{"id":2619,"date":"2015-11-24T23:09:00","date_gmt":"2015-11-25T04:09:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/people\/tilley\/"},"modified":"2023-10-13T16:28:02","modified_gmt":"2023-10-13T20:28:02","slug":"tilley","status":"publish","type":"ud_entry","link":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/people\/tilley\/","title":{"rendered":"Stephen Tilley, MD"},"content":{"rendered":"

I am interested in understanding how the immune system causes lung disease and targeting specific immune pathways for treatment. Asthma, the most common immune-mediated lung disease, has been the focus of my research for the past 25 years. The UNC Adult Asthma Program is a comprehensive program designed to improve asthma care through research and education. In addition to basic and translational research in the Marsico Lung Institute, we conduct clinical trials with new therapies and provide educational resources to patients and health care providers. The Carolina Asthma Clinic helps patients optimize control of their asthma so that they can be free of exacerbations, off oral steroids, and maintain a normal lifestyle with minimal symptoms. While the mechanisms by which the immune system drives asthma pathogenesis are well-defined and has led to the development of some very effective therapies, sarcoidosis, another immune-mediated lung disease, remains poorly understood. I am interested in developing a personalized approach to define the molecular mechanisms driving sarcoidosis. The Granuloma Project aims to utilize spatial transcriptomics to define the molecular drivers of disease in individual patients with sarcoidosis, with the goal of offering them a targeted, more effective treatment.<\/p>\n","protected":false},"featured_media":3548,"menu_order":34,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"ud_division":[96,55,95,85],"class_list":["post-2619","ud_entry","type-ud_entry","status-publish","format-standard","has-post-thumbnail","hentry","ud_division-all-faculty-profiles","ud_division-faculty","ud_division-our-faculty-syndication","ud_division-pulmonary-sarcoidosis","odd"],"acf":[],"ud_entry_custom_fields":{"ud_last_name":"Tilley","ud_first_name":"Stephen","ud_gallery_summary":"","ud_telephone":[{"ud_location":"Appointments","ud_number":"9842153220"},{"ud_location":"Academic Office","ud_number":"9198439938"},{"ud_location":"Fax","ud_number":"9842153221"}],"ud_email":"stilley@med.unc.edu","ud_positions":[{"ud_title":"Associate Professor of Medicine"},{"ud_title":"Director, UNC Adult Asthma Program"}],"ud_options":[],"ud_sort_order":""},"featured_image":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2023\/02\/Tilley_headshot.jpeg","featured_image_medium":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2023\/02\/Tilley_headshot.jpeg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2023\/02\/Tilley_headshot.jpeg","featured_image_large":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2023\/02\/Tilley_headshot.jpeg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/medicine\/pulmonary\/wp-content\/uploads\/sites\/1321\/2023\/02\/Tilley_headshot.jpeg","yoast_head":"\nStephen Tilley, MD - 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