MHI Seminar Series: Lilei Zhang, Ph.D., M.D., “Circadian Regulation in Cardiac Remodeling”
2023-09-13 10:30 - 11:30 (America/New_York) | 1131 Bioinformatics Building, 130 Mason Farm Rd., Chapel Hill, NC, 27514, United States

MHI Seminar Series: Rebekah Gundry, Ph.D., “Heart of Innovation: Revolutionizing the Study of Glycoproteins in Heart Health and Disease with Advanced Technologies”
2023-10-18 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States

MHI Seminar Series: Ching-Ling (Ellen) Lien, Ph.D., “Cardiac Vasculature in Heart Development and Regeneration”
2023-11-15 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States

MHI Seminar Series: Walter Lee Murfee, III, Ph.D., “Rediscovering Angiogenesis at the Intersection of Tissue Engineering and Physiology”
2023-12-06 10:00 - 11:00 | 1131 Bioinformatics Building, 130 Mason Farm Rd., Chapel Hill, NC, 27514, United States

MHI Faculty Candidate Seminar: Ching Zhu, M.D., Ph.D., “Neural Control of Cardiac Arrhythmia Susceptibility: Patterns and Mechanisms”
2024-01-05 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States

MHI Seminar Series: Nadia Mercader, Ph.D., Professor, Developmental Biology and Regeneration, Institute of Anatomy, University of Bern, Bern, Switzerland
2024-01-17 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States

CANCELLED: MHI Seminar Series: Stefania Nicoli, Ph.D., Associate Professor Tenure; Director of the Zebrafish Phenotyping Core for Precision Medicine, Internal Medicine and Genetics; Co-Director, Yale Cardiovascular Research Center (YCVRC), Yale School of Medicine-Yale University, New Haven, CT
2024-02-14 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States

2024 IVB/MHI Annual Research Symposium
2024-03-13 09:00 - 18:00 | NC
Maya Kumar, PhD
Assistant Professor, Pediatrics/Pulmonary Medicine
Stanford University School of Medicine
“Using single cell approaches to understand neointimal lesion formation and growth in Pulmonary Hypertension”

Hanjoong Jo, PhD
Professor, Biomedical Engineering, Georgia Tech and Emory University
“Flow-induced reprogramming of endothelial cells and atherosclerosis – role of HEG1”

MHI Seminar Series: MHI Keynote Speaker - Hanjoong Jo, Ph.D., Wallace H. Coulter Distinguished Professor, Coulter Department of Biomedical Engineering; Associate Chair-Emory; Director of Cardiovascular Biomechanics T32 Program-Emory & Georgia Tech (GT), Emory University/GT
2024-03-13 12:30 - 13:30 | The Carolina Club, George Watts Alumni Center, 150 Stadium Drive, Chapel Hill, NC, 27514

MHI SEMINAR SERIES: Mingfu Wu, Ph.D., Associate Professor, Pharmacology, Department of Pharmacological and Pharmaceutical Sciences, University of Houston
2024-03-20 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States
RESEARCH: My lab aims to determine the etiology and then the treatment for the left ventricular non-compaction cardiomyopathy. 2. Another project will determine how epicardial development regulates cardiac morphogenesis and explore methods to treat congenital heart defects caused by abnormal epicardial development. 3. We are also screening chemicals that promote cardiomyocyte maturation during cell-reprogramming and cardiomyocyte proliferation during cardiac regeneration.

MHI Seminar Series: Mingfu Wu, Ph.D., Associate Professor, Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Texas
2024-03-20 10:00 - 11:00 | Macnider Hall, Conference Room 321, 333 S. Columbia St., Chapel Hill, NC, 27514, United States

