The MHI Cardiovascular Physiology and Phenotyping Core provides a variety of established and experiment-specific animal surgical/microsurgical models for a broad range of research applications, with the primary function of meeting investigator needs. The Core Director and staff have extensive experience with mouse, rat, and other animal surgical and microsurgical models across many disciplines. The Core focuses on murine models which have become a predominant tool for many research labs; models in other species are also done and offered through arrangement, with applications from invertebrates to primates. The surgical services are flexible, from straightforward single-procedure surgeries (with return to PI labs for subsequent follow-up/analysis), to complete surgical/postoperative management and final analysis with humane euthanasia. Approved IACUC protocols are in place for established models offered by the Core. Please contact the Core Director with any questions.
Models of Congestive Heart Failure
Models of Ischemic Heart Injury
Intravital Fluorescence Imaging of Thrombosis