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Department of Medicine

Hypertension Research

The physicians who work in the Hypertension Clinic are co-investigators in research studies that are examining novel treatments for patients with high blood pressure. If you are interested in participating in research, ask your physician if you might qualify for one of these studies.

Recent Publications

  • Blumenthal JA, Hinderliter AL, Smith PJ, Mabe S, Watkins LL, Craighead L, Ingle K, Tyson C, Lin PH, Kraus WE, Liao L, Sherwood A Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial. Circulation. 2021 Oct 12;144(15):1212-1226.
  • Viera AJ, Yano Y, Lin FC, Simel DL, Yun J, Dave G, Von Holle A, Viera LA, Shimbo D, Hardy ST, Donahue KE, Hinderliter A, Voisin CE, Jonas DE. Does This Adult Patient Have Hypertension?: The Rational Clinical Examination Systematic Review. JAMA. 2021 Jul 27;326(4):339-347.
  • Hinderliter AL, Smith P, Sherwood A, Blumenthal J. Lifestyle Interventions Reduce the Need for Guideline-Directed Antihypertensive Medication. Am J Hypertens. 2021 Oct 27;34(10):1100-1107.
  • Azizi M, Sanghvi K, Saxena M, Gosse P, Reilly JP, Levy T, Rump LC, Persu A, Basile J, Bloch MJ, Daemen J, Lobo MD, Mahfoud F, Schmieder RE, Sharp ASP, Weber MA, Sapoval M, Fong P, Pathak A, Lantelme P, Hsi D, Bangalore S, Witkowski A, Weil J, Kably B, Barman NC, Reeve-Stoffer H, Coleman L, McClure CK, Kirtane AJ; RADIANCE-HTN investigators. Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial. Lancet. 2021 Jun 26;397(10293):2476-2486.
  • Voora R, Hinderliter AL. Modulation of Sympathetic Overactivity to Treat Resistant Hypertension. Curr Hypertens Rep. 2018 Sep 7;20(11):92.
  • Hinderliter AL, Voora R, Colindres RE. Hypertension. In: Stouffer G, Runge M, Patterson C, Rossi J, eds. Netter’s Cardiology. 3rd ed., 2018.
  • Hinderliter AL, Voora RA, Viera AJ. Implementing ABPM into Clinical Practice. Curr Hypertens Rep. 2018 Feb 5;20(1):5.
  • Davis LL. Hypertension: How low to go when treating older adults. Journal for Nurse Practitioners. 2019 15(1): 1-6.
  • Sherwood A, Hill LK, Blumenthal JA, Hinderliter AL. The Effects of Ambulatory Blood Pressure Monitoring on Sleep Quality in Men and Women With Hypertension: Dipper vs. Nondipper and Race Differences. Am J Hypertens. 2019 Jan 1;32(1):54-60.
  • Cummings DM, Adams A, Halladay J, Hinderliter A, Donahue KE, Cene CW, Li Q, Miller C, Garcia B, Tillman J, Little E, DeWalt D. Race-Specific Patterns of Treatment Intensification Among Hypertensive Patients Using Home Blood Pressure Monitoring: Analysis Using Defined Daily Doses in the Heart Healthy Lenoir Study. Ann Pharmacother. Ann Pharmacother. 2019 Apr;53(4):333-340
  • Azizi M, Schmieder RE, Mahfoud F, Weber MA, Daemen J, Davies J, Basile J, Kirtane AJ, Wang Y, Lobo MD, Saxena M, Feyz L, Rader F, Lurz P, Sayer J, Sapoval M, Levy T, Sanghvi K, Abraham J, Sharp ASP, Fisher NDL, Bloch MJ, Reeve-Stoffer H, Coleman L, Mullin C, Mauri L; RADIANCE-HTN Investigators. Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial. Lancet. 2018 Jun 9;391(10137):2335-2345.