MHI SEMINAR SERIES: Jonathan Brown, M.D., Associate Professor, Medicine, Cardiovascular Medicine at Vanderbilt University
2024-04-17 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States
Jonathan Brown, MD, is a cardiologist and basic scientist studying transcriptional mechanisms relevant to the pathogenesis of obesity, diabetes mellitus, and atherosclerosis. A central premise of his research involves a deeper understanding of the gene regulatory networks controlling disease pathogenesis to identify novel therapeutic targets to treat these prevalent and often fatal conditions.
More specifically, Dr. Brown aims to study how chromatin regulators—as determinants of enhancer function and transcription—are involved in driving pathologic gene expression programs that alter vascular cell and adipose tissue function and result in cardiovascular disease and metabolic dysfunction. Because of his interest in the interplay among inflammation, metabolic disease, and atherogenesis, he is pursuing overlapping areas of investigation examining: how proinflammatory activation of vascular endothelium and macrophages drives enhancer remodeling and gene activation through the bromodomain and extra-terminal (BET) bromodomain proteins (BRD2, BRD3 and BRD4); and how BET proteins control adipocyte plasticity and differentiation relevant for obesity and systemic metabolic diseases.
Dr. Brown’s areas of expertise are general cardiology, preventive cardiology, and management of hyperlipidemia.

MHI Seminar Series: Jonathan Brown, M.D., Associate Professor of Medicine; Riven Family Director of Experimental Biology, Division of Cardiovascular Medicine, Vanderbilt University Medical Center
2024-04-17 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States

Rong Wang, Ph.D., Professor of Surgery, Director, Laboratory for Accelerated Vascular Research, UCSF
2024-04-24 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States
Research Overview:

MOLECULAR PROGRAMMING OF THE VASCULATURE IN DEVELOPMENT AND DISEASE
Proper formation and function of the vasculature are crucial for health and survival, as the vasculature supplies all cells in the body. A dysfunctional vasculature causes myriad diseases, including stroke, arterial occlusive diseases, and vascular anomalies. Our long-term goal is to identify novel drug targets and inform rational therapeutic designs to treat vascular diseases. Our strategy is to understand genes crucial for angiogenesis (new vessel formation) in the normal and diseased states, concentrating on the Notch, ephrin-B2, and TGF- pathways. We employ cutting-edge mouse genetics to delete or express genes in a cell lineage-specific and temporally controllable fashion in vascular cells. We combine these molecular approaches with mouse models of diseases as well as live 5D two-photon imaging (3D + blood flow over time) to uncover both the molecular mechanisms and hemodynamic signals in development and disease progression. These preclinical animal studies are coupled with patient sample validations. Our lab members come from diverse fields, including biology, bioengineering, and medicine, creating a collaborative and exciting environment. We strive to advance multiple projects across disciplines.

MHI Seminar Series: Rong Wang, Ph.D., Professor, Surgery, Division of Vascular and Endovascular Surgery; Mildred V. Strouss Endowed Chair in Vascular Surgery; Director, Laboratory for Accelerated Vascular Research, University of California, San Francisco
2024-04-24 10:00 - 11:00 | 321 MacNider Hall, 333 S Columbia St., Chapel Hill, NC, 27514, United States

MHI SEMINAR SERIES: Karen Hirschi, Ph.D., Professor, Cell Biology, Director, UVA Developmental Genomics Center, University of Virginia
2024-05-01 10:00 - 11:00 | 1131 Bioinformatics Building, 130 Mason Farm Rd., Chapel Hill, NC, 27514, United States
Research Interest: Our laboratory is specifically interested in the regulation of endothelial cell commitment, differentiation and cell cycle progression, and defining signaling pathways that modulate these processes. We also aim to understand how some endothelial cells acquire specialized functions, such as the generation and/or maintenance of multi-lineage stem/progenitor cells.

2024 Fall Seminar Series to Kick off in September
2024-09-18 10:00 - 11:00 | Lineberger Comprehensive Cancer Center, Pagano Conference Room 00-002, 450 West Dr., Chapel Hill, NC, 27599, United States
Yosuke Mukoyama, Ph.D.

Senior Investigator, Lab Stem Cell and Neurovascular Biology Cell and Developmental Biology Center, NHLBI/NHI, Bethesda, MD
The overarching goal of the Laboratory of Stem Cell and Neurovascular Research, led by Dr. Yosuke Mukoyama (Yoh‐suke Mukouyama in PubMed), is to uncover the molecular control of the morphologic processes underlying the branching morphogenesis and patterning of the vascular and nervous systems.

