Research News

The large, multicenter randomized controlled clinical trial is evaluating the safety and efficacy of the ProTractX3™ TTS drug coated balloon for the treatment of benign esophageal strictures. News provided by GIE Medical via PRNewswire. MINNEAPOLIS – GIE Medical, a clinical stage company developing solutions for patients suffering from benign stricture(s) of the esophagus or bowel, announced … Read more

The Patient-Centered Outcomes Research Institute (PCORI) has awarded UNC Lineberger’s Ethan Basch, MD, MSc, FASCO, $3 million in research funding to support a multi-institutional initiative to implement electronic patient-reported outcomes, or ePRO, in oncology practices across the country. “People being treated for cancer often experience a range of symptoms that can cause distress and impairment, … Read more

Division of Hematology Rafal Pawlinski, PhD, and Brandi Reeves, MD, were awarded a one-year $75,000 UNC School of Medicine Phase 2 Translational Team Science Award (TTSA) for their project, “evaluating the role of hypoxia inducible factors in endothelial and hematopoietic cells in myeloproliferative neoplasms.” Division of Endocrinology & Metabolism Emily Pfaff, PhD, spoke about a … Read more

The ARIES-HM3 Randomized Clinical Trial assessed the safety and efficacy of excluding aspirin from the antithrombotic regimen in patients with advanced heart failure who have undergone implantation of a fully magnetically levitated left ventricular assist device (LVAD). “There has been no consensus in the field about use of or dose of aspirin in the LVAD … Read more

“Many individuals with hand OA have multiple medical comorbidities and polypharmacy, which are important when considering additional treatments, particularly those with modest benefit and potential adverse effects over the long term,” she said.

Division of Infectious Diseases Edward P Browne, PhD, received a: R61 grant  from the NIDA to examine the impact of cannabinoids in HIV infected humanized mice. This is a five year, $3,465,157 grant. R21 grant from the NIAID to examine post therapy changes in CD4 T cells by single cell RNA sequencing. This award is $427,625. … Read more

Donald Caraccio, MD, principal investigator and assistant professor medicine, and Maya Styner, MD, associate professor of medicine, will lead a clinical site for the RESTORE study- REducing future fractureS and improving ouTcOmes of fRagility fracturE.    Bones in patients with osteoporosis often become fragile and have an increased risk for fracture or break. Known as fragility fractures, … Read more

Drs. Gaurav Dave, associate professor of medicine, and Abhijit V. Kshirsagar, Covington Distinguished Professor of Medicine, received a grant from the NIH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to address structural racism to reduce kidney health disparities in rural North Carolina. North Carolina has the second largest rural population in the … Read more

The NIH has awarded a multi-disciplinary team led by Ross Boyce, MD, MSc, a $4.4 million, five-year (R01) grant to evaluate the effectiveness of a chemoprevention effort designed to prevent malaria outbreaks after flooding, using a combination of interventions. Boyce is a member of the Institute for Global Health and Infectious Diseases (IGHID), an Assistant … Read more

Ronald Falk, MD, Nan and Hugh Cullman Eminent Professor of Medicine at UNC, Anthony Atala, MD, Professor of Medicine at Wake Forest University and Thomas Ortel, MD, PhD, Professor of Medicine at Duke University, will lead an effort to cultivate a highly skilled cohort of people and resources to advance research in kidney, urology, and … Read more

Angela Wahl, PhD, Balfour Sartor MD, and J. Victor Garcia, PhD, and colleagues created a germ-free mouse model to evaluate the role of the microbiome in the infection, replication, and pathogenesis of HIV and Epstein-Barr virus. 

A new study shows semaglutide 2.4 mg (Wegovy), a weekly injected prescription medication for overweight adults, may prevent major adverse cardiovascular events (MACEs) such as cardiovascular death, non-fatal heart attack or non-fatal stroke. Novo Nordisk released the results of the significant clinical trial called SELECT. The trail studied the effects of Wegovy on people with … Read more