Research News
UNC Geriatrics Represented at the 2022 AGS Annual Scientific Meeting
Two Cardiology Clinical Trials Selected for a Top Research Site Award
UNC Health Care has been selected for a 2022 Top Research Site Award by the Heart Failure Collaboratory (HFC) and the Heart Failure Society of America (HFSA) for outstanding performance on two clinical trials: PARAGLIDE-HF, and LY3461767 in Participants With Chronic Heart Failure With Reduced Ejection Fraction. The vision of the Heart Failure Society … Read more
From Observing Patients to Artwork: Medical Humanities Program seeks to Improve Clinical Observation in Internal Medicine Residents
Each morning, Internal Medicine residents take their seats for Morning Report, a case-based resident-led discussion in which Internal Medicine residents share patient case material, develop their diagnostic skills, and solve cases together. But, four or five times a year, instead of analyzing a patient, the residents are presented with classical music, poetry, or Renaissance era … Read more
Department of Medicine Faculty Featured in School of Medicine 2021 Annual Research Report
As we all desperately await a way to treat COVID-19, beyond prevention, the following publication has metrics that are incredible (following February publication, by December 2021 it had been accessed >107K times with a >1700 Altimetric).
Hemoglobin Glycation Index, Calculated From a Single Fasting Glucose Value, as a Prediction Tool for Severe Hypoglycemia and Major Adverse Cardiovascular Events in DEVOTE
Klara R. Klein, MD, PhD, fellow in the division of endocrinology and metabolism and trainee in the UNC Physician Scientist Training Program, and John Buse, MD, PhD, chief of the division of endocrinology and metabolism, are authors of a new study published in BMJ Open Diabetes Research and Care. Hemoglobin glycation index is the difference between … Read more
Ribiero Publishes “Impact of Airway Inflammation on the Efficacy of CFTR Modulators” in the Journal Cells
Carla Ribiero, PhD, professor of medicine in the division pulmonary and critical care medicine, expands the understanding of how airway inflammation improves CFTR rescue and may benefit cystic fibrosis patients, in a new review published in Cells. The cystic fibrosis transmembrane conductance regulator (CFTR) protein is responsible for regulating the proper flow of chloride and … Read more
Carey Discussed Studies of HR-Positive and HER2-Negative Advanced Breast Cancer: Overall Survival by Subtype Across Three MONALEESA Studies
Lisa A. Carey, MD, FASCO, the L. Richardson and Marilyn Jacobs Preyer Distinguished Professor for Breast Cancer Research, Division of Oncology and Deputy Director of Clinical Sciences for the Lineberger Comprehensive Cancer Center, discusses findings from a pooled analysis of the MONALEESA-2, -3, and -7 trials. Among the findings was a consistent overall survival benefit with … Read more
Peery Lead Author of Study on Burden and Cost of GI, Liver and Pancreatic Diseases
Anne Peery, MD, MSCR, associate professor in the Division of Gastroenterology and Hepatology, is the corresponding author of a new article, “Burden and Cost of Gastrointestinal, Liver and Pancreatic Diseases in the United States: Update 2021,” published October 19 in Gastroenterology. The study concluded, “Gastrointestinal diseases are responsible for millions of health care encounters and … Read more
Phase 3 Data Show Monoclonal Antibodies Provide long-term Protection Against COVID-19
A single dose of REGEN-COV, a combination monoclonal antibody therapy, reduced the risk of COVID-19 by 81.6% several months after a single dose. UNC School of Medicine’s Myron Cohen, MD, leads monoclonal antibody research efforts as part of the NIH-sponsored COVID Prevention Network. Regeneron Pharmaceuticals, Inc. announced additional positive results from a phase 3 clinial … Read more
Batsis receives NC TraCS Institute grant to explore the early detection of sarcopenia
The NC TraCS Institute has awarded John A. Batsis, MD, and the Division of Geriatric Medicine a 1-year, team science grant to study the early detection of sarcopenia.
Muss Receives Three Research Grant Awards
Hyman Muss, MD, the Mary Jones Hudson Distinguished Professor of Geriatric Oncology in the Division of Oncology, recently received three research awards. From the Breast Cancer Research Foundation (BCRF), Muss received $190,000 in funding for “p16INK4a Expression, Chemotherapy Toxicity, and Aging in Women with Breast Cancer.” There is significant variability in chemotherapy-related toxicity in women of … Read more
Serody Receives Grant to Evaluate Epigenetic Changes in Innate Immune Cells During Stem Cell Transplantation
Jonathan Serody, MD, the Elizabeth Thomas Professor of Medicine, Microbiology and Immunology, and chief of the Division of Hematology, received an NIH (NHLBI) R01 grant of $3.4M to evaluate epigenetic changes in innate lymphoid cells as a mediator of acute Graft-Versus-Host Disease (GvHD) after stem cell transplantation. The grant is in collaboration with Samantha Pattenden, … Read more