  • Halladay JR, Lenhart KC, Robasky K, Jones W, Homan WF, Cummings DM, Cené CW, Hinderliter AL, Miller CL, Donahue KE, Garcia BA, Keyserling TC, Ammerman AS, Patterson C, DeWalt DA, Johnston LF, Willis MS, Schisler JC. Applicability of Precision Medicine Approaches to Managing Hypertension in Rural Populations. J Pers Med. 2018 Apr 30;8(2).
  • Blumenthal JA, Sherwood A, Smith PJ, Hinderliter A. The Role of Salt Reduction in the Management of Hypertension. J Am Coll Cardiol. 2018 Apr 10;71(14):1597-1598.
  • Wu JR, Cummings DM, Li Q, Hinderliter A, Bosworth HB, Tillman J, DeWalt D. The effect of a practice-based multicomponent intervention that includes health coaching on medication adherence and blood pressure control in rural primary care. J Clin Hypertens (Greenwich). 2018 Apr;20(4):757-764.
  • DeBarmore B, Lin FC, Tuttle LA, Olsson E, Hinderliter A, Klein JL, Viera AJ. Association of ambulatory blood pressure variability with coronary artery calcium. J Clin Hypertens (Greenwich). 2018 Feb;20(2):289-296.
  • Sherwood A, Hill LK, Blumenthal JA, Hinderliter AL. Circadian hemodynamics in men and women with high blood pressure: dipper vs. nondipper and racial differences. J Hypertens. 2018 Feb;36(2):250-258.
  • Cené CW, Halladay JR, Gizlice Z, Donahue KE, Cummings DM, Hinderliter A, Miller C, Johnson LF, Garcia B, Tillman J, Little EP, Rachide MR, Keyserling TC, Ammerman A, Zhou H, Wu JR, DeWalt D. A multicomponent quality improvement intervention to improve blood pressure and reduce racial disparities in rural primary care practices. J Clin Hypertens (Greenwich). 2017 Apr;19(4):351-360.
  • Sherwood A, Smith PJ, Hinderliter AL, Georgiades A, Blumenthal JA. Effects of exercise and stress management training on nighttime blood pressure dipping in patients with coronary heart disease: A randomized, controlled trial. Am Heart J. 2017 Jan;183:85-90.
  • Tyson CC, Smith PJ, Sherwood A, Mabe S, Hinderliter AL, Blumenthal JA. Influence of Kidney Function on Blood Pressure Response to Lifestyle Modifications: Secondary Analysis From the Exercise and Nutritional Interventions for Cardiovascular Health (ENCORE) Trial. J Clin Hypertens (Greenwich). 2016 Dec;18(12):1260-1267.
  • Halladay JR, Donahue KE, Cené CW, Li Q, Cummings DM, Hinderliter AL, Miller CL, Garcia BA, Little E, Rachide M, Tillman J, Ammerman AS, DeWalt D. The association of health literacy and blood pressure reduction in a cohort of patients with hypertension: the heart healthy Lenoir trial. Patient Educ Couns. 2016 Oct 20. pii: S0738-3991(16)30484-0.
  • Hill LK, Sherwood A, Blumenthal JA, Hinderliter AL. Hemodynamics and Vascular Hypertrophy in African Americans and Caucasians With High Blood Pressure. Am J Hypertens. 2016 Aug 1. pii: hpw080.
  • Cummings DM, Wu JR, Cene C, Halladay J, Donahue KE, Hinderliter A, Miller C, Garcia B, Penn D, Tillman J, DeWalt D. Perceived Social Standing, Medication Nonadherence, and Systolic Blood Pressure in the Rural South. J Rural Health. 2016 Spring;32(2):156-63.
  • Viera AJ, Lin FC, Tuttle LA, Olsson E, Girdler SS, Hinderliter AL. Examination of Several Physiological and Psychosocial Factors Potentially Associated With Masked Hypertension Among Low-Risk Adults. J Clin Hypertens (Greenwich). 2016 Aug;18(8):784-9.