{"id":54893,"date":"2021-08-30T16:13:36","date_gmt":"2021-08-30T20:13:36","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=54893"},"modified":"2023-06-06T18:14:08","modified_gmt":"2023-06-06T22:14:08","slug":"emerging-therapies-for-aml-with-myelodysplasia-related-changes-slowly-but-surely-moving-the-needle","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/emerging-therapies-for-aml-with-myelodysplasia-related-changes-slowly-but-surely-moving-the-needle\/","title":{"rendered":"Emerging Therapies For AML With Myelodysplasia-Related Changes: Slowly But Surely Moving the Needle"},"content":{"rendered":"<figure id=\"attachment_54895\" class=\"thumbnail wp-caption alignright\" style=\"width: 310px\"><a href=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2021\/08\/davis-phillips-josh-zeidner.png\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-54895\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2021\/08\/davis-phillips-josh-zeidner-300x206.png\" alt=\"davis-phillips-josh-zeidner\" width=\"300\" height=\"206\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2021\/08\/davis-phillips-josh-zeidner-300x206.png 300w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2021\/08\/davis-phillips-josh-zeidner-768x529.png 768w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2021\/08\/davis-phillips-josh-zeidner-600x413.png 600w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2021\/08\/davis-phillips-josh-zeidner-301x207.png 301w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2021\/08\/davis-phillips-josh-zeidner.png 898w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption class=\"caption wp-caption-text\">David Phillips, MD, and Josh Zeidner, MD<\/figcaption><\/figure>\n<p>Patients with acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) have historically poor outcomes with conventional chemotherapy regimens.<\/p>\n<p><a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/davis-phillips-md-jd\/\">Davis Phillips<\/a>, MD, internal medicine resident, and <a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/joshua-zeidner-md\/\">Josh Zeidner<\/a>, MD, associate professor of medicine in the division of hematology, published an article that\u00a0reviews the data for existing therapeutic options for patients with AML-MRC and the emerging therapies undergoing clinical trial development for this patient population. The authors conclude that clinical trials focused specifically on this patient population are urgently needed.<\/p>\n<p><a href=\"https:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/14728214.2021.1950689?scroll=top&amp;needAccess=true&amp;journalCode=iemd20\">Read the article published in <\/a><a href=\"https:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/14728214.2021.1950689?scroll=top&amp;needAccess=true&amp;journalCode=iemd20\"><em>Expert Opinion on Emerging Drugs.<\/em><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Patients with acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) have historically poor outcomes with conventional chemotherapy regimens. Davis Phillips, MD, internal medicine resident, and Josh Zeidner, MD, associate professor of medicine in the division of hematology, published an article that\u00a0reviews the data for existing therapeutic options for patients with AML-MRC and the emerging therapies undergoing &hellip; <a href=\"https:\/\/www.med.unc.edu\/medicine\/news\/emerging-therapies-for-aml-with-myelodysplasia-related-changes-slowly-but-surely-moving-the-needle\/\" aria-label=\"Read more about Emerging Therapies For AML With Myelodysplasia-Related Changes: Slowly But Surely Moving the Needle\">Read more<\/a><\/p>\n","protected":false},"author":69419,"featured_media":54895,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[520,2,583],"tags":[630],"class_list":["post-54893","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hematology","category-news","category-research-news","tag-630","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Emerging Therapies For AML With Myelodysplasia-Related Changes: Slowly But Surely Moving the Needle | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/emerging-therapies-for-aml-with-myelodysplasia-related-changes-slowly-but-surely-moving-the-needle\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Emerging Therapies For AML With Myelodysplasia-Related Changes: Slowly But Surely Moving the Needle | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"Patients with acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) have historically poor outcomes with conventional chemotherapy regimens. Davis Phillips, MD, internal medicine resident, and Josh Zeidner, MD, associate professor of medicine in the division of hematology, published an article that\u00a0reviews the data for existing therapeutic options for patients with AML-MRC and the emerging therapies undergoing &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/emerging-therapies-for-aml-with-myelodysplasia-related-changes-slowly-but-surely-moving-the-needle\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2021-08-30T20:13:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T22:14:08+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2021\/08\/davis-phillips-josh-zeidner.png\" \/>\n\t<meta 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