{"id":67851,"date":"2024-07-11T10:34:43","date_gmt":"2024-07-11T14:34:43","guid":{"rendered":"https:\/\/www.med.unc.edu\/medicine\/?p=67851"},"modified":"2024-07-11T10:34:43","modified_gmt":"2024-07-11T14:34:43","slug":"dr-lara-longobardi-receives-r01-renewal-from-nih-to-study-the-role-of-ccr2-in-osteoarthritis","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/medicine\/news\/dr-lara-longobardi-receives-r01-renewal-from-nih-to-study-the-role-of-ccr2-in-osteoarthritis\/","title":{"rendered":"Dr. Lara Longobardi Receives R01 Renewal from NIH to Study the Role of CCR2 in Osteoarthritis"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-7257 alignright\" src=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/lara-longobardi-702x1024.jpg\" alt=\"\" width=\"225\" height=\"328\" srcset=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/lara-longobardi-702x1024.jpg 702w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/lara-longobardi-206x300.jpg 206w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/lara-longobardi-768x1119.jpg 768w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/lara-longobardi-600x875.jpg 600w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/lara-longobardi-301x439.jpg 301w, https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/lara-longobardi.jpg 1051w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><a href=\"https:\/\/www.med.unc.edu\/medicine\/rheumatology-allergy-immunology\/people\/lara-longobardi-phd\/\">Lara Longobardi, PhD,\u00a0<\/a>associate professor of medicine in the Division on Rheumatology, Allergy and Immunology, recently received funding through the National Institute of Health (NIH); National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) for the renewal of her R01.<\/p>\n<p>The project, <strong>\u201cRole of CCR2 in osteoarthritis\u201d, <\/strong>will establish the molecular events leading to the multi tissue OA degeneration and macrophage activation induced by CCR2 and how they correlate to pain and muscle damage; in addition, the study will test two novel and efficient drug delivery systems to target tissues, local and systemic, avoiding extended high-dose exposure while protecting it from degradation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lara Longobardi, PhD,\u00a0associate professor of medicine in the Division on Rheumatology, Allergy and Immunology, recently received funding through the National Institute of Health (NIH); National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) for the renewal of her R01. The project, \u201cRole of CCR2 in osteoarthritis\u201d, will establish the molecular events leading to the &hellip; <a href=\"https:\/\/www.med.unc.edu\/medicine\/news\/dr-lara-longobardi-receives-r01-renewal-from-nih-to-study-the-role-of-ccr2-in-osteoarthritis\/\" aria-label=\"Read more about Dr. Lara Longobardi Receives R01 Renewal from NIH to Study the Role of CCR2 in Osteoarthritis\">Read more<\/a><\/p>\n","protected":false},"author":112673,"featured_media":7257,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2,644,583,103],"tags":[673],"class_list":["post-67851","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-research-funding","category-research-news","category-rheumatology","tag-673","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dr. Lara Longobardi Receives R01 Renewal from NIH to Study the Role of CCR2 in Osteoarthritis | Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/medicine\/news\/dr-lara-longobardi-receives-r01-renewal-from-nih-to-study-the-role-of-ccr2-in-osteoarthritis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dr. Lara Longobardi Receives R01 Renewal from NIH to Study the Role of CCR2 in Osteoarthritis | Department of Medicine\" \/>\n<meta property=\"og:description\" content=\"Lara Longobardi, PhD,\u00a0associate professor of medicine in the Division on Rheumatology, Allergy and Immunology, recently received funding through the National Institute of Health (NIH); National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) for the renewal of her R01. The project, \u201cRole of CCR2 in osteoarthritis\u201d, will establish the molecular events leading to the &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/medicine\/news\/dr-lara-longobardi-receives-r01-renewal-from-nih-to-study-the-role-of-ccr2-in-osteoarthritis\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/UNCDeptMedicine\" \/>\n<meta property=\"article:published_time\" content=\"2024-07-11T14:34:43+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/medicine\/wp-content\/uploads\/sites\/945\/2018\/12\/lara-longobardi.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1051\" \/>\n\t<meta property=\"og:image:height\" content=\"1532\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Morgan Duerden\" \/>\n<meta name=\"twitter:card\" 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