{"id":38254,"date":"2019-11-05T16:15:41","date_gmt":"2019-11-05T21:15:41","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=38254"},"modified":"2023-06-06T17:49:07","modified_gmt":"2023-06-06T21:49:07","slug":"kistler-receives-pilot-award-to-test-the-feasibility-of-using-pharmacogenomics-to-reduce-medication-adverse-events","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/kistler-receives-pilot-award-to-test-the-feasibility-of-using-pharmacogenomics-to-reduce-medication-adverse-events\/","title":{"rendered":"Kistler receives pilot award to test feasibility of pharmacogenomics to reduce adverse events to medication"},"content":{"rendered":"<figure id=\"attachment_38255\" class=\"thumbnail wp-caption alignright\" style=\"width: 209px\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-38255\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-199x300.jpg\" alt=\"christine-kistler\" width=\"199\" height=\"300\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-199x300.jpg 199w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-681x1024.jpg 681w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-768x1155.jpg 768w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-1021x1536.jpg 1021w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-1361x2048.jpg 1361w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-600x903.jpg 600w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-301x453.jpg 301w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-scaled.jpg 1702w\" sizes=\"auto, (max-width: 199px) 100vw, 199px\" \/><figcaption class=\"caption wp-caption-text\">Christine Kistler, MD, MASc<\/figcaption><\/figure>\n<p>The\u00a0<a href=\"https:\/\/www.med.unc.edu\/ppmh\/\">UNC Program for Precision Medicine in Health Care (PPMH)<\/a>, which aims to transform patient care through evidence-based precision medicine, and the\u00a0<a href=\"https:\/\/tracs.unc.edu\/\">North Carolina Translational and Clinical Sciences (NC TraCS) Institute<\/a>\u00a0at The University of North Carolina at Chapel Hill (UNC-CH) have awarded three pilot grants. The pilot grants have direct clinical or human translational impact and are focused on the implementation of precision medicine approaches in the UNC Health Care System and the state of North Carolina. PPMH will be providing the matching funds for these pilot grants.<\/p>\n<p><a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/christine-kistler-md\/\">Christine Kistler, MD, MASc<\/a>, Associate Professor in the UNC Department of Medicine&#8217;s Division of Geriatric Medicine and Department of Family Medicine, will lead the study, \u201cThe Feasibility of Using a Pharmacogenetic Assay in Nursing Home Residents to Reduce Adverse Events (FOGI-NH)\u201d that will focus on testing the feasibility of using pharmacogenomics to reduce medication adverse events in nursing home residents. The PGx1 assay, developed by the Wiltshire lab in the UNC School of Pharmacy\u2019s Center for Pharmacogenomics and Individualized Therapy, evaluates 30 genes to determine how a patient will respond to 100+ drugs. Dr. Kistler will evaluate the ability to conduct a larger trial to examine the effectiveness of the PGx1 assay with nursing home residents and determine how the assay can be most effectively utilized in the nursing home setting.<\/p>\n<p>Other pilot awardees include Kelli Allen, PhD, Pengda Liu, PhD, and Ian Davis, MD, PhD.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The\u00a0UNC Program for Precision Medicine in Health Care (PPMH), which aims to transform patient care through evidence-based precision medicine, and the\u00a0North Carolina Translational and Clinical Sciences (NC TraCS) Institute\u00a0at The University of North Carolina at Chapel Hill (UNC-CH) have awarded three pilot grants. The pilot grants have direct clinical or human translational impact and are &hellip; <a href=\"https:\/\/www.med.unc.edu\/medicine\/news\/kistler-receives-pilot-award-to-test-the-feasibility-of-using-pharmacogenomics-to-reduce-medication-adverse-events\/\" aria-label=\"Read more about Kistler receives pilot award to test feasibility of pharmacogenomics to reduce adverse events to medication\">Read more<\/a><\/p>\n","protected":false},"author":69419,"featured_media":38286,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[99,2],"tags":[84],"class_list":["post-38254","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-geriatric-medicine","category-news","tag-84","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Kistler receives pilot award to test feasibility of pharmacogenomics to reduce adverse events to medication | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/kistler-receives-pilot-award-to-test-the-feasibility-of-using-pharmacogenomics-to-reduce-medication-adverse-events\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kistler receives pilot award to test feasibility of pharmacogenomics to reduce adverse events to medication | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"The\u00a0UNC Program for Precision Medicine in Health Care (PPMH), which aims to transform patient care through evidence-based precision medicine, and the\u00a0North Carolina Translational and Clinical Sciences (NC TraCS) Institute\u00a0at The University of North Carolina at Chapel Hill (UNC-CH) have awarded three pilot grants. The pilot grants have direct clinical or human translational impact and are &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/kistler-receives-pilot-award-to-test-the-feasibility-of-using-pharmacogenomics-to-reduce-medication-adverse-events\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2019-11-05T21:15:41+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T21:49:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/11\/christine-kistler-1-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1920\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta 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