREATED:20180213T190000Z
LAST-MODIFIED:20190307T185326Z
UID:10000963-1518530400-1518534000@www.med.unc.edu
SUMMARY:McAllister Heart Institute Seminar Series: Christopher L. Holley\, MD\, PhD. Non-coding RNA\, RNA modifications\, and Oxidative Stress in the Heart
DESCRIPTION:Speaker: Christopher L. Holley\, MD\, PhD\, Assistant Professor of Medicine\, Department of Cardiology\, Duke UniversityTopic: Non-coding RNA\, RNA modifications\, and Oxidative Stress in the Heart
URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-christopher-l-holley-md-phd-non-coding-rna-rna-modifications-and-oxidative-stress-in-the-heart/
CATEGORIES:Medicine Grand Rounds
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180215T120000
DTEND;TZID=America/New_York:20180215T130000
DTSTAMP:20260422T014030
CREATED:20180215T170000Z
LAST-MODIFIED:20240208T125859Z
UID:10000964-1518696000-1518699600@www.med.unc.edu
SUMMARY:Lydia Chang and Arun Kannappan\, "Sepsis Management: Beyond the Bundle"
DESCRIPTION:Sepsis remains a life-threatening disease in the setting of infection that causes significant morbidity and mortality. The new Sepsis Definitions and updated Surviving Sepsis Guidelines released in the past two years herald a time of change in the assessment and treatment of sepsis. This lecture aims to address many questions that remain unanswered in treating this illness by reviewing the latest information on epidemiology in the age of sepsis bundle implementation\, methods to predict fluid responsiveness in patients with sepsis and hypotension\, as well as new diagnostics and therapies recently approved and on the horizon. \nLydia Chang is Assistant Professor of Medicine in the division of Pulmonary Diseases and Critical Care Medicine. She specializes in critical care medicine\, respiratory failure\, ARDS\, sepsis\, medical emergency teams\, asthma\, and COPD. \n \nArun Kannappan is Chief Fellow\, Pulmonology and Critical Care. His interests include ICU outcomes\, quality improvement\, and academic education.
URL:https://www.med.unc.edu/medicine/event/feb-15/
CATEGORIES:Medicine Grand Rounds
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/lydia-chang.jpeg
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180217T080000
DTEND;TZID=America/New_York:20180217T160000
DTSTAMP:20260422T014030
CREATED:20180217T130000Z
LAST-MODIFIED:20190307T185322Z
UID:10000965-1518854400-1518883200@www.med.unc.edu
SUMMARY:4th Annual Women's Heart Symposium
DESCRIPTION:Register by February 5! Call Barbara at 919-843-5205 or email breid@med.unc.edu with first & last name\, contact number\, & t-shirt size (S\, M\, L\, XL). Lunch will be provided. \nTOPICS AT THE SYMPOSIUM INCLUDE• An overview of heart disease in women• Heart failure in women• Device therapy in women: cardiac electrophysiology\, pacemakers\, defibrillators\, and more• Cardiovascular disease and exercise• Cardiovascular disease and nutrition• Cardiovascular disease and stress• Stretching for Health \nHosted by Paula Miller\, MD\, Clinical Associate Professor\, Medical Director of Cardiac Rehabilitation\, and Director of the Women’s Heart Program at UNC School of Medicine. She will be hosting the event and giving an overview of heart disease in women.
URL:https://www.med.unc.edu/medicine/event/4th-annual-womens-heart-symposium/
CATEGORIES:Medicine Grand Rounds
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180220T140000
DTEND;TZID=America/New_York:20180220T150000
DTSTAMP:20260422T014030
CREATED:20180220T190000Z
LAST-MODIFIED:20190307T185320Z
UID:10000966-1519135200-1519138800@www.med.unc.edu
SUMMARY:McAllister Heart Institute Seminar Series: Deepak Voora\, MD\, “Genotype-informed Statin Therapy”
DESCRIPTION:Speaker: Dr. Deepak Voora\, MD\, Associate Professor of Medicine\, Department of Cardiology\, Center for Applied Genomics and Precision Medicine at Duke University Topic: “Genotype-informed Statin Therapy” \nSeminar Synopsis: Statins are among the most commonly prescribed medications to lower cholesterol and to prevent cardiovascular disease. Although well tolerated by most patients\, a significant proportion of patients develop musculoskeletal symptoms associated with statin therapy that can lead to premature statin discontinuation\, elevated cholesterol\, and increased risk for cardiovascular events. Our group was among the first to discover a reduced function genetic variant in the SLCO1B1 gene that predisposes to higher statin concentrations and statin-associated musculoskeletal symptoms (SAMS). We have extended this finding to higher cholesterol levels in patients with cardiovascular disease treated with statins and tested for effects on cardiovascular events. The statin-specific nature of SLCO1B1 associations with SAMS that we and others have identified laid the foundation to translate our findings into the clinic. We have developed a genotype-informed statin therapy (GIST) intervention based on communicating SLCO1B1 genotype based risk for SAMS and tailored prescriptions to reduce the risk of SAMS. In two prospective studies\, including a randomized clinical trial\, GIST improves perceptions of statin therapy\, increased statin re-initiation\, and lowered cholesterol levels in patients with statin-intolerance.
URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-dr-deepak-voora-md-201cgenotype-informed-statin-therapy201d/
CATEGORIES:Medicine Grand Rounds
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180222T120000
DTEND;TZID=America/New_York:20180222T130000
DTSTAMP:20260422T014030
CREATED:20180222T170000Z
LAST-MODIFIED:20190307T185318Z
UID:10000967-1519300800-1519304400@www.med.unc.edu
SUMMARY:Medicine Grand Rounds\, Nancy Allbritton "Organs-on-Chips"
DESCRIPTION:Organ-on-chips are miniaturized devices that arrange living cells to simulate functional subunits of tissues and organs. These microdevices provide exquisite control of tissue microenviroment for the investigation of organ-level physiology and disease. Human organ-on-chips are expected to transform biomedical research providing platforms that accurately replicate human tissues\, enable a better understanding of human-to-human physiologic variations and even permit patient-specific organ mimics. These human organ facsimiles will fundamentally alter drug discovery and development by providing human constructs for screening assays\, toxicity measurements and investigation of molecular-level drug actions. \nNancy L. Allbritton is the Kenan Professor and Chair of the Joint Department of Biomedical Engineering at UNC and NC State\, and Kenan Professor in the UNC Department of Chemistry.  Her research focuses on the development of novel technologies for applications in single-cell analysis\, micro-arrays and fluidics\, and organ-on-chip. It has resulted in over 180 full-length journal publications and patents and led to 15 commercial products. Her research program has been well funded by the National Institutes of Health with nearly $60 million in grants since 1994.
URL:https://www.med.unc.edu/medicine/event/feb-22/
CATEGORIES:Medicine Grand Rounds
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/nancy-allbritton.jpeg
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180226T120000
DTEND;TZID=America/New_York:20180226T130000
DTSTAMP:20260422T014030
CREATED:20180110T232000Z
LAST-MODIFIED:20190307T185315Z
UID:10000948-1519646400-1519650000@www.med.unc.edu
SUMMARY:Cardiovascular Grand Rounds: Dr. Faisal Syed\, “Sudden Death in Mitral Valve Prolapse”
DESCRIPTION:Speaker: Faisal Syed\, MBChB\, Assistant Professor of Medicine\, UNC CardiologyTopic: “Sudden Death in Mitral Valve Prolapse”
URL:https://www.med.unc.edu/medicine/event/cardiovascular-grand-rounds-dr-faisal-syed/
CATEGORIES:Medicine Grand Rounds
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180227T140000
DTEND;TZID=America/New_York:20180227T150000
DTSTAMP:20260422T014030
CREATED:20180227T190000Z
LAST-MODIFIED:20190307T184832Z
UID:10000968-1519740000-1519743600@www.med.unc.edu
SUMMARY:McAllister Heart Institute Seminar Series: Douglas A. Marchuk\, PhD\, “Cerebral Cavernous Malformations: The Path from Gene Discovery to Therapy”
DESCRIPTION:Speaker: Dr. Douglas A. Marchuk\, PhD\, James B. Duke Professor\, Dept. of Molecular Genetics and Microbiology at Duke University Topic: “Cerebral Cavernous Malformations: The Path from Gene Discovery to Therapy”
URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-dr-douglas-a-marchuk-phd-201ccerebral-cavernous-malformations-the-path-from-gene-discovery-to-therapy201d/
CATEGORIES:Medicine Grand Rounds
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