BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Department of Medicine - ECPv6.15.18//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-ORIGINAL-URL:https://www.med.unc.edu/medicine X-WR-CALDESC:Events for Department of Medicine REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20170312T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20171105T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20180311T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20181104T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20190310T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20191103T060000 END:STANDARD END:VTIMEZONE BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20170312T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20171105T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20180311T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20181104T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20190310T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20191103T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/New_York:20180130T140000 DTEND;TZID=America/New_York:20180130T150000 DTSTAMP:20260419T050436 CREATED:20180130T190000Z LAST-MODIFIED:20190307T185337Z UID:10000958-1517320800-1517324400@www.med.unc.edu SUMMARY:McAllister Heart Institute Seminar Series: Hossein Ardehali\, MD\, PhD\, "Role of Iron in Cardiovascular Disease" DESCRIPTION:Speaker: Hossein Ardehali\, MD\, PhD\, Director of the Center for Molecular Cardiology & the Medical Scientists Program at Northwestern UniversityTopic: Role of Iron in Cardiovascular Disease URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-hossein-ardehali-md-phd-role-of-iron-in-cardiovascular-disease/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180201T120000 DTEND;TZID=America/New_York:20180201T130000 DTSTAMP:20260419T050436 CREATED:20180201T170000Z LAST-MODIFIED:20190325T143306Z UID:10000959-1517486400-1517490000@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, Eric Juengst and Greg Copenhaver\, "The Biology and Ethics of CRISPR" DESCRIPTION:CRISPR technology is a simple yet powerful tool for editing genomes. It allows researchers to easily alter DNA sequences and modify gene function. Its many potential applications include correcting genetic defects\, treating and preventing the spread of diseases and improving crops. However\, its promise also raises ethical concerns. Drs. Juengst and Copenhaver will explore the biological basis of CRISPR technology and its potential biomedical applications. \nEric Juengst is Professor in the Department of Social Medicine and the Department of Genetics. He also serves as Director of the UNC Center for Bioethics. Dr. Juengst’s research interests and publications have focused on the conceptual and ethical issues raised by new advances in human genetics and biotechnology. Since 1997 he has been the principal investigator of a series of N.I.H. funded research projects examining the ethical and social policy issues that will be raised by the availability of genetic and genomic technologies. His current R01 project examines ethical and social implications of “Personalized Genomic Medicine”as a paradigm for health care. \nGreg Copenhaver is a professor in the UNC Biology Department. He serves as the Director of Graduate Studies (Biology – MCDB) at UNC and as Editor-in-Chief for the peer-reviewed scientific journal PLoS Genetics. In addition\, he co-founded the biotechnology company Chromatin Inc. He has also authored or co-authored numerous research papers including publications in Science\, Nature\, PLoS Genetics\, eLife\, Proceedings of the National Academy of Sciences\, and Nature Genetics. URL:https://www.med.unc.edu/medicine/event/feb-1/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/eric-juengst.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180206T140000 DTEND;TZID=America/New_York:20180206T150000 DTSTAMP:20260419T050436 CREATED:20180206T190000Z LAST-MODIFIED:20190307T185333Z UID:10000960-1517925600-1517929200@www.med.unc.edu SUMMARY:McAllister Heart Institute Seminar Series: Brian Jensen\, MD\, Novel roles for the nuclear receptor ROR-alpha in regulating cardiac hypertrophy DESCRIPTION:Speaker: Brian Jensen\, MD\, Associate Professor of Medicine & Pharmacology\, UNCTopic: Novel roles for the nuclear receptor ROR-alpha in regulating cardiac hypertrophy URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-brian-jensen-md-novel-roles-for-the-nuclear-receptor-ror-alpha-in-regulating-cardiac-hypertrophy/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180208T120000 DTEND;TZID=America/New_York:20180208T130000 DTSTAMP:20260419T050436 