{"id":54921,"date":"2021-08-30T20:37:24","date_gmt":"2021-08-31T00:37:24","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=54921"},"modified":"2023-06-06T18:14:17","modified_gmt":"2023-06-06T22:14:17","slug":"chemotherapy-plus-immunotherapy-before-surgery-is-beneficial-for-invasive-bladder-cancer-outcomes","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/chemotherapy-plus-immunotherapy-before-surgery-is-beneficial-for-invasive-bladder-cancer-outcomes\/","title":{"rendered":"Chemotherapy Plus Immunotherapy Before Surgery is Beneficial For Invasive Bladder Cancer Outcomes"},"content":{"rendered":"<figure id=\"attachment_6795\" class=\"thumbnail wp-caption alignright\" style=\"width: 273px\"><a href=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-scaled.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-6795\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-263x300.jpg\" alt=\"Rose_LCCC_Headshot\" width=\"263\" height=\"300\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-263x300.jpg 263w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-897x1024.jpg 897w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-768x877.jpg 768w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-1346x1536.jpg 1346w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-1794x2048.jpg 1794w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-600x685.jpg 600w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-301x344.jpg 301w\" sizes=\"auto, (max-width: 263px) 100vw, 263px\" \/><\/a><figcaption class=\"caption wp-caption-text\">Tracy Rose, MD, MPH<\/figcaption><\/figure>\n<p>A new study is the first to report the beneficial use of chemotherapy plus immunotherapy before surgical removal of the bladder in muscle-invasive bladder cancer (MIBC). Researchers at the UNC Lineberger Comprehensive Cancer Center led the study, reporting that the regimen reduced the invasiveness of the cancer in 56 percent of patients in a phase II clinical trial.<\/p>\n<p>The findings were published in the <a href=\"https:\/\/ascopubs.org\/doi\/abs\/10.1200\/JCO.21.01003\">Journal of Clinical Oncology<\/a>.<\/p>\n<p>\u201cDownstaging, or treating tumors so that they become less invasive prior to surgical removal, is an important tool in muscle-invasive bladder cancer,\u201d said UNC Lineberger\u2019s <a href=\"https:\/\/unclineberger.org\/directory\/tracy-l-rose\/\">Tracy Rose, MD, MPH<\/a>, assistant professor at the UNC School of Medicine and lead author of this finding. \u201cIf we can treat a tumor pre-surgically so that it regresses to a stage where it is superficial and does not invade the bladder muscle wall, the chances of long-term survival are better.\u201d<\/p>\n<p>Read more from the <a href=\"https:\/\/unclineberger.org\/news\/chemotherapy-plus-immunotherapy-before-surgery-is-beneficial-for-invasive-bladder-cancer-outcomes\/\">UNC Lineberger Newsroom.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study is the first to report the beneficial use of chemotherapy plus immunotherapy before surgical removal of the bladder in muscle-invasive bladder cancer (MIBC). Researchers at the UNC Lineberger Comprehensive Cancer Center led the study, reporting that the regimen reduced the invasiveness of the cancer in 56 percent of patients in a phase &hellip; <a href=\"https:\/\/www.med.unc.edu\/medicine\/news\/chemotherapy-plus-immunotherapy-before-surgery-is-beneficial-for-invasive-bladder-cancer-outcomes\/\" aria-label=\"Read more about Chemotherapy Plus Immunotherapy Before Surgery is Beneficial For Invasive Bladder Cancer Outcomes\">Read more<\/a><\/p>\n","protected":false},"author":69419,"featured_media":6795,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,517,583],"tags":[630],"class_list":["post-54921","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-oncology","category-research-news","tag-630","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Chemotherapy Plus Immunotherapy Before Surgery is Beneficial For Invasive Bladder Cancer Outcomes | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/chemotherapy-plus-immunotherapy-before-surgery-is-beneficial-for-invasive-bladder-cancer-outcomes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chemotherapy Plus Immunotherapy Before Surgery is Beneficial For Invasive Bladder Cancer Outcomes | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"A new study is the first to report the beneficial use of chemotherapy plus immunotherapy before surgical removal of the bladder in muscle-invasive bladder cancer (MIBC). Researchers at the UNC Lineberger Comprehensive Cancer Center led the study, reporting that the regimen reduced the invasiveness of the cancer in 56 percent of patients in a phase &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/chemotherapy-plus-immunotherapy-before-surgery-is-beneficial-for-invasive-bladder-cancer-outcomes\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2021-08-31T00:37:24+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T22:14:17+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/Rose_LCCC_Headshot-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2243\" \/>\n\t<meta property=\"og:image:height\" content=\"2560\" 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