To investigate new methods of activating resting HIV infected cells in the laboratory.<\/td>\n<\/tr>\n
\n
Who is eligible to participate<\/strong><\/td>\n
HIV + individuals > 18 years of age; VL < 50; CD4 >300; on ART > 6 months<\/td>\n<\/tr>\n
\n
Procedure<\/strong><\/td>\n
Leukapheresis<\/td>\n<\/tr>\n
\n
Duration<\/strong><\/td>\n
2 visits (screening and leukapheresis). Duration is up to 3 years<\/td>\n<\/tr>\n
\n
Compensation<\/strong><\/td>\n
Screening visit – $25, Leukapheresis – $150. Travel & parking compensation are offered as well.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
<\/p>\n
Single Blood Draw Study<\/h3>\n
\n\n
\n
Goal<\/strong><\/td>\n
Obtain blood samples to evaluate normal immune and virologic functions responses as well as to study novel assays in virally suppressed HIV-1 positive person.<\/td>\n<\/tr>\n
\n
Who is eligible to participate<\/strong><\/td>\n
HIV+ ; 18-65 years of age; VL< 50; and on ART for 24 months<\/td>\n<\/tr>\n
\n
Procedure<\/strong><\/td>\n
Blood draws (up to 200 mL)<\/td>\n<\/tr>\n
\n
Duration<\/strong><\/td>\n
2 visits (screening and blood draw visit).<\/td>\n<\/tr>\n
\n
Compensation<\/strong><\/td>\n
Screening visit – $25, Blood draw visit – $50 if you donate < 100 mL, $100 if you donate > 100 mL. Travel & parking compensation are offered as well.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
<\/p>\n
Serial Blood Draw Study<\/h3>\n
\n\n
\n
Goal<\/strong><\/td>\n
Obtain serial blood samples from suppressed HIV infected participants to determine baseline variability in immune responses and inform what constitutes a significant change in T cell or immune responses following interventions.<\/td>\n<\/tr>\n
\n
Who is eligible to participate<\/strong><\/td>\n
HIV+ > 18 years of age; On ART > 24 months<\/td>\n<\/tr>\n
\n
Procedure<\/strong><\/td>\n
Blood draws<\/td>\n<\/tr>\n
\n
Duration<\/strong><\/td>\n
Up to 3 months with visits scheduled once a week for consecutive four weeks and then once a month for two consecutive months<\/td>\n<\/tr>\n
\n
Compensation<\/strong><\/td>\n
$35 each time you donate blood. Travel & parking compensation are offered as well.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
<\/p>\n
The Aging Study<\/h3>\n
\n\n
\n
Goal<\/strong><\/td>\n
Obtain blood sample to investigate how HIV serostatus and age impacts levels of mitochondrial function in CD8 T cells and CD8 memory phenotype. Secondary objective is to investigate how HIV serostatus and age impact mitochondrial function in CD8 T cells such as the generation of energy to support antigen-driven proliferation.<\/td>\n<\/tr>\n
\n
Who is eligible to participate<\/strong><\/td>\n
HIV + & HIV \u2013 participants; >18 years of age; HIV + individuals must have VL <50 copies\/ml for > 24 months, and CD4 >300<\/td>\n<\/tr>\n
\n
Procedure<\/strong><\/td>\n
Blood draws<\/td>\n<\/tr>\n
\n
Duration<\/strong><\/td>\n
Up to 2 visits<\/td>\n<\/tr>\n
\n
Compensation<\/strong><\/td>\n
Screening visit – $50, Blood draw visit – $100. Travel & parking compensation are offered as well.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
<\/p>\n
HIV Reservoir in Women<\/h3>\n
\n\n
\n
Goal<\/strong><\/td>\n
To characterize HIV reservoir size, stability, and persistence in women as well as evaluate approaches to disrupt HIV latency in women.<\/td>\n<\/tr>\n
\n
Who is eligible to participate<\/strong><\/td>\n
HIV-1 infected women, \u226518 and \u2264 62 years of age, on stable cART with HIV-1 RNA levels < 50 copies\/mL for at least 12 months, as measured on standard HIV RNA assays. Eligible participants must have a CD4 cell count \u2265 300<\/td>\n<\/tr>\n
\n
Procedure<\/strong><\/td>\n
Leukapheresis procedure and optional sigmoidoscopy procedure<\/td>\n<\/tr>\n
\n
Duration<\/strong><\/td>\n
Up to 3 years<\/td>\n<\/tr>\n
\n
Compensation<\/strong><\/td>\n
Visits – $50, Leukapheresis – $200, Sigmoidscopy – $300. Travel & parking compensation are offered as well.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n