Cassandra Donahue<\/a>, research coordinator, and Julie Uehling, research coordinator, enrolled and examined 34 participants over several years. The recently released results showed those treated with Wegovy had a 20% lower risk of experiencing a MACE compared to the placebo group.<\/p>\n\u201cWhile these results are only a preliminary press release primarily intended to minimize rumors in financial markets, the SELECT trial changes weight loss therapy from something that many people want to something with clear cut benefits on \u201chard\u201d outcomes like heart attack, stroke and cardiovascular death,\u201d Dr. Buse said. \u201cThat is a first for any weight loss treatment trial to date and should change the conversation about weight loss to one focused on the health benefits and not cosmetic changes.\u201d<\/p>\n
All three components of MACE \u2013 cardiovascular death, non-fatal heart attack and non-fatal stroke \u2013 contributed to the overall reduction in risk seen with Wegovy. With currently no approved medications that effectively manage weight and reduce cardiovascular risks, Wegovy is expected to make a large impact.<\/p>\n
Novo Nordisk announced their plans to seek regulatory approvals to expand the use of semaglutide 2.4 mg (marketed as Wegovy\u00ae) in the US and the EU based on these positive results. The detailed findings from the trial will be presented at a scientific conference later in the year.<\/p>\n
\n
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A new study shows semaglutide 2.4 mg (Wegovy), a weekly injected prescription medication for overweight adults, may prevent major adverse cardiovascular events (MACEs) such as cardiovascular death, non-fatal heart attack or non-fatal stroke. Novo Nordisk released the results of the significant clinical trial called SELECT. The trail studied the effects of Wegovy on people with … Read more<\/a><\/p>\n","protected":false},"author":112673,"featured_media":3663,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[96,2,583],"tags":[632],"class_list":["post-65446","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-endocrinology-metabolism","category-news","category-research-news","tag-632","odd"],"acf":[],"yoast_head":"\nStudy Shows Weight Loss Drug Reduces Cardiovascular Risk by 20% in Overweight, Obese Adults | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/study-shows-weight-loss-drug-reduces-cardiovascular-risk-by-20-in-overweight-obese-adults\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study Shows Weight Loss Drug Reduces Cardiovascular Risk by 20% in Overweight, Obese Adults | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"A new study shows semaglutide 2.4 mg (Wegovy), a weekly injected prescription medication for overweight adults, may prevent major adverse cardiovascular events (MACEs) such as cardiovascular death, non-fatal heart attack or non-fatal stroke. 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