CREATED:20180208T170000Z LAST-MODIFIED:20190307T185331Z UID:10000961-1518091200-1518094800@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, Matthew Cavender "Coronary Artery Disease in Patients with Diabetes Mellitus" DESCRIPTION:Diabetes mellitus is a common medical problem and a significant risk factor for the development of atherosclerotic coronary artery disease. Coronary artery disease is highly prevalent and is the major cause of morbidity and mortality in diabetic patients. Dr. Cavender will discuss the link between diabetes and heart disease\, strategies to reduce cardiovascular risk in this population\, and insights from observational data on the effectiveness of therapies. \nDr. Cavender is an active interventional cardiologist with a focus on catheter-based interventions for coronary artery disease\, aortic and mitral valve disease\, peripheral vascular disease\, and cardiogenic shock. In addition to his clinical interests\, he has an active research program with an emphasis on improving the quality of health care delivery and understanding the clinical effectiveness of pharmacological and device based therapies for patients with coronary artery disease\, diabetes\, peripheral arterial disease\, and valvular heart disease. \nIn 2017\, he was selected by Cardiology Today as one of its Next Gen Innovators\, “a bright group of early career cardiologists identified as innovators in the field.” Dr. Cavender joined UNC’s interventional cardiology team in 2016\, and since then has been a valued faculty member\, performing procedures\, seeing patients in clinic\, and pursuing a research program. URL:https://www.med.unc.edu/medicine/event/feb-8/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/matthew-cavender.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180212T120000 DTEND;TZID=America/New_York:20180212T130000 DTSTAMP:20260419T050436 CREATED:20180212T170000Z LAST-MODIFIED:20190307T185328Z UID:10000962-1518436800-1518440400@www.med.unc.edu SUMMARY:Cardiovascular Grand Rounds: Dr. Gregory Means\, Drug Eluting Balloon Technology: History\, Pharmacokinetics\, Current & Future Use DESCRIPTION:Speaker: Gregory Means\, MD\, UNC Cardiology FellowTopic: Drug Eluting Balloon Technology: History\, Pharmacokinetics\, Current & Future Use URL:https://www.med.unc.edu/medicine/event/cardiovascular-grand-rounds-dr-gregory-means/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180213T140000 DTEND;TZID=America/New_York:20180213T150000 DTSTAMP:20260419T050436 CREATED:20180213T190000Z LAST-MODIFIED:20190307T185326Z UID:10000963-1518530400-1518534000@www.med.unc.edu SUMMARY:McAllister Heart Institute Seminar Series: Christopher L. Holley\, MD\, PhD. Non-coding RNA\, RNA modifications\, and Oxidative Stress in the Heart DESCRIPTION:Speaker: Christopher L. Holley\, MD\, PhD\, Assistant Professor of Medicine\, Department of Cardiology\, Duke UniversityTopic: Non-coding RNA\, RNA modifications\, and Oxidative Stress in the Heart URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-christopher-l-holley-md-phd-non-coding-rna-rna-modifications-and-oxidative-stress-in-the-heart/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180215T120000 DTEND;TZID=America/New_York:20180215T130000 DTSTAMP:20260419T050436 CREATED:20180215T170000Z LAST-MODIFIED:20240208T125859Z UID:10000964-1518696000-1518699600@www.med.unc.edu SUMMARY:Lydia Chang and Arun Kannappan\, "Sepsis Management: Beyond the Bundle" DESCRIPTION:Sepsis remains a life-threatening disease in the setting of infection that causes significant morbidity and mortality. The new Sepsis Definitions and updated Surviving Sepsis Guidelines released in the past two years herald a time of change in the assessment and treatment of sepsis. This lecture aims to address many questions that remain unanswered in treating this illness by reviewing the latest information on epidemiology in the age of sepsis bundle implementation\, methods to predict fluid responsiveness in patients with sepsis and hypotension\, as well as new diagnostics and therapies recently approved and on the horizon. \nLydia Chang is Assistant Professor of Medicine in the division of Pulmonary Diseases and Critical Care Medicine. She specializes in critical care medicine\, respiratory failure\, ARDS\, sepsis\, medical emergency teams\, asthma\, and COPD. \n \nArun Kannappan is Chief Fellow\, Pulmonology and Critical Care. His interests include ICU outcomes\, quality improvement\, and academic education. URL:https://www.med.unc.edu/medicine/event/feb-15/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/lydia-chang.