Research News

Christopher Dittus, DO, MPH, Associate Professor of Medicine and Clinical Director of the lymphoma program, is the senior author of a newly published study in the British Journal of Haematology evaluating a novel treatment approach for aggressive adult T-cell leukemia/lymphoma (ATLL), a rare and deadly subtype of non-Hodgkin lymphoma that primarily affects ethnic minority populations … Read more

Richard Loeser, Jr., MD, Director of the Thurston Arthritis Research Clinic and a Joseph P. Archie Eminent Professor of Medicine, was awarded a $500K grant from the Department of Defense (DoD) for his study entitled,” A novel drug discovery approach for preventing post-traumatic osteoarthritis.” The DoD’s Arthritis Research Program Focused Research Award supports high-risk high-reward … Read more

Dr. Barlowe and Dr.McGill Sarah McGill, MD, MSc a gastroenterologist and endoscopist, and Trevor Barlowe, MD, a gastroenterology fellow, have found that a newly-approved treatment for C. diff. infection, called fecal microbiota spores, may be associated with a particularly harmful rebound of infection, compared to traditional therapy. Their results were published in Clinical Gastroenterology & Hepatology. For over … Read more

Joshua Zeidner, MD Joshua Zeidner, MD, associate professor of medicine and chief of leukemia research at UNC Lineberger, is the corresponding author of a newly published study on a promising treatment approach for acute myeloid leukemia (AML). The early-phase clinical trial, conducted at 12 centers nationwide, tested whether adding the oral menin inhibitor revumenib to … Read more

Drs. Simon Gray (left) and Jeffrey Jensen (right) Jeffrey Jensen, MD, PhD, a hematology/oncology fellow, and Simon Gray, MD, PhD, an assistant professor in the Division of Gastroenterology and Hepatology, received UNC School of Medicine Physician Scientist Training Program awards. Dr. Gray received an Early-Stage Faculty award, and Dr. Jensen received a Resident/Fellowship Award, providing … Read more

John Buse, MD, PhD, Verne S. Caviness Distinguished Professor of Medicine in the Division of Endocrinology & Metabolism, led a study finding 24% of individuals with difficult-to-control type 2 diabetes also present with hypercortisolism (Cushing’s syndrome). This study, entitled CATALYST and published in Diabetes Care, was the largest and most rigorous trial ever conducted to … Read more

Left to right: Amanda E. Nelson, MD, MSCR, RhMSUS; Liubov Arbeeva, MS; Yvonne Golightly, PT, MS, PhD Amanda E. Nelson, MD, MSCR, RhMSUS, professor of medicine in the Division of Rheumatology, Allergy and Immunology, and other Thurston Arthritis Research Center researchers coauthored a study entitled, “Translational genomics of osteoarthritis in 1,962,069 individuals” in Nature. Their … Read more

Saira Sheikh, MD, Linda Coley Sewell Distinguished Professor of Medicine in the UNC Division of Rheumatology, Allergy & Immunology and Director of the Clinical Trials Program at UNC’s Thurston Arthritis Research Center, along with her brother Shehzad Sheikh, MD, PhD, Professor of Medicine in the UNC Division of Gastroenterology & Hepatology, were invited to pitch … Read more

For the first time, investigators are gaining a clearer understanding of what causes drug-induced antineutrophil cytoplasmic autoantibody (ANCA) vasculitis. In a study published in The Journal of Clinical Investigation, researchers from the University of North Carolina (UNC) Department of Medicine and Kidney Center revealed that hydralazine—a drug commonly used to treat high blood pressure—alters the structure … Read more

Stephen Schworer, MD, PhD, assistant professor of medicine in the UNC Division of Rheumatology, Allergy, and Immunology, was recently awarded the American Academy of Allergy, Asthma & Immunology (AAAAI) Foundation Faculty Development Award for his project, “T2-skewed basal cells promote small airway mucus plugging in asthma.” The AAAAI Foundation is dedicated to supporting the development … Read more

People with metastatic cancer who regularly report their symptoms via a home-based electronic monitoring system experienced improved quality of life, clinical outcomes and well-being, as well as fewer emergency department visits than those who didn’t file reports. Both groups had similar overall survival rates, according to University of North Carolina Lineberger Comprehensive Cancer Center researchers … Read more

Dr. Jenny Flythe, Sherin Ismail, Dr. Michele Jonsson-Funk An article by Sherin Ismail-Atta PharmD, PhD, epidemiology graduate student at the UNC Gillings School of Global Public Health and trainee at the UNC Kidney Center, and her mentors, Michele Jonsson-Funk, PhD, Associate Professor of Epidemiology, and Jennifer Flythe, MD, MPH, Professor of Medicine and Chief of … Read more