{"id":47044,"date":"2020-10-06T15:53:08","date_gmt":"2020-10-06T19:53:08","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=47044"},"modified":"2023-06-06T18:00:34","modified_gmt":"2023-06-06T22:00:34","slug":"new-vulnerability-found-in-lung-squamous-cancer-may-facilitate-drug-targeting-at-cellular-level","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/new-vulnerability-found-in-lung-squamous-cancer-may-facilitate-drug-targeting-at-cellular-level\/","title":{"rendered":"New Vulnerability Found in Lung Squamous Cancer May Facilitate Drug Targeting at Cellular Level"},"content":{"rendered":"<figure id=\"attachment_26777\" class=\"thumbnail wp-caption alignright\" style=\"width: 126px\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-26777\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-226x300.jpg\" alt=\"Pecot-Chad\" width=\"116\" height=\"154\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-226x300.jpg 226w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-770x1024.jpg 770w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-768x1021.jpg 768w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-1155x1536.jpg 1155w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-1540x2048.jpg 1540w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-600x798.jpg 600w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-301x400.jpg 301w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-scaled.jpg 1925w\" sizes=\"auto, (max-width: 116px) 100vw, 116px\" \/><figcaption class=\"caption wp-caption-text\"><span class=\"discreet\">Chad Pecot, MD<\/span><\/figcaption><\/figure>\n<p>New research by scientists at UNC Lineberger Comprehensive Cancer Center and colleagues shows the potential for targeting a specific circular RNA, known as CDR1as, to attack lung squamous cell cancer. The UNC work was led by <strong><a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/chad-pecot-md\/\">Chad Pecot<\/a><\/strong>, MD, associate professor of medicine in the division of oncology, and <a href=\"https:\/\/pharmacy.unc.edu\/directory\/ebh\/\"><strong>Emily Harrison<\/strong><\/a>, PhD.<\/p>\n<p>Lung squamous cell cancers comprise up to 30% of all lung cancers and are responsible for about 70,000 new cases and approximately 40,000 deaths each year in the U.S. The results from this study are published in\u00a0<a href=\"https:\/\/cancerres.aacrjournals.org\/\"><em>Cancer Research<\/em><\/a>, a journal of the American Association for Cancer Research.<\/p>\n<figure id=\"attachment_47047\" class=\"thumbnail wp-caption alignright\" style=\"width: 139px\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-47047\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/10\/emily_harrison-2048x2048-2-300x300.jpg\" alt=\"emily_harrison\" width=\"129\" height=\"129\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/10\/emily_harrison-2048x2048-2-300x300.jpg 300w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/10\/emily_harrison-2048x2048-2-1024x1024.jpg 1024w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/10\/emily_harrison-2048x2048-2-150x150.jpg 150w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/10\/emily_harrison-2048x2048-2-768x768.jpg 768w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/10\/emily_harrison-2048x2048-2-1536x1536.jpg 1536w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/10\/emily_harrison-2048x2048-2-600x600.jpg 600w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/10\/emily_harrison-2048x2048-2-301x301.jpg 301w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2020\/10\/emily_harrison-2048x2048-2.jpg 2048w\" sizes=\"auto, (max-width: 129px) 100vw, 129px\" \/><figcaption class=\"caption wp-caption-text\"><span class=\"discreet\">Emily Harrison, PhD<\/span><\/figcaption><\/figure>\n<p>Learn more from the <strong><a href=\"https:\/\/news.unchealthcare.org\/2020\/10\/new-vulnerability-found-in-lung-squamous-cancer-may-facilitate-drug-targeting-at-cellular-level\/\">UNC Health and UNC School of Medicine Newsroom.<\/a><\/strong><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New research by scientists at UNC Lineberger Comprehensive Cancer Center and colleagues shows the potential for targeting a specific circular RNA, known as CDR1as, to attack lung squamous cell cancer. The UNC work was led by Chad Pecot, MD, associate professor of medicine in the division of oncology, and Emily Harrison, PhD. Lung squamous cell &hellip; <a href=\"https:\/\/www.med.unc.edu\/medicine\/news\/new-vulnerability-found-in-lung-squamous-cancer-may-facilitate-drug-targeting-at-cellular-level\/\" aria-label=\"Read more about New Vulnerability Found in Lung Squamous Cancer May Facilitate Drug Targeting at Cellular Level\">Read more<\/a><\/p>\n","protected":false},"author":69419,"featured_media":26777,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,517],"tags":[629],"class_list":["post-47044","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-oncology","tag-629","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>New Vulnerability Found in Lung Squamous Cancer May Facilitate Drug Targeting at Cellular Level | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/new-vulnerability-found-in-lung-squamous-cancer-may-facilitate-drug-targeting-at-cellular-level\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Vulnerability Found in Lung Squamous Cancer May Facilitate Drug Targeting at Cellular Level | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"New research by scientists at UNC Lineberger Comprehensive Cancer Center and colleagues shows the potential for targeting a specific circular RNA, known as CDR1as, to attack lung squamous cell cancer. The UNC work was led by Chad Pecot, MD, associate professor of medicine in the division of oncology, and Emily Harrison, PhD. Lung squamous cell &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/new-vulnerability-found-in-lung-squamous-cancer-may-facilitate-drug-targeting-at-cellular-level\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2020-10-06T19:53:08+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T22:00:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2019\/03\/Pecot-Chad-Faculty-Photo-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1925\" \/>\n\t<meta property=\"og:image:height\" content=\"2560\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Kim Morris\" \/>\n<meta name=\"twitter:card\" 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