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180217T080000 DTEND;TZID=America/New_York:20180217T160000 DTSTAMP:20260419T050436 CREATED:20180217T130000Z LAST-MODIFIED:20190307T185322Z UID:10000965-1518854400-1518883200@www.med.unc.edu SUMMARY:4th Annual Women's Heart Symposium DESCRIPTION:Register by February 5! Call Barbara at 919-843-5205 or email breid@med.unc.edu with first & last name\, contact number\, & t-shirt size (S\, M\, L\, XL). Lunch will be provided. \nTOPICS AT THE SYMPOSIUM INCLUDE• An overview of heart disease in women• Heart failure in women• Device therapy in women: cardiac electrophysiology\, pacemakers\, defibrillators\, and more• Cardiovascular disease and exercise• Cardiovascular disease and nutrition• Cardiovascular disease and stress• Stretching for Health \nHosted by Paula Miller\, MD\, Clinical Associate Professor\, Medical Director of Cardiac Rehabilitation\, and Director of the Women’s Heart Program at UNC School of Medicine. She will be hosting the event and giving an overview of heart disease in women. URL:https://www.med.unc.edu/medicine/event/4th-annual-womens-heart-symposium/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180220T140000 DTEND;TZID=America/New_York:20180220T150000 DTSTAMP:20260419T050436 CREATED:20180220T190000Z LAST-MODIFIED:20190307T185320Z UID:10000966-1519135200-1519138800@www.med.unc.edu SUMMARY:McAllister Heart Institute Seminar Series: Deepak Voora\, MD\, “Genotype-informed Statin Therapy” DESCRIPTION:Speaker: Dr. Deepak Voora\, MD\, Associate Professor of Medicine\, Department of Cardiology\, Center for Applied Genomics and Precision Medicine at Duke University Topic: “Genotype-informed Statin Therapy” \nSeminar Synopsis: Statins are among the most commonly prescribed medications to lower cholesterol and to prevent cardiovascular disease. Although well tolerated by most patients\, a significant proportion of patients develop musculoskeletal symptoms associated with statin therapy that can lead to premature statin discontinuation\, elevated cholesterol\, and increased risk for cardiovascular events. Our group was among the first to discover a reduced function genetic variant in the SLCO1B1 gene that predisposes to higher statin concentrations and statin-associated musculoskeletal symptoms (SAMS). We have extended this finding to higher cholesterol levels in patients with cardiovascular disease treated with statins and tested for effects on cardiovascular events. The statin-specific nature of SLCO1B1 associations with SAMS that we and others have identified laid the foundation to translate our findings into the clinic. We have developed a genotype-informed statin therapy (GIST) intervention based on communicating SLCO1B1 genotype based risk for SAMS and tailored prescriptions to reduce the risk of SAMS. In two prospective studies\, including a randomized clinical trial\, GIST improves perceptions of statin therapy\, increased statin re-initiation\, and lowered cholesterol levels in patients with statin-intolerance. URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-dr-deepak-voora-md-201cgenotype-informed-statin-therapy201d/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180222T120000 DTEND;TZID=America/New_York:20180222T130000 DTSTAMP:20260419T050436 CREATED:20180222T170000Z LAST-MODIFIED:20190307T185318Z UID:10000967-1519300800-1519304400@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, Nancy Allbritton "Organs-on-Chips" DESCRIPTION:Organ-on-chips are miniaturized devices that arrange living cells to simulate functional subunits of tissues and organs. These microdevices provide exquisite control of tissue microenviroment for the investigation of organ-level physiology and disease. Human organ-on-chips are expected to transform biomedical research providing platforms that accurately replicate human tissues\, enable a better understanding of human-to-human physiologic variations and even permit patient-specific organ mimics. These human organ facsimiles will fundamentally alter drug discovery and development by providing human constructs for screening assays\, toxicity measurements and investigation of molecular-level drug actions. \nNancy L. Allbritton is the Kenan Professor and Chair of the Joint Department of Biomedical Engineering at UNC and NC State\, and Kenan Professor in the UNC Department of Chemistry. Her research focuses on the development of novel technologies for applications in single-cell analysis\, micro-arrays and fluidics\, and organ-on-chip. It has resulted in over 180 full-length journal publications and patents and led to 15 commercial products. Her research program has been well funded by the National Institutes of Health with nearly $60 million in grants since 1994. URL:https://www.med.unc.edu/medicine/event/feb-22/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/nancy-allbritton.