{"id":60469,"date":"2022-08-02T11:16:50","date_gmt":"2022-08-02T15:16:50","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=60469"},"modified":"2023-06-06T18:21:11","modified_gmt":"2023-06-06T22:21:11","slug":"study-shows-the-positive-effect-of-preventative-therapy-for-malaria-is-mediated-by-gestational-weight-gain-influenced-by-intestinal-pathogens","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/study-shows-the-positive-effect-of-preventative-therapy-for-malaria-is-mediated-by-gestational-weight-gain-influenced-by-intestinal-pathogens\/","title":{"rendered":"Study shows the positive effect of preventative therapy for malaria is mediated by gestational weight gain, influenced by intestinal pathogens"},"content":{"rendered":"<figure id=\"attachment_60470\" class=\"thumbnail wp-caption alignright\" style=\"width: 310px\"><a href=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/08\/waltmann-meshnick-scaled-e1656101391554-1024x793-1.jpeg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-60470 size-medium\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/08\/waltmann-meshnick-scaled-e1656101391554-1024x793-1-300x232.jpeg\" alt=\"waltmann-meshnick-scaled-e1656101391554-1024x793\" width=\"300\" height=\"232\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/08\/waltmann-meshnick-scaled-e1656101391554-1024x793-1-300x232.jpeg 300w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/08\/waltmann-meshnick-scaled-e1656101391554-1024x793-1-768x595.jpeg 768w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/08\/waltmann-meshnick-scaled-e1656101391554-1024x793-1-600x465.jpeg 600w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/08\/waltmann-meshnick-scaled-e1656101391554-1024x793-1-301x233.jpeg 301w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/08\/waltmann-meshnick-scaled-e1656101391554-1024x793-1.jpeg 1024w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><figcaption class=\"caption wp-caption-text\">Andreea Waltmann and the late Steve Meshnick.<\/figcaption><\/figure>\n<p>Malaria in pregnancy (MiP) is a major public health problem with substantial risks for mothers and their babies. The combination treatment sulfadoxine-pyrimethamine (SP), given for\u00a0<a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/intermittent-preventive-therapy\">intermittent preventive therapy<\/a>\u00a0of malaria in pregnancy (IPTp), is one of the few existing interventions that improve outcomes for both mother and baby, despite widespread SP-resistant malaria. Compelling evidence has shown malaria-independent pathways contribute to the protective effects, but how non-malaria pathways provide protection is not known.<\/p>\n<p><a href=\"https:\/\/globalhealth.unc.edu\/2022\/06\/study-shows-the-positive-effect-of-preventative-therapy-for-malaria-is-mediated-by-gestational-weight-gain-influenced-by-intestinal-pathogens\/\">Read more<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Malaria in pregnancy (MiP) is a major public health problem with substantial risks for mothers and their babies. The combination treatment sulfadoxine-pyrimethamine (SP), given for\u00a0intermittent preventive therapy\u00a0of malaria in pregnancy (IPTp), is one of the few existing interventions that improve outcomes for both mother and baby, despite widespread SP-resistant malaria. Compelling evidence has shown malaria-independent &hellip; <a href=\"https:\/\/www.med.unc.edu\/medicine\/news\/study-shows-the-positive-effect-of-preventative-therapy-for-malaria-is-mediated-by-gestational-weight-gain-influenced-by-intestinal-pathogens\/\" aria-label=\"Read more about Study shows the positive effect of preventative therapy for malaria is mediated by gestational weight gain, influenced by intestinal pathogens\">Read more<\/a><\/p>\n","protected":false},"author":69419,"featured_media":60470,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[640,100,2,583],"tags":[631],"class_list":["post-60469","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fellowship","category-infectious-diseases","category-news","category-research-news","tag-631","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Study shows the positive effect of preventative therapy for malaria is mediated by gestational weight gain, influenced by intestinal pathogens | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/study-shows-the-positive-effect-of-preventative-therapy-for-malaria-is-mediated-by-gestational-weight-gain-influenced-by-intestinal-pathogens\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study shows the positive effect of preventative therapy for malaria is mediated by gestational weight gain, influenced by intestinal pathogens | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"Malaria in pregnancy (MiP) is a major public health problem with substantial risks for mothers and their babies. The combination treatment sulfadoxine-pyrimethamine (SP), given for\u00a0intermittent preventive therapy\u00a0of malaria in pregnancy (IPTp), is one of the few existing interventions that improve outcomes for both mother and baby, despite widespread SP-resistant malaria. Compelling evidence has shown malaria-independent &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/study-shows-the-positive-effect-of-preventative-therapy-for-malaria-is-mediated-by-gestational-weight-gain-influenced-by-intestinal-pathogens\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2022-08-02T15:16:50+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-06T22:21:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2022\/08\/waltmann-meshnick-scaled-e1656101391554-1024x793-1.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"793\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Kim Morris\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@uncdeptmedicine\" \/>\n<meta name=\"twitter:site\" content=\"@uncdeptmedicine\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Kim Morris\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/study-shows-the-positive-effect-of-preventative-therapy-for-malaria-is-mediated-by-gestational-weight-gain-influenced-by-intestinal-pathogens\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/medicine\/news\/study-shows-the-positive-effect-of-preventative-therapy-for-malaria-is-mediated-by-gestational-weight-gain-influenced-by-intestinal-pathogens\/\"},\"author\":{\"name\":\"Kim 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