Led by Martina Kovarova, PhD, Miriam Braunstein, PhD, and J. Victor Garcia, PhD, UNC School of Medicine researchers showed in vivo efficacy of a long-acting injectable formulation of the anti-TB drug rifabutin. Read more.

Researchers from the HIV Prevention Trials Network (HPTN) presented updated results from the HPTN 084 long-acting cabotegravir (CAB) for pre-exposure prophylaxis (PrEP) study at the AIDS 2022 conference in Montreal. New findings show reductions in HIV incidence were sustained in the 12 months following trial unblinding (November 5, 2020, through November 5, 2021). Read more.

Researchers from the Institute for Global Health and Infectious Diseases, the Gillings School of Global Public Health, and Center for Health Equity Research reviewed qualitative data from three “Ending the HIV Epidemic” (EHE) projects, published in the July issue of Journal of Acquired Immune Deficiency Syndrome (JAIDS). In the article, Kate Muessig, PhD, associate professor … Continued

Building on the work of Dr. Ross Boyce, Victoria Shelus studies antimalarial drug use and practice at drug shops in Uganda. In the remote villages of Bugoye sub-county at the foot of Uganda’s Rwenzori Mountains a rolling landscape stretches across lush river valleys and steep hillsides. It’s the kind of terrain that might make for … Continued

Jonathan Juliano, MD, MPSH, Professor of Infectious Diseases and Associate Director of the Institute for Global Health and Infectious Diseases, with fellow IDEEL investigators Jessica Lin, MD, MSCR, and Jonathan Parr, MD, MPH, and co-PIs from the University of Florida (UF) and Centre Pasteur Cameroon, has received a $3.4 million R01 grant award to study … Continued

Tick-borne diseases (TBD) including Spotted Fever Group Rickettsiosis (SFGR), ehrlichiosis, and increasingly Lyme disease, represent a substantial public health concern throughout much of the Southeastern United States. North Carolina experiences some of the highest rates of SFGR and ehrlichiosis in the United States, often accounting for more than of 10% and 5% of cases reported to the … Continued

In 2021, women and girls in sub-Saharan Africa accounted for three of five new HIV infections, and young women aged 15–24 years were three times as likely as young men in the same age group to be infected with HIV. Despite expanded access to oral PrEP, women are disproportionately affected by HIV experiencing considerable barriers … Continued

The 2022 HPTN Annual Meeting took place June 5-8 in Washington, D.C., bringing hundreds of worldwide researchers, collaborators, community representatives, and government health officials together to share updates and accomplishments and re-engage with each other as a community. Read more.

Infectious disease research at the UNC Institute for Global Health & Infectious Diseases (IGHID) attracts unique people driven to make big change in the world. As HIV/AIDS turned 40 in 2021, the world was immersed in a different pandemic, one that brought reminders of the tremendous change science made possible in understanding, treating and preventing … Continued

Dr. Arlene Sena and her team are working to develop a syphilis vaccine, “But we need to know what’s circulating worldwide first.” Arlene Seña, MD, MPH, a professor of medicine in the Division of Infectious Diseases, is co-project director of a cooperative research grant for a Treponema pallidum vaccine development initiative and a global clinical research consortium. … Continued

Serum therapy was used extensively before the development of antibiotics and vaccines, pioneered over a century ago in the fight against diphtheria. The discovery that serum made from the blood of immunized animals, mostly horses, could neutralize toxins and inhibit the growth of some bacteria provided an intervention — even if imperfect — for several … Continued

Chris Evans, DNP, MSN, a research instructor and assistant professor of clinical education in the Division of Infectious Diseases, was one of three recipients of the 2022 Claude Paoloni Preceptor of the Year Award! The Claude Paoloni Preceptor of the Year Award recognizes preceptors for outstanding contributions to the educational development of future pharmacists. These … Continued