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180226T120000 DTEND;TZID=America/New_York:20180226T130000 DTSTAMP:20260419T050436 CREATED:20180110T232000Z LAST-MODIFIED:20190307T185315Z UID:10000948-1519646400-1519650000@www.med.unc.edu SUMMARY:Cardiovascular Grand Rounds: Dr. Faisal Syed\, “Sudden Death in Mitral Valve Prolapse” DESCRIPTION:Speaker: Faisal Syed\, MBChB\, Assistant Professor of Medicine\, UNC CardiologyTopic: “Sudden Death in Mitral Valve Prolapse” URL:https://www.med.unc.edu/medicine/event/cardiovascular-grand-rounds-dr-faisal-syed/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180227T140000 DTEND;TZID=America/New_York:20180227T150000 DTSTAMP:20260419T050436 CREATED:20180227T190000Z LAST-MODIFIED:20190307T184832Z UID:10000968-1519740000-1519743600@www.med.unc.edu SUMMARY:McAllister Heart Institute Seminar Series: Douglas A. Marchuk\, PhD\, “Cerebral Cavernous Malformations: The Path from Gene Discovery to Therapy” DESCRIPTION:Speaker: Dr. Douglas A. Marchuk\, PhD\, James B. Duke Professor\, Dept. of Molecular Genetics and Microbiology at Duke University Topic: “Cerebral Cavernous Malformations: The Path from Gene Discovery to Therapy” URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-dr-douglas-a-marchuk-phd-201ccerebral-cavernous-malformations-the-path-from-gene-discovery-to-therapy201d/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180301T120000 DTEND;TZID=America/New_York:20180301T130000 DTSTAMP:20260419T050436 CREATED:20180301T170000Z LAST-MODIFIED:20190307T184830Z UID:10000969-1519905600-1519909200@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, Ana Felix "A Rational Approach to the Painful Back" DESCRIPTION:Busy clinicians need a focused clinical approach to both the diagnostic and imaging challenges of diagnosis in patients presenting with back pain and neurological symptoms. \nAna Felix is an Assistant Professor of Medicine in the Division of General Medicine and Clinical Epidemiology. She is an expert neurologist\, seeing patients who have MS and a variety of other neurological conditions. Dr. Felix is particularly interested in stroke\, TIA in adults and children\, vascular neurology\, vascular ultrasound\, stroke in the young and in women\, and hypercoagulable disorders associated with stroke. URL:https://www.med.unc.edu/medicine/event/mar-1/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/ana-felix.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180306T140000 DTEND;TZID=America/New_York:20180306T150000 DTSTAMP:20260419T050436 CREATED:20180306T190000Z LAST-MODIFIED:20190307T184828Z UID:10000971-1520344800-1520348400@www.med.unc.edu SUMMARY:McAllister Heart Institute Seminar Series: James F. Martin\, MD\, PhD\, "Hippo Signaling in Heart Regeneration" DESCRIPTION:Speaker: James F. Martin\, MD\, PhD\, Vivian L. Smith Professor in Regenerative Medicine\, Baylor College of Medicine; Director\, Cardiomyocyte Renewal Lab\, Texas Heart InstituteTopic: “Hippo Signaling in Heart Regeneration” \nSeminar Synopsis: Dr. Martin is an internationally recognized developmental and regenerative biologist who has made fundamental contributions to our understanding of development\, disease\, and regeneration. He has authored more than 135 peer-reviewed papers in top journals such as Nature\, Science\, Cell\, Developmental Cell\, Plos Genetics\, Development\, and PNAS. His recent groundbreaking work on the Hippo pathway in heart size regulation is a landmark study that led to the insight that the Hippo pathway is an inhibitor of adult heart muscle regeneration. Dr. Martin’s insights revealed new avenues for treatment of human heart failure. Dr. Martin has made fundamental insights into the role of the transcription factor Pitx2 in atrial fibrillation\, the most common sustained arrhythmia in the human population. He made use of the mouse model to investigate Pitx2 in atrial homeostasis but also in left right asymmetric morphogenesis that is essential for human development. Dr. Martin’s studies investigating Pitx2 function in craniofacial development provided insight into the molecular basis of Rieger syndrome. He uncovered a pivotal function for Bmp signaling in endothelial-mesenchymal transition and cardiac valve development. Dr. Martin’s studies uncovered a novel role for canonical Wnt signaling in cardiac progenitor cell diversification. He found the first microRNA implicated in orofacial clefting. Dr. Martin’s studies are highly cited and also reported on by the lay media. URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-james-f-martin-md-phd-hippo-signaling-in-heart-regeneration/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180307T000000 DTEND;TZID=America/New_York:20180309T000000 DTSTAMP:20260419T050436 CREATED:20180307T050000Z LAST-MODIFIED:20190307T184825Z UID:10000974-1520380800-1520553600@www.med.unc.edu SUMMARY:42nd Annual Internal Medicine Conference DESCRIPTION: URL:https://www.med.unc.edu/medicine/event/42nd-annual-internal-medicine-conference/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180308T120000 DTEND;TZID=America/New_York:20180308T130000 DTSTAMP:20260419T050436 CREATED:20180308T170000Z LAST-MODIFIED:20190307T184823Z UID:10000976-1520510400-1520514000@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, Anne Peery "Diverticulitis -- A Medical Perspective" DESCRIPTION:Dr. Peery focuses on benign conditions of the colon\, including diverticular disease and hemorrhoids. Despite the extremely common nature of these conditions\, there is little scientifically-based evidence to guide the care of patients with these commonly-encountered conditions. Indeed\, most of the algorithms of care for these diseases are governed by opinions and best guesses as to good practice rather than hard evidence. Dr. Peery’s research has challenged long-held beliefs about risk factors for uncomplicated diverticulosis and raised new questions about a long neglected disease. She recently served as a content expert and co-authored the guideline for the management of acute diverticulitis for the American Gastroenterological Association. She also co-authored a commentary that addressed a controversial recommendation generated by the guideline. \nDr. Peery recently received a career development award by the National Institutes of Health to study the effectiveness\, benefits\, and harms of antibiotics for acute diverticulitis. In addition\, this award will allow her to develop a novel patient-reported outcome measure for acute diverticulitis. Her group is also studying the utilization of surgery for non-malignant colorectal diseases. URL:https://www.med.unc.edu/medicine/event/mar-8/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/anne-peery.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180310T070000 DTEND;TZID=America/New_York:20180310T121500 DTSTAMP:20260419T050436 CREATED:20180310T120000Z LAST-MODIFIED:20190307T184821Z UID:10000978-1520665200-1520684100@www.med.unc.edu SUMMARY:Integrated Care of Patients with Atrial Fibrillation: A Satellite Symposium DESCRIPTION:Course Description – Integrated Care of Patients with Atrial Fibrillation: A Satellite Symposium – March 10\, 2018 (7:00am – 12:15pm)Atrial Fibrillation is best managed by treating it as a “chronic disease” with episodic symptoms which can be successfully managed through a coordinated multidisciplinary model. This symposium will provide education to primary care providers and cardiologists on the importance of an integrated model of care for AF and strategies for implementing such an approach. This event will be held at the The Friday Center in Chapel Hill on March 10\, 2018. \nAgenda Highlights: \n•Patient perspective: My life with Atrial Fibrillation – Marcia Van Riper\, RN\, PhD \n•Integrated care of Atrial Fibrillation: What is it and how do we get there? Anil Gehi\, MD \n•The importance of shared decision-making in discussions about anticoagulation and stroke prophylaxis – Zack Deyo\, PharmD \n•Addressing obesity/physical inactivity – Sriram Machineni\, MD URL:https://www.med.unc.edu/medicine/event/integrated-care-of-patients-with-atrial-fibrillation-a-satellite-symposium/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180313T090000 DTEND;TZID=America/New_York:20180313T170000 DTSTAMP:20260419T050436 CREATED:20180313T130000Z LAST-MODIFIED:20190307T184819Z UID:10000980-1520931600-1520960400@www.med.unc.edu SUMMARY:2018 McAllister Heart Institute/Integrative Vascular Biology Research Symposium DESCRIPTION:UNC’s Integrative Vascular Biology (IVB) Training Program and the McAllister Heart Institute (MHI) jointly announce their Annual Research Symposium on Tuesday\, March 13\, 2018. This year’s event will be held from 9AM – 5PM at the George Watts Hill Alumni Center on the UNC campus (150 Stadium Drive\, Chapel Hill\, NC 27514). The symposium highlights research from graduate students\, postdocs\, and medical fellows within the cardiovascular community at UNC and the greater Chapel Hill area and promotes multi-disciplinary collaborative research in this important field. This year’s keynote speakers will be Caroline and Geoffrey Burns (Harvard University) who will jointly present a talk entitled “New insights into