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X-ORIGINAL-URL:https://www.med.unc.edu/mhi
X-WR-CALDESC:Events for UNC McAllister Heart Institute
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SUMMARY:MHI Seminar Series: Xander Wehrens\, MD\, PhD\, "Remodeling of calcium release unit proteins in Heart Failure"
DESCRIPTION:Speaker: Xander Wehrens\, MD\, PhD\, Professor\, Director of Cardiovascular Research Institute\, Baylor University\nTopic: “Remodeling of calcium release unit proteins in Heart Failure”
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-xander-wehrens-md-phd/
LOCATION:1131 Bioinformatics Building\, 130 Mason Farm Rd.\, Chapel Hill\, NC\, 27514\, United States
ORGANIZER;CN="Jimena Giudice":MAILTO:jimenagiudice@med.unc.edu
GEO:35.9036242;-79.0508779
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DTSTART;TZID=America/New_York:20180410T140000
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SUMMARY:MHI Seminar Series: Rong Tian\, MD\, PhD\, "Metabolic Modulation of Cardiac Remodeling"
DESCRIPTION:Speaker: Rong Tian\, MD\, PhD\, Professor of Anesthesiology and Pain Medicine\, Director of the Mitochondria and Metabolism Center\, University of Washington \nSeminar Title: “Metabolic Modulation of Cardiac Remodeling” \nMy research focuses on the molecular mechanisms regulating cell metabolism and energetics. A long-term goal of my laboratory is to understand the role of mitochondria and metabolism in the pathogenesis of human diseases\, in particular cardiovascular diseases. We have utilized molecular and genetic approaches to identify and perturb specific regulators in the key pathways of cardiac energy metabolism in mice and subsequently interrogated the physiological and biochemical responses in vivo during the development of heart failure using multi-nuclear NMR spectroscopy. Our work in the past two decades focused on the oxidative metabolism and mitochondrial ATP synthesis in heart failure using mouse models of altered glucose and fatty acid metabolism in the heart. Our recent work investigates the signaling role of cell metabolism through energy dependent and independent mechanisms. We also seek to decipher the mechanistic link between impaired mitochondrial function the cardiac stress responses. Results of these studies identified an important role of cellular redox state in diseases caused by mitochondrial dysfunction including cardiovascular and neurological pathologies. In collaboration with our clinical colleagues we are translating some of the research findings to clinical applications.
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-rong-tian-md-phd/
LOCATION:1131 Bioinformatics Building\, 130 Mason Farm Rd.\, Chapel Hill\, NC\, 27514\, United States
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DTSTART;TZID=America/New_York:20180424T110000
DTEND;TZID=America/New_York:20180424T120000
DTSTAMP:20260618T195312
CREATED:20180314T190617Z
LAST-MODIFIED:20180509T173455Z
UID:10000168-1524567600-1524571200@www.med.unc.edu
SUMMARY:MHI Seminar Series: Melina Kibbe\, MD\, "When Mice are Men: Sex Bias in Surgical Research"
DESCRIPTION:Speaker: Melina Kibbe\, MD\, Colin G. Thomas Jr. Distinguished Professor and Chair\, Department of Surgery\, UNC \nSeminar Title: “When Mice are Men: Sex Bias in Surgical Research” \nObjectives: \n\nTo explain the sex differences that exist with diseases processes.\nTo explain the sex disparity that exists in the development and evaluation of drugs\, devices\, and medical therapies.\nTo discuss the sex disparity that exists in biomedical and clinical research in surgery and other disciplines.\nTo present solutions that can improve sex inclusion in biomedical and clinical research\n\n 
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-speaker-melina-kibbe-md/
LOCATION:1131 Bioinformatics Building\, 130 Mason Farm Rd.\, Chapel Hill\, NC\, 27514\, United States
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