MHI Seminar Series: Yosuke Mukoyama, Ph.D. Senior Investigator, Lab Stem Cell and Neurovascular Biology Cell and Developmental Biology Center, NHLBI/NHI, Bethesda, MD
2024-09-18 10:00 - 11:00 | Lineberger Comprehensive Cancer Center, Pagano Conference Room 00-002, 450 West Dr., Chapel Hill, NC, 27599, United States

2024 Triangle Regeneration Biology Symposium
2024-10-01 10:00 - 18:00 | Trent Semans Center, Duke University, 8 Searle Center Dr., Durham, NC, 27710, United States

MHI Special Seminar: Jaap van Buul, Ph.D., Professor, Vascular Cell Biology Lab, Amsterdam University Medical Center, Swammerdam Institute for Life Sciences, University of Amsterdam, The Netherlands
2024-10-07 14:30 - 15:30 | Lineberger Comprehensive Cancer Center, Pagano Conference Room 00-002, 450 West Dr., Chapel Hill, NC, 27599, United States

MHI Seminar Series: Stefania Nicoli, Ph.D., Associate Professor Tenure, MEDINT Cardiology, Yale University, New Haven, CT
2024-10-16 10:00 - 11:00 | Lineberger Comprehensive Cancer Center, Pagano Conference Room 00-002, 450 West Dr., Chapel Hill, NC, 27599, United States

MHI Seminar Series: Joshua D. Wythe, Ph.D., Associate Professor, Departments of Cell Biology & Neuroscience, University of Virginia School of Medicine
2024-11-13 10:00 - 11:00 | Lineberger Comprehensive Cancer Center, Pagano Conference Room 00-002, 450 West Dr., Chapel Hill, NC, 27599, United States

MHI Special Seminar: Francisco Laurindo, M.D., Ph.D., Professor & Director, Heart Institute Vascular Biology Lab, University of São Paolo, Brazil & President, Society for Redox Biology and Medicine
2024-11-19 12:30 - 13:30 | Marsico 2004, 125 Mason Farm Road, Chapel Hill, NC, 27514, United States

MHI Seminar Series: Jun Wang, Ph.D., Associate Professor, Departments of Pediatrics, The University of Texas Health Science Center at Houston
2024-12-04 10:00 - 11:00 | Lineberger Comprehensive Cancer Center, Pagano Conference Room 00-002, 450 West Dr., Chapel Hill, NC, 27599, United States

CANCELLED MHI Seminar Series: Karen Hirschi, Ph.D., Alumni Professor of Cell Biology, Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA
2025-02-11 09:33 | NC

2025 MHI/IVB Spring Research Symposium
2025-03-12 09:00 - 17:00 | The Carolina Club, George Watts Alumni Center, 150 Stadium Drive, Chapel Hill, NC, 27514

MHI Seminar Series: MHI Keynote Speaker -- Federica Accornero, Ph.D., Associate Professor, Molecular Biology, Cell Biology, and Biochemistry Brown University, Providence, RI
2025-03-12 15:00 - 16:00 | The Carolina Club, George Watts Alumni Center, 150 Stadium Drive, Chapel Hill, NC, 27514

MHI Seminar Series: Hanrui Zhang, Ph.D., Assistant Professor, Medicine/Cardiology, Columbia University, New York, NY
2025-03-26 10:00 - 11:00 | Bondurant Hall, Conference Room #G-100, 321 South Columbia St., Chapel Hill, NC, 27514, United States

MHI Special Seminar: Da-Zhi Wang, Ph.D., Professor, Internal Medicine and Molecular Pharmacology & Physiology; Endowed Chair of Cardiovascular Medicine; Director, Center for Regenerative Medicine, University of South Florida Health Heart Institute, Morsani College of Medicine, Tampa, FL
2025-03-28 10:00 - 11:00 | Marsico 2004, 125 Mason Farm Road, Chapel Hill, NC, 27514, United States

MHI Seminar Series: Michelle Ward, Ph.D., Assistant Professor, Biochemistry & Molecular Biology, The University of Texas Medical Branch at Galveston
2025-04-09 10:00 - 11:00 | Bondurant Hall, Conference Room #G-100, 321 South Columbia St., Chapel Hill, NC, 27514, United States