zebrafish cardiovascular development and regeneration” and Karen Hirschi (Yale University) who will present a talk entitled “Regulation of endothelial cell specification”. \nAbstract submission – For those who wish to present data at the symposium\, the abstract submission deadline is Monday\, February 26th. Abstracts should include a title and all authors and are limited to 250 words (not including the title\, etc). Note that you will need to have your abstract on hand during the registration process\, and please indicate whether you wish to be considered for a limited number of oral presentations. Poster board dimensions are 3ft high by 4ft wide. For more information please contact Hannah Perrin (hjperrin@email.unc.edu). \nThe registration deadline for those not presenting is March 8th. URL:https://www.med.unc.edu/medicine/event/2018-mcallister-heart-institute-integrative-vascular-biology-research-symposium/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180315T120000 DTEND;TZID=America/New_York:20180315T130000 DTSTAMP:20260419T050436 CREATED:20180315T160000Z LAST-MODIFIED:20190307T184817Z UID:10000982-1521115200-1521118800@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, Brad Drummond "Chronic Obstructive Pulmonary Disease -- Where We Are in 2018" DESCRIPTION:Chronic obstructive pulmonary disease (COPD) is the umbrella term for the group of tobacco-related lung diseases including emphysema and chronic bronchitis. COPD is the third leading cause of death in the United States\, with an estimated 650\,000 North Carolinians living with COPD. Recent guidelines have proposed a multidimensional assessment to define disease control and inform appropriate inhaler selection. With more than 18 FDA-approved maintenance inhalers available for COPD\, including multiple delivery devices\, selection of appropriate inhaler and device can be complex. Dr. Drummond will review the recent updates to the COPD management guidelines\, as well as discuss emerging evidence regarding the role of peak inspiratory flow measurements to inform optimal inhaler selection for COPD patients. \nDr. Drummond is an Associate Professor of Medicine in the Division of Pulmonary Diseases and Critical Care Medicine. He is the Director of the UNC Obstructive Lung Diseases Clinical and Translational Research Center located at the Meadowmont Facility. Dr. Drummond’s research interests include characterizing the mechanisms for development of chronic lung disease in individuals at-risk or with COPD\, with a focus on high-risk populations including persons living with HIV or those in rural residences. URL:https://www.med.unc.edu/medicine/event/mar-15/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/brad-drummond-e1622158061623.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180319T120000 DTEND;TZID=America/New_York:20180319T130000 DTSTAMP:20260419T050436 CREATED:20180319T160000Z LAST-MODIFIED:20190307T184815Z UID:10000985-1521460800-1521464400@www.med.unc.edu SUMMARY:Cardiovascular Grand Rounds: Dr. Joshua Vega\, “UNC Project Health for Leon: A Joint Mission for Global Health” DESCRIPTION:Speaker: Joshua Vega\, UNC Cardiology FellowTopic: “UNC Project Health for Leon: A Joint Mission for Global Health” URL:https://www.med.unc.edu/medicine/event/cardiovascular-grand-rounds-dr-joshua-vega/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180320T140000 DTEND;TZID=America/New_York:20180320T150000 DTSTAMP:20260419T050436 CREATED:20180320T180000Z LAST-MODIFIED:20190307T184813Z UID:10000987-1521554400-1521558000@www.med.unc.edu SUMMARY:McAllister Heart Institute Seminar Series: James F. Martin\, MD\, PhD\, “Hippo Signaling in Heart Regeneration” DESCRIPTION:Speaker: Joan Taylor\, PhD\, Professor and Vice Chair for Research in Pathology and Lab Medicine\, UNC School of MedicineTopic: “GRAFs mind the GAP between muscle fate and function” \nSeminar Synopsis: The overall goal of our research is to characterize the intracellular signaling pathways that govern normal and aberrant growth responses in the cardiovascular and musculoskeletal system. For this seminar\, I will focus on the role of GRAF family member RhoGAPs in muscle fate and function. We originally identified GRAF1 (GTPase-regulator for RhoA associated with FAK) in an un-biased screen for Focal Adhesion Kinase binding partners and over the past several years we have shown that GRAF1 (Arhgap26) and it’s family members GRAF2 (Arhgap10) and -3 (Arhgap42) are critical for limiting RhoA activity in muscle (cardiac\, skeletal and smooth) wherein they play unique roles in co-regulating actin and membrane dynamics. In this seminar\, I will highlight our latest studies on