{"id":4362,"date":"2017-11-09T02:05:00","date_gmt":"2017-11-09T07:05:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/defining-burden-of-hepatitis-in-drc-1\/"},"modified":"2023-06-06T17:20:46","modified_gmt":"2023-06-06T21:20:46","slug":"defining-burden-of-hepatitis-in-drc-1","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/defining-burden-of-hepatitis-in-drc-1\/","title":{"rendered":"Defining the Burden of Hepatitis in the Democratic Republic of the Congo"},"content":{"rendered":"<p><!-- description --><\/p>\n<p><em>Hepatitis C virus is a curable infectious disease, but treatment remains unavailable in resource-limited settings like the Democratic Republic of the Congo (DRC). The DRC Ministry of Health asked the University of North Carolina at Chapel Hill (UNC) to help determine the burden of infection and find a way to connect people infected with the virus to treatment. Using laboratory equipment readily available in developing countries, researchers from UNC and Abbott Diagnostics were able to define and map the burden of disease in the DRC. Their findings were published in Clinical Infectious Diseases.<\/em><\/p>\n<figure class=\"thumbnail wp-caption alignright\" style=\"width: 310px\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/defining-burden-of-hepatitis-in-drc-1-image2.png\" alt=\"jonathan-parr\" width=\"300\" height=\"200\" \/><figcaption class=\"caption wp-caption-text\">Jonathan Parr, MD, MPH, stands with a technician in front of the Abbott m2000 platform used to diagnosis hepatitis C virus.<\/figcaption><\/figure>\n<p>\u201cMany people suffering from hepatitis C remain undiagnosed and untreated, despite the advent of highly effective antiviral medications,\u201d said <a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/jonathan-parr\" target=\"_blank\" rel=\"noopener\">Jonathan Parr<\/a>, MD, MPH, the study\u2019s lead author and a researcher within <a href=\"https:\/\/www.med.unc.edu\/infdis\/ideel\/\" target=\"_blank\" rel=\"noopener\">UNC\u2019s Infectious Disease Epidemiology and Ecology Lab<\/a>. \u201cWe used a simple, high throughput testing approach to map hepatitis C infections throughout the DRC. We showed that a single drop of blood collected by fingerprick can be used to identify candidates for treatment and to assess the burden of disease in resource-limited settings.\u201d<\/p>\n<p>The UNC-Abbott team adapted a common hepatitis C virus test for use with small spots of blood dried onto filter paper. The filter papers were then processed using the Abbott m2000 platform, which is widely used to detect HIV in the DRC and other countries. The researchers determined that about 1 percent or between 100,000 and 200,000 adults living in the DRC had hepatitis C.<\/p>\n<p>\u201cWe developed a simple, scalable testing algorithm that can be used in the developing world where there are minimal lab capabilities,\u201d Parr said. \u201cWe repurposed existing infrastructure, proved that the dried blood spot test worked and defined the burden of hepatitis C in the DRC.\u201d<\/p>\n<p><a href=\"http:\/\/globalhealth.unc.edu\/about\/faculty\/steven-meshnick\/\" target=\"_blank\" rel=\"noopener\">Steven Meshnick<\/a>, MD, PhD, professor of epidemiology and microbiology, and a co-author of the study said, \u201cWe\u2019ve been delighted to help our partners at the Kinshasa School of Public Health and the DRC National AIDS Control Program to strengthen viral hepatitis diagnosis in the DRC. We now hope to work with them to obtain and roll out therapies.\u201d<\/p>\n<p>This research was funded by the U.S. National Institutes of Health\u2019s National Institute of Allergy and Infectious Diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"<p><!-- description --> <\/p>\n<p class='lead'>Hepatitis C virus is a curable infectious disease, but treatment remains unavailable in resource-limited settings like the Democratic Republic of the Congo (DRC). The DRC Ministry of Health asked the University of North Carolina at Chapel Hill (UNC) to help determine the burden of infection and find a way to connect people infected with the virus to treatment. Using laboratory equipment readily available in developing countries, researchers from UNC and Abbott Diagnostics were able to define and map the burden of disease in the DRC. Their findings were published in Clinical Infectious Diseases.<\/p>\n","protected":false},"author":69419,"featured_media":4363,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[100,2],"tags":[67],"class_list":["post-4362","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-infectious-diseases","category-news","tag-67","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Defining the Burden of Hepatitis in the Democratic Republic of the Congo | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/defining-burden-of-hepatitis-in-drc-1\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Defining the Burden of Hepatitis in the Democratic Republic of the Congo | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"Hepatitis C virus is a curable infectious disease, but treatment remains unavailable in resource-limited settings like the Democratic Republic of the Congo (DRC). 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Their findings were published in Clinical Infectious Diseases.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/defining-burden-of-hepatitis-in-drc-1\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2017-11-09T07:05:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T21:20:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/defining-burden-of-hepatitis-in-drc-1-image2.png\" \/>\n\t<meta property=\"og:image:width\" content=\"298\" \/>\n\t<meta property=\"og:image:height\" content=\"217\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Kim Morris\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" 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