{"id":58005,"date":"2022-01-30T20:23:37","date_gmt":"2022-01-31T01:23:37","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=58005"},"modified":"2023-06-06T18:18:16","modified_gmt":"2023-06-06T22:18:16","slug":"hemoglobin-glycation-index-calculated-from-a-single-fasting-glucose-value-as-a-prediction-tool-for-severe-hypoglycemia-and-major-adverse-cardiovascular-events-in-devote","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/hemoglobin-glycation-index-calculated-from-a-single-fasting-glucose-value-as-a-prediction-tool-for-severe-hypoglycemia-and-major-adverse-cardiovascular-events-in-devote\/","title":{"rendered":"Hemoglobin Glycation Index, Calculated From a Single Fasting Glucose Value, as a Prediction Tool for Severe Hypoglycemia and Major Adverse Cardiovascular Events in DEVOTE"},"content":{"rendered":"<figure id=\"attachment_6453\" class=\"thumbnail wp-caption alignright\" style=\"width: 224px\"><a href=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-6453\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara-214x300.jpg\" alt=\"KleinKlara-BMJ-Open-Diabetes-Res-Care\" width=\"214\" height=\"300\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara-214x300.jpg 214w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara-731x1024.jpg 731w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara-768x1075.jpg 768w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara-1097x1536.jpg 1097w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara-1463x2048.jpg 1463w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara-600x840.jpg 600w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara-301x421.jpg 301w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara.jpg 1500w\" sizes=\"auto, (max-width: 214px) 100vw, 214px\" \/><\/a><figcaption class=\"caption wp-caption-text\">Klara Klein, MD, PhD<\/figcaption><\/figure>\n<p><a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/klara-klein\/\">Klara R. Klein<\/a>, MD, PhD, fellow in the division of endocrinology and metabolism and trainee in the UNC\u00a0Physician Scientist Training Program, and <a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/john-buse-md-phd\/\">John Buse<\/a>, MD, PhD, chief of the division of endocrinology and metabolism, are authors of a new study published in <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34819298\/\"><em>BMJ Open Diabetes Research and Care<\/em><\/a>.<\/p>\n<p>Hemoglobin glycation index is the difference between observed and predicted glycated hemoglobin A1c, derived from mean or fasting plasma glucose. In this secondary, exploratory analysis of data from DEVOTE, Klein and team examined whether insulin initiation\/titration affected the HGI; the relationship between baseline HGI tertile and cardiovascular and hypoglycemia risk; and the relative strengths of HGI and HbA1c in predicting these risks.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34819298\/\">Learn more about the study<\/a>.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Klara R. Klein, MD, PhD, fellow in the division of endocrinology and metabolism and trainee in the UNC\u00a0Physician Scientist Training Program, and John Buse, MD, PhD, chief of the division of endocrinology and metabolism, are authors of a new study published in BMJ Open Diabetes Research and Care. Hemoglobin glycation index is the difference between &hellip; <a href=\"https:\/\/www.med.unc.edu\/medicine\/news\/hemoglobin-glycation-index-calculated-from-a-single-fasting-glucose-value-as-a-prediction-tool-for-severe-hypoglycemia-and-major-adverse-cardiovascular-events-in-devote\/\" aria-label=\"Read more about Hemoglobin Glycation Index, Calculated From a Single Fasting Glucose Value, as a Prediction Tool for Severe Hypoglycemia and Major Adverse Cardiovascular Events in DEVOTE\">Read more<\/a><\/p>\n","protected":false},"author":69419,"featured_media":6453,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[96,2,583],"tags":[631],"class_list":["post-58005","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-endocrinology-metabolism","category-news","category-research-news","tag-631","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hemoglobin Glycation Index, Calculated From a Single Fasting Glucose Value, as a Prediction Tool for Severe Hypoglycemia and Major Adverse Cardiovascular Events in DEVOTE | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/hemoglobin-glycation-index-calculated-from-a-single-fasting-glucose-value-as-a-prediction-tool-for-severe-hypoglycemia-and-major-adverse-cardiovascular-events-in-devote\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hemoglobin Glycation Index, Calculated From a Single Fasting Glucose Value, as a Prediction Tool for Severe Hypoglycemia and Major Adverse Cardiovascular Events in DEVOTE | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"Klara R. Klein, MD, PhD, fellow in the division of endocrinology and metabolism and trainee in the UNC\u00a0Physician Scientist Training Program, and John Buse, MD, PhD, chief of the division of endocrinology and metabolism, are authors of a new study published in BMJ Open Diabetes Research and Care. Hemoglobin glycation index is the difference between &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/hemoglobin-glycation-index-calculated-from-a-single-fasting-glucose-value-as-a-prediction-tool-for-severe-hypoglycemia-and-major-adverse-cardiovascular-events-in-devote\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2022-01-31T01:23:37+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T22:18:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/KleinKlara.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1500\" \/>\n\t<meta property=\"og:image:height\" content=\"2100\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" 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