{"id":49012,"date":"2021-01-29T12:00:10","date_gmt":"2021-01-29T17:00:10","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=49012"},"modified":"2023-06-06T18:05:17","modified_gmt":"2023-06-06T22:05:17","slug":"hospitalists-study-prognostic-value-of-labs-ordered-for-patients-hospitalized-with-covid-19","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/hospitalists-study-prognostic-value-of-labs-ordered-for-patients-hospitalized-with-covid-19\/","title":{"rendered":"Hospitalists Study Prognostic Value of Labs Ordered For Patients Hospitalized with COVID-19"},"content":{"rendered":"
\"alavian-stern\"
Naseem Alavian, MD, and Elizabeth Stern, MD<\/figcaption><\/figure>\n

Faculty physicians in the division of hospital medicine have assumed most non-intensive care unit care for the coronavirus. Based on sparse research, they developed a protocol for ordering labs for this patient population, including routine admission labs, in addition to eight COVID-19 specific labs. The goal of their recent study, published in Hospital Practice<\/a>, was to determine if COVID-19 specific admission labs have any prognostic value beyond that provided by routine admission labs and vitals, and the costs of labs with no prognostic value.<\/p>\n

Led by Naseem Alavian<\/a>, MD, and Elizabeth Stern<\/a>, MD, both assistant professors in the division of hospital medicine, researchers reviewed adult patients admitted with COVID-19 from 3\/2020 to 7\/2020. Outcomes were mortality, ICU stay, and length of hospitalization. Multivariable logistic and linear regression were used to determine if COVID-19-specific admission labs have any prognostic value beyond that provided by vitals and routine admission labs. COVID-19-specific labs were d-Dimer, fibrinogen, ferritin, LDH, CK, pro-BNP, troponin, and CRP. Multivariable models included all routine admission labs and vitals. COVID-19-specific admission labs were included in the multivariable models if the p-value was <0.05 in the univariable analysis.<\/p>\n

\"Adams-Moore\"
James Sasaki-Adams, MD, and Carleton Moore, MD, MS<\/figcaption><\/figure>\n

The results of the study showed that 331 patients met study criteria, inpatient mortality was 13.0%, 52.4% of patients required ICU stays and the average length of hospitalization was 8.9 days. COVID-19-specific labs showed no additional prognostic value for mortality. CRP, LDH, and d-Dimer provided additional prognostic information for ICU stay. CRP\u2265100 mg\/dL and LDH\u2265900 U\/L were associated with increased length of hospitalization.<\/p>\n

Researchers concluded that only 3 of 8 admission COVID-19-specific labs recommended by UNC Health protocol had additional prognostic value beyond that provided by routine labs and vitals. The total cost of non-prognostic COVID-19-specific labs during the study period was $75,874.<\/p>\n

Hospitalists James Sasaki-Adams<\/a>, MD, assistant professor of medicine, and Carlton Moore<\/a>, MD, MS, professor of medicine and associate chief for research and quality improvement also contributed to the study.<\/p>\n

Find the study here<\/a>.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Faculty physicians in the division of hospital medicine have assumed most non-intensive care unit care for the coronavirus. Based on sparse research, they developed a protocol for ordering labs for this patient population, including routine admission labs, in addition to eight COVID-19 specific labs. The goal of their recent study, published in Hospital Practice, was … Read more<\/a><\/p>\n","protected":false},"author":69419,"featured_media":36130,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[93,2],"tags":[630],"class_list":["post-49012","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hospital-medicine","category-news","tag-630","odd"],"acf":[],"yoast_head":"\nHospitalists Study Prognostic Value of Labs Ordered For Patients Hospitalized with COVID-19 | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/hospitalists-study-prognostic-value-of-labs-ordered-for-patients-hospitalized-with-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hospitalists Study Prognostic Value of Labs Ordered For Patients Hospitalized with COVID-19 | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"Faculty physicians in the division of hospital medicine have assumed most non-intensive care unit care for the coronavirus. 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