{"id":44382,"date":"2020-07-27T17:57:24","date_gmt":"2020-07-27T21:57:24","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=44382"},"modified":"2023-06-06T17:57:36","modified_gmt":"2023-06-06T21:57:36","slug":"air-pollution-from-wildfires-show-link-to-death-rates-in-patients-with-kidney-failure","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/air-pollution-from-wildfires-show-link-to-death-rates-in-patients-with-kidney-failure\/","title":{"rendered":"Air Pollution From Wildfires Shows Link to Death Rates in Patients With Kidney Failure"},"content":{"rendered":"<figure id=\"attachment_27245\" class=\"thumbnail wp-caption alignright\" style=\"width: 308px\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-27245\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/kshirsagar-receives-marion-stedman-covington-distinguished-professorship-image2-e1571152189158-298x300.png\" alt=\"Abhijit V. Kshirsagar, MD, MPH\" width=\"298\" height=\"300\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/kshirsagar-receives-marion-stedman-covington-distinguished-professorship-image2-e1571152189158-298x300.png 298w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/kshirsagar-receives-marion-stedman-covington-distinguished-professorship-image2-e1571152189158-150x150.png 150w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/kshirsagar-receives-marion-stedman-covington-distinguished-professorship-image2-e1571152189158-301x303.png 301w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/kshirsagar-receives-marion-stedman-covington-distinguished-professorship-image2-e1571152189158.png 486w\" sizes=\"auto, (max-width: 298px) 100vw, 298px\" \/><figcaption class=\"caption wp-caption-text\"><span class=\"discreet\">Abhijit V. Kshirsagar, MD, MPH<\/span><\/figcaption><\/figure>\n<p><a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/abhi-kshirsagar\/\"><strong>Abhijit V. Kshirsagar<\/strong><\/a>, MD, MPH, the Covington Distinguished Professor of Medicine in the division of nephrology and hypertension, is a co-author of new research published in the <strong><a href=\"https:\/\/jasn.asnjournals.org\/content\/early\/2020\/07\/15\/ASN.2019101066\">Journal of the American Society of Nephrology<\/a><\/strong> that suggests individuals with kidney failure may face a higher risk of dying prematurely if they\u2019re exposed to air pollution from wildfires.<\/p>\n<p>Wildfires generate high levels of tiny particles of air pollution\u2014called fine particulate matter\u2014that can have a range of effects on health. When inhaled, fine particulate matter can travel into the respiratory tract and bloodstream and trigger oxidative stress and inflammation. Because of their frailty, patients with kidney failure might be especially susceptible to this environmental stressor, but little is known about the effects of air pollution exposures in these individuals.<\/p>\n<p>To investigate, a team led by Ana Rappold, PhD (the US Environmental Protection Agency) and Yuzhi Xi, MSPH (UNC Gillings School of Global Public Health) analyzed information from 253 US counties near a major wildfire between 2008 and 2012.<\/p>\n<p>\u201cThis study was possible because the US Renal Disease System, a registry of patients with kidney failure included vital records on almost all US patients receiving in-center hemodialysis, as well as the zip codes of the dialysis clinics. Secondly, we utilized an air quality model to estimate daily exposure to wildfire fine particulate matter across the country at the zip codes of the dialysis units,\u201d explained\u00a0 Xi.<\/p>\n<p>Researchers found 48,454 deaths among patients with kidney failure who were receiving dialysis in the 253 counties. Each 10 \u03bcg\/m<sup>3<\/sup> increase in the concentration of wildfire fine particulate matter in the air was associated with a 4% higher death rate on the same day and a 7% higher rate over the next month. On days with wildfire fine particulate matter greater than 10 \u03bcg\/m<sup>3<\/sup>, exposure to the pollution accounted for 8.4% of daily mortality.<\/p>\n<p>\u201cThese findings support the need for more research to develop and implement interventions to manage exposure to particulate matter during wildfire smoke episodes, in this population and others with a high prevalence of frailty,&#8221; said Kshirsagar.<\/p>\n<p>Other study co-authors include Timothy J. Wade, PhD, David B. Richardson, PhD, M. Alan Brookhart, PhD, and Lauren Wyatt, PhD.<\/p>\n<p>Learn more about the study <strong><a href=\"https:\/\/jasn.asnjournals.org\/content\/early\/2020\/07\/15\/ASN.2019101066\">here<\/a><\/strong>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abhijit V. Kshirsagar, MD, MPH, the Covington Distinguished Professor of Medicine in the division of nephrology and hypertension, is a co-author of new research published in the Journal of the American Society of Nephrology that suggests individuals with kidney failure may face a higher risk of dying prematurely if they\u2019re exposed to air pollution from &hellip; <a href=\"https:\/\/www.med.unc.edu\/medicine\/news\/air-pollution-from-wildfires-show-link-to-death-rates-in-patients-with-kidney-failure\/\" aria-label=\"Read more about Air Pollution From Wildfires Shows Link to Death Rates in Patients With Kidney Failure\">Read more<\/a><\/p>\n","protected":false},"author":69419,"featured_media":27245,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[101,2],"tags":[629],"class_list":["post-44382","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nephrology","category-news","tag-629","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Air Pollution From Wildfires Shows Link to Death Rates in Patients With Kidney Failure | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/air-pollution-from-wildfires-show-link-to-death-rates-in-patients-with-kidney-failure\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Air Pollution From Wildfires Shows Link to Death Rates in Patients With Kidney Failure | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"Abhijit V. Kshirsagar, MD, MPH, the Covington Distinguished Professor of Medicine in the division of nephrology and hypertension, is a co-author of new research published in the Journal of the American Society of Nephrology that suggests individuals with kidney failure may face a higher risk of dying prematurely if they\u2019re exposed to air pollution from &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/air-pollution-from-wildfires-show-link-to-death-rates-in-patients-with-kidney-failure\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2020-07-27T21:57:24+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T21:57:36+00:00\" \/>\n<meta property=\"og:image\" 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