1.0Department of Medicinehttps://www.med.unc.edu/medicineDeb Hepphttps://www.med.unc.edu/medicine/news/author/debbhepp/rich600338<blockquote class="wp-embedded-content" data-secret="DKUixE1nY9"><a href="https://www.med.unc.edu/medicine/event/dec-14/">Medicine Grand Rounds, Rumey Ishizawar “Autoimmunity Induced by Cancer Immunotherapy”</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.med.unc.edu/medicine/event/dec-14/embed/#?secret=DKUixE1nY9" width="600" height="338" title="“Medicine Grand Rounds, Rumey Ishizawar “Autoimmunity Induced by Cancer Immunotherapy”” — Department of Medicine" data-secret="DKUixE1nY9" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); /* ]]> */ </script> https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/rumey-ishizawar.jpeg400562Immune-related adverse events are an unintentional side effect of immune checkpoint inhibitors used for cancer immunotherapy. Immune checkpoint inhibitors upregulate the immune system to prevent tumor evasion and promote destruction of tumor cells. These immune checkpoint inhibitors are effective as noted by the expanding number of FDA-approved drugs in this class and number of indications. … Read more