1.0Department of Medicinehttps://www.med.unc.edu/medicineDeb Hepphttps://www.med.unc.edu/medicine/news/author/debbhepp/rich600338<blockquote class="wp-embedded-content" data-secret="M9bXXyv3AG"><a href="https://www.med.unc.edu/medicine/event/may-31/">Medicine Grand Rounds, Saira Sheikh “BAFFling New Lupus Therapies – Looking to the Future After Decades of Failed Clinical Trials”</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.med.unc.edu/medicine/event/may-31/embed/#?secret=M9bXXyv3AG" width="600" height="338" title="“Medicine Grand Rounds, Saira Sheikh “BAFFling New Lupus Therapies – Looking to the Future After Decades of Failed Clinical Trials”” — Department of Medicine" data-secret="M9bXXyv3AG" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); /* ]]> */ </script> https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/saira-sheikh.png7471048Systemic lupus erythematosus (SLE) is a chronic, debilitating autoimmune disease with heterogeneous manifestations ranging from scarring skin rash or arthritis to severe, organ-threatening involvement of the kidneys, heart, lungs or central nervous system. SLE is characterized by the presence of autoantibodies against nuclear antigens, which are thought to be caused by dysregulation of the immune … Read more