GRAF3 which indicate a critical role for this protein in the development and pathogenesis of human hypertension. Moreover\, I will present new evidence to suggest that GRAF1 and GRAF2 may be equally as important for maintaining cardiac and skeletal muscle homeostasis respectively by novel mechanisms that involve mitochondrial quality control. Collectively\, our findings support the possibility that targeting GRAFs might provide promising therapeutic strategies to limit hypertension and striated muscle degeneration. URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-james-f-martin-md-phd-201chippo-signaling-in-heart-regeneration201d/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180322T000000 DTEND;TZID=America/New_York:20180322T130000 DTSTAMP:20260419T050436 CREATED:20180322T040000Z LAST-MODIFIED:20190307T184811Z UID:10000988-1521676800-1521723600@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, Edwin Kim "Drug Allergies Affecting the Care of Inpatients" DESCRIPTION:Drug allergies–in particular allergy to beta-lactam antibiotics–affects as many as 15% of all hospitalized patients. There is a growing pool of data demonstrating the significant effect a drug allergy diagnosis can have on morbidity and mortality of the hospitalized patient\, as well as the immense cost it can add to the health care system. A simple skin-based testing procedure has been commercially available since 2009; data on its use has shown that the vast majority of penicillin-allergic patients are no longer allergic at the time of testing. However\, far too few patients receive this testing. Dr. Kim will review data showing the scope of the drug allergy problem. This will include the diagnostic and therapeutic options for these patients\, with a focus on the pilot UNC allergy and immunology inpatient penicillin allergy testing program. \nEdwin Kim is specifically interested in the use of immunotherapy in the treatment of food allergy. He is the director of the UNC Allergy and Immunology Fellowship Training Program as well as of the UNC Food Allergy Initiative. URL:https://www.med.unc.edu/medicine/event/mar-22/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/edwin-kim.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180326T120000 DTEND;TZID=America/New_York:20180326T130000 DTSTAMP:20260419T050436 CREATED:20180326T160000Z LAST-MODIFIED:20190307T184809Z UID:10000989-1522065600-1522069200@www.med.unc.edu SUMMARY:Cardiovascular Grand Rounds: Jason Doherty\, PhD & Chris Morrison DESCRIPTION:Speakers: Jason Doherty\, PhD\, Clinical Assistant Professor\, Kenan-Flagler Business School and Chris Morrison from ViaVerus\, LLC\, Topic: “Tapping the Entrepreneurial Spirit” URL:https://www.med.unc.edu/medicine/event/cardiovascular-grand-rounds-jason-doherty-phd-chris-morrison/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180327T140000 DTEND;TZID=America/New_York:20180327T150000 DTSTAMP:20260419T050436 CREATED:20180327T180000Z LAST-MODIFIED:20190307T184807Z UID:10000990-1522159200-1522162800@www.med.unc.edu SUMMARY:McAllister Seminar Series: Kenneth Walsh\, PhD DESCRIPTION:Speaker: Kenneth Walsh\, PhD\, Lockhart B. McGuire Professor\, Director of Hematovascular Biology Center\, University of VirginiaTopic: “Clonal Hematopoiesis and Cardiovascular Disease: New Mechanisms\, New Therapeutic Opportunities” URL:https://www.med.unc.edu/medicine/event/mhi-seminar-series-kenneth-walsh-phd/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180329T120000 DTEND;TZID=America/New_York:20180329T130000 DTSTAMP:20260419T050436 CREATED:20180329T160000Z LAST-MODIFIED:20190307T184804Z UID:10000991-1522324800-1522328400@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, James Evans\, "Precision Medicine in the Clinic and in Public Health -- A Genomic Perspective" DESCRIPTION:Dr. Evans will discuss the realistic uses of massively parallel sequencing\, including genome scale sequencing\, in clinical medicine and public health. \nJim Evans\, MD\, PhD\, is the Bryson Distinguished Professor of Genetics and Medicine at The University of North Carolina at Chapel Hill. He directs Adult and Cancer Genetics Services and is clinically active in Medical Genetics and General Internal Medicine. He is Editor in Chief of Genetics in Medicine\, the preeminent clinically focused Medical Genetics Journal and the official journal of The American College of Genetics and Genomics. URL:https://www.med.unc.edu/medicine/event/mar-29/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/Evansweb.jpg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180403T140000 DTEND;TZID=America/New_York:20180403T150000 DTSTAMP:20260419T050436 CREATED:20180403T180000Z