{"id":60353,"date":"2022-07-19T10:51:19","date_gmt":"2022-07-19T14:51:19","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=60353"},"modified":"2023-06-06T18:20:50","modified_gmt":"2023-06-06T22:20:50","slug":"drs-gang-xi-and-prabir-roy-chaudhury-receive-2-7-million-grant-from-the-national-institute-of-diabetes-and-digestive-and-kidney-diseases","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/drs-gang-xi-and-prabir-roy-chaudhury-receive-2-7-million-grant-from-the-national-institute-of-diabetes-and-digestive-and-kidney-diseases\/","title":{"rendered":"Drs. Gang Xi and Prabir Roy-Chaudhury Receive $2.7 Million Grant from the National Institute of Diabetes and Digestive and Kidney Diseases\u00a0"},"content":{"rendered":"<figure id=\"attachment_60356\" class=\"thumbnail wp-caption alignright\" style=\"width: 310px\"><a href=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/07\/Untitled-design.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-60356 size-medium\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/07\/Untitled-design-300x300.jpg\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/07\/Untitled-design-300x300.jpg 300w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/07\/Untitled-design-150x150.jpg 150w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/07\/Untitled-design-301x301.jpg 301w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/07\/Untitled-design.jpg 500w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption class=\"caption wp-caption-text\">Gang Xi, PhD and Prabir Roy-Chaudhury, MD, PhD, FRCP(Edin)<\/figcaption><\/figure>\n<p style=\"font-weight: 400\"><a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/gang-xi-phd\/\">Dr. Gang Xi<\/a>, assistant professor in the <a href=\"https:\/\/www.med.unc.edu\/medicine\/nephrology-hypertension\">Division of Nephrology and Hypertension<\/a>, and <a href=\"https:\/\/www.med.unc.edu\/medicine\/directory\/prabir-roy-chaudhury\/\">Dr. Prabir Roy-Chaudhury<\/a>, professor in the Division of Nephrology and Hypertension and co-driector of the UNC Kidney Center, were recently awarded a, five year, $2.7 million grant. Their project titled, &#8220;Modulation of VSMC phenotype through the Insulin Receptor Substrate 1\/Kruppel-like factor-4 signal transduction pathway: a Novel Target for AVF Dysfunction,&#8221; will be funded by the National Institute of Diabetes and Digestive and Kidney Diseases\u00a0(NIDDK).<\/p>\n<p style=\"font-weight: 400\">The researchers aim to study Vascular Smooth Muscle Cell (VSMC)\u00a0phenotype switching in the setting of arteriovenous fistula maturation failure in an attempt to develop new therapies for this important clinical problem. Other members of the multi-disciplinary team include Drs. Boyce Griffith, Yueh Lee, Hong Yuan, Uni Uriyanghai, as well as Christine Wai.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Gang Xi, assistant professor in the Division of Nephrology and Hypertension, and Dr. Prabir Roy-Chaudhury, professor in the Division of Nephrology and Hypertension and co-driector of the UNC Kidney Center, were recently awarded a, five year, $2.7 million grant. Their project titled, &#8220;Modulation of VSMC phenotype through the Insulin Receptor Substrate 1\/Kruppel-like factor-4 signal &hellip; <a href=\"https:\/\/www.med.unc.edu\/medicine\/news\/drs-gang-xi-and-prabir-roy-chaudhury-receive-2-7-million-grant-from-the-national-institute-of-diabetes-and-digestive-and-kidney-diseases\/\" aria-label=\"Read more about Drs. Gang Xi and Prabir Roy-Chaudhury Receive $2.7 Million Grant from the National Institute of Diabetes and Digestive and Kidney Diseases\u00a0\">Read more<\/a><\/p>\n","protected":false},"author":112673,"featured_media":60356,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[101,2],"tags":[631],"class_list":["post-60353","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nephrology","category-news","tag-631","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Drs. 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Gang Xi and Prabir Roy-Chaudhury Receive $2.7 Million Grant from the National Institute of Diabetes and Digestive and Kidney Diseases\u00a0 | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"Dr. Gang Xi, assistant professor in the Division of Nephrology and Hypertension, and Dr. Prabir Roy-Chaudhury, professor in the Division of Nephrology and Hypertension and co-driector of the UNC Kidney Center, were recently awarded a, five year, $2.7 million grant. Their project titled, &#8220;Modulation of VSMC phenotype through the Insulin Receptor Substrate 1\/Kruppel-like factor-4 signal &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/drs-gang-xi-and-prabir-roy-chaudhury-receive-2-7-million-grant-from-the-national-institute-of-diabetes-and-digestive-and-kidney-diseases\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2022-07-19T14:51:19+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T22:20:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/07\/Untitled-design.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"500\" \/>\n\t<meta property=\"og:image:height\" content=\"500\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Morgan Duerden\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@uncdeptmedicine\" \/>\n<meta name=\"twitter:site\" content=\"@uncdeptmedicine\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Morgan Duerden\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/drs-gang-xi-and-prabir-roy-chaudhury-receive-2-7-million-grant-from-the-national-institute-of-diabetes-and-digestive-and-kidney-diseases\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/drs-gang-xi-and-prabir-roy-chaudhury-receive-2-7-million-grant-from-the-national-institute-of-diabetes-and-digestive-and-kidney-diseases\/\"},\"author\":{\"name\":\"Morgan Duerden\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/#\/schema\/person\/99bd6d3f6c7b07d9e318254957f14bf9\"},\"headline\":\"Drs. 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