{"id":3715,"date":"2023-03-01T10:55:41","date_gmt":"2023-03-01T15:55:41","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/hematology\/?post_type=ud_entry&#038;p=3715"},"modified":"2025-12-05T10:36:12","modified_gmt":"2025-12-05T15:36:12","slug":"jonathan-serody","status":"publish","type":"ud_entry","link":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/","title":{"rendered":"Jonathan Serody, MD"},"content":{"rendered":"<div class=\"video-container\"><iframe loading=\"lazy\" width=\"560\" height=\"349\" src=\"\/\/www.youtube.com\/embed\/JY7PMsbiqf8?html5=1\" title=\"\" frameborder=\"0\" allowfullscreen><\/iframe><\/div>\n<p>Over the past decades, my laboratory and I have been interested in how to harness or enhance the immune system to treat disease. Our first studies evaluated why acute GvHD after allogeneic bone marrow transplant involved a specific number of organs regardless of the degree of MHC mismatch. We demonstrated a critical role for chemokine receptors and ligands in the trafficking of immune cells after transplantation and that GvHD occurred at sites with antigen presenting cells that were activated by pathogen associated molecular molecular patterns. Our most recent work has focused on the role of B lymphocytes in the anti-tumor immune response and characterizing antibodies generated by tumor-associated B cells. Finally, we have developed novel approaches to enhance adoptive cellular therapy (ACT) of solid tumors by activating the STING pathway during the administration of ACT.<\/p>\n","protected":false},"featured_media":4549,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"ud_division":[63,66,80,90],"class_list":["post-3715","ud_entry","type-ud_entry","status-publish","format-standard","has-post-thumbnail","hentry","ud_division-division-of-hematology","ud_division-hematology-bone-marrow-transplantation","ud_division-hematology-division-admin","ud_division-our-faculty-syndication","odd"],"acf":[],"ud_entry_custom_fields":{"ud_last_name":"Serody","ud_first_name":"Jonathan","ud_gallery_summary":"","ud_telephone":[{"ud_location":"Appointments","ud_number":"9199848341"},{"ud_location":"Fax","ud_number":"9198439103"}],"ud_email":"","ud_positions":[{"ud_title":"Chief"},{"ud_title":"Elizabeth Thomas Professor of Medicine, Microbiology and Immunology"},{"ud_title":"Director, Cellular Therapy Program, UNC Medical Center"}],"ud_options":[],"ud_sort_order":"99"},"featured_image":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif","featured_image_medium":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif","featured_image_medium_large":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif","featured_image_large":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif","yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Jonathan Serody, MD - Division of Hematology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Jonathan Serody, MD - Division of Hematology\" \/>\n<meta property=\"og:description\" content=\"Over the past decades, my laboratory and I have been interested in how to harness or enhance the immune system to treat disease. Our first studies evaluated why acute GvHD after allogeneic bone marrow transplant involved a specific number of organs regardless of the degree of MHC mismatch. We demonstrated a critical role for chemokine &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/\" \/>\n<meta property=\"og:site_name\" content=\"Division of Hematology\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-05T15:36:12+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/\",\"url\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/\",\"name\":\"Jonathan Serody, MD - Division of Hematology\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif\",\"datePublished\":\"2023-03-01T15:55:41+00:00\",\"dateModified\":\"2025-12-05T15:36:12+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif\",\"width\":1706,\"height\":2560},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Directory Entries\",\"item\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Jonathan Serody, MD\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/\",\"name\":\"Division of Hematology\",\"description\":\"Department of Medicine\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/medicine\/hematology\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Jonathan Serody, MD - Division of Hematology","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/","og_locale":"en_US","og_type":"article","og_title":"Jonathan Serody, MD - Division of Hematology","og_description":"Over the past decades, my laboratory and I have been interested in how to harness or enhance the immune system to treat disease. Our first studies evaluated why acute GvHD after allogeneic bone marrow transplant involved a specific number of organs regardless of the degree of MHC mismatch. We demonstrated a critical role for chemokine &hellip; Read more","og_url":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/","og_site_name":"Division of Hematology","article_modified_time":"2025-12-05T15:36:12+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/","url":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/","name":"Jonathan Serody, MD - Division of Hematology","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/medicine\/hematology\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#primaryimage"},"image":{"@id":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif","datePublished":"2023-03-01T15:55:41+00:00","dateModified":"2025-12-05T15:36:12+00:00","breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#primaryimage","url":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif","contentUrl":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-content\/uploads\/sites\/1285\/2023\/03\/serody-jon-scaled-1.avif","width":1706,"height":2560},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/jonathan-serody\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/medicine\/hematology\/"},{"@type":"ListItem","position":2,"name":"Directory Entries","item":"https:\/\/www.med.unc.edu\/medicine\/hematology\/people\/"},{"@type":"ListItem","position":3,"name":"Jonathan Serody, MD"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/medicine\/hematology\/#website","url":"https:\/\/www.med.unc.edu\/medicine\/hematology\/","name":"Division of Hematology","description":"Department of Medicine","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/medicine\/hematology\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-json\/wp\/v2\/ud_entry\/3715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-json\/wp\/v2\/ud_entry"}],"about":[{"href":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-json\/wp\/v2\/types\/ud_entry"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-json\/wp\/v2\/media\/4549"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-json\/wp\/v2\/media?parent=3715"}],"wp:term":[{"taxonomy":"ud_division","embeddable":true,"href":"https:\/\/www.med.unc.edu\/medicine\/hematology\/wp-json\/wp\/v2\/ud_division?post=3715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}