The Antimicrobial Stewardship Program (ASP) of University of North Carolina Hospitals is charged with optimizing the use of antimicrobial agents at the institution. ASP was developed in July 2016 as a joint program of the Department of Pharmacy and the Divisions of Adult and Pediatric Infectious Diseases. The primary goals and objectives of the program are:

  • Optimize patient outcomes by promoting the appropriate use of antimicrobials, including the choice of drug, dosing regimen, monitoring and duration.
  • Reduce the risk of healthcare-associated infections due to multidrug resistant organisms.
  • Assist the Adult and Pediatric Infectious Diseases Divisions and Department of Pharmacy in providing a coordinated approach to antimicrobial formulary and restriction management.
  • Assist clinicians in antimicrobial decisions by integrating clinical pathways and decision support systems.
  • Assist the Adult and Pediatric Infectious Diseases Divisions and Department of Pharmacy in promoting evidence-based medicine as it relates to prescribing, preparing, administering and monitoring antimicrobials.
  • Perform medication use evaluations related to antimicrobial usage to identify areas for future intervention.
  • Provide education to medical, nursing, and pharmacy staff related to antibiotic stewardship.
  • Assist in the management of antimicrobial and vaccine shortages.
  • Assure compliance with policy standards related to antibiotic stewardship.

Antimicrobial resistance is a substantial public health threat in the United States. The inappropriate use of antimicrobials by physicians is part of the reason for the current resistance problem. Implementation of stewardship programs should prevent or slow the emergence of resistance among microorganisms. This should result in reductions of patient length of stay, adverse drug reactions, morbidity, mortality and healthcare costs.

Administration/Organization
The ASP is a joint program between the Department of Pharmacy and the Divisions of Adult and Pediatric Infectious Diseases at UNC Hospital. The main personnel involved are described below:

Jonathan J. Juliano, MD, MSPH– Medical Director, Adult Infectious Diseases

Ashley Marx, PharmD– ID Pharmacist

Lindsay Daniels, PharmD– ID Pharmacist

David Weber, MD, MPH– Adult Infectious Diseases

Zachary Willis. MD– Pediatric Infectious Diseases

Tom Belhorn, MD, PhD– Pediatric Infectious Diseases

Jessica Lin, MD– Adult Infectious Diseases

Jonathan Parr, MD– Adult Infectious Diseases

Scott Savage, PharmD– Director, Department of Pharmacy

Kayla Waldron, PharmD– Clinical Manager, Department of Pharmacy