LAST-MODIFIED:20190307T184802Z UID:10000992-1522764000-1522767600@www.med.unc.edu SUMMARY:McAllister Heart Institute Seminar Series: Xander Wehrens\, MD\, PhD\, "Remodeling of calcium release unit proteins in Heart Failure" DESCRIPTION:Speaker: Xander Wehrens\, MD\, PhD\, Professor\, Director of Cardiovascular Research Institute\, Baylor University Topic: “Remodeling of calcium release unit proteins in Heart Failure” URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-xander-wehrens-md-phd/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180405T120000 DTEND;TZID=America/New_York:20180405T130000 DTSTAMP:20260419T050436 CREATED:20180405T160000Z LAST-MODIFIED:20190307T184800Z UID:10000993-1522929600-1522933200@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, Nigel Key "Hemophilia\, A 100-Year Story" DESCRIPTION:Although it’s been nearly a century since hemophilia was considered an early death sentence\, treating it can be time-consuming and troublesome. Many people with the blood disease give themselves frequent drug infusions to keep their condition under control\, sometimes as often as several times a week. \nSeveral newly approved medications\, while far from a cure\, aim to lift some of that burden. Some will allow patients to go longer between treatments. Another drug in development aims to overcome a problem with current treatments\, which can sometimes stop working for people whose bodies become resistant to them. \n“There’s never been a time when the pipeline is as full as it is now\,” says Nigel Key\, MB\, ChB\, a hematologist and director of the UNC Hemophilia and Thrombosis Center. “I think it’s a reflection of the ability of biotechnology to bring these things forward.” \nDr. Key is Vice Chief of the Division of Hematology/Oncology. His practice is limited to patients with non-malignant blood disorders. His particular interests are in bleeding and clotting disorders. URL:https://www.med.unc.edu/medicine/event/apr-5/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/nigel-key.jpeg END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180409T120000 DTEND;TZID=America/New_York:20180409T130000 DTSTAMP:20260419T050436 CREATED:20180409T160000Z LAST-MODIFIED:20190307T184758Z UID:10000994-1523275200-1523278800@www.med.unc.edu SUMMARY:Cardiovascular Grand Rounds : Andrew Doorey\, MD\, "A Failure to Communicate: Safety Gaps in the Cardiac Catheterization Lab" DESCRIPTION:Speaker: Andrew Doorey\, MD\, Cardiologist\, Christiana Care Health System in Wilmington\, DelawareTopic: “A Failure to Communicate: Safety Gaps in the Cardiac Catheterization Lab” URL:https://www.med.unc.edu/medicine/event/cardiovascular-grand-rounds-andrew-doorey-md-a-failure-to-communicate-safety-gaps-in-the-cardiac-catheterization-lab/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180410T140000 DTEND;TZID=America/New_York:20180410T150000 DTSTAMP:20260419T050436 CREATED:20180410T180000Z LAST-MODIFIED:20190307T184756Z UID:10000995-1523368800-1523372400@www.med.unc.edu SUMMARY:McAllister Heart Institute Seminar Series: Rong Tian\, MD\, PhD\, “Metabolic Modulation of Cardiac Remodeling” DESCRIPTION:Speaker: Rong Tian\, MD\, PhD\, Professor of Anesthesiology and Pain Medicine\, Director of the Mitochondria and Metabolism Center\, University of WashingtonTopic: “Metabolic Modulation of Cardiac Remodeling” URL:https://www.med.unc.edu/medicine/event/mcallister-heart-institute-seminar-series-rong-tian-md-phd/ LOCATION:NC CATEGORIES:Medicine Grand Rounds END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180412T120000 DTEND;TZID=America/New_York:20180412T130000 DTSTAMP:20260419T050436 CREATED:20180412T160000Z LAST-MODIFIED:20190307T184754Z UID:10000867-1523534400-1523538000@www.med.unc.edu SUMMARY:Medicine Grand Rounds\, Eric Edwards and Michael Craig\, "Best of 2017: An Update in Hospital Medicine" DESCRIPTION:Drs. Craig and Edwards will be reviewing the highlights of the latest medical literature pertaining to the practice of hospital medicine. Specific topics include updated guidelines on the treatment of C. difficile colitis\, DOACs for cancer-associated VTE\, and many more. The speakers note that the lecture will be fast-paced\, interactive\, and (hopefully) fun! \nEric Edwards is Associate Chief for Clinical Operations at Hillsborough\, and Associate Professor of Medicine and Pediatrics. \nMichael Craig is Associate Chief for Clinical Operations at Chapel Hill and Associate Professor of Medicine. URL:https://www.med.unc.edu/medicine/event/apr-12/ LOCATION:NC CATEGORIES:Medicine Grand Rounds ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/eric-edwards.jpeg END:VEVENT END:VCALENDAR