1.0Department of Medicinehttps://www.med.unc.edu/medicineDeb Hepphttps://www.med.unc.edu/medicine/news/author/debbhepp/rich600338<blockquote class="wp-embedded-content" data-secret="JPYDDIdOPI"><a href="https://www.med.unc.edu/medicine/event/oct-4/">Medicine Grand Rounds, Katya Rubinow “Can Sex Steroids Help Elucidate the Utility of HDL As an Index of Cardiovascular Risk?”</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.med.unc.edu/medicine/event/oct-4/embed/#?secret=JPYDDIdOPI" width="600" height="338" title="“Medicine Grand Rounds, Katya Rubinow “Can Sex Steroids Help Elucidate the Utility of HDL As an Index of Cardiovascular Risk?”” — Department of Medicine" data-secret="JPYDDIdOPI" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); /* ]]> */ </script> https://www.med.unc.edu/medicine/wp-content/uploads/sites/945/2018/12/katya-rubinow.jpeg250310In epidemiologic studies, sex steroid deficiency predicts cardiovascular risk in both men and women, but the utility of hormone replacement therapy for reducing cardiovascular risk remains uncertain. Exogenous sex steroids regulate plasma concentrations of high-density lipoprotein cholesterol (HDL-C), but little is known about sex steroid-mediated effects on other metrics of HDL composition and function. Understanding … Read more