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X-WR-CALDESC:Events for UNC McAllister Heart Institute
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DTSTART;TZID=America/New_York:20180220T140000
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UID:10000157-1519135200-1519138800@www.med.unc.edu
SUMMARY:MHI Seminar Series: Deepak Voora\, MD\, “Genotype-informed Statin Therapy”
DESCRIPTION:Speaker: Dr. Deepak Voora\, MD\, Associate Professor of Medicine\, Department of Cardiology\, Center for Applied Genomics and Precision Medicine at Duke University\nTopic: “Genotype-informed Statin Therapy”\nSeminar Synopsis: Statins are among the most commonly prescribed medications to lower cholesterol and to prevent cardiovascular disease.  Although well tolerated by most patients\, a significant proportion of patients develop musculoskeletal symptoms associated with statin therapy that can lead to premature statin discontinuation\, elevated cholesterol\, and increased risk for cardiovascular events.  Our group was among the first to discover a reduced function genetic variant in the SLCO1B1 gene that predisposes to higher statin concentrations and statin-associated musculoskeletal symptoms (SAMS).  We have extended this finding to higher cholesterol levels in patients with cardiovascular disease treated with statins and tested for effects on cardiovascular events.   The statin-specific nature of SLCO1B1 associations with SAMS that we and others have identified laid the foundation to translate our findings into the clinic.  We have developed a genotype-informed statin therapy (GIST) intervention based on communicating SLCO1B1 genotype based risk for SAMS and tailored prescriptions to reduce the risk of SAMS.  In two prospective studies\, including a randomized clinical trial\, GIST improves perceptions of statin therapy\, increased statin re-initiation\, and lowered cholesterol levels in patients with statin-intolerance.
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-presents-dr-deepak-voora-md-genotype-informed-statin-therapy/
LOCATION:1131 Bioinformatics Building\, 130 Mason Farm Rd.\, Chapel Hill\, NC\, 27514\, United States
ORGANIZER;CN="Dr. Craig Lee":MAILTO:craig_lee@unc.edu
GEO:35.9036242;-79.0508779
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DTSTART;TZID=America/New_York:20180213T140000
DTEND;TZID=America/New_York:20180213T150000
DTSTAMP:20260405T072439
CREATED:20180209T185833Z
LAST-MODIFIED:20180209T190119Z
UID:10000155-1518530400-1518534000@www.med.unc.edu
SUMMARY:Christopher L. Holley\, MD\, PhD: “Non-coding RNA\, RNA modifications\, and Oxidative Stress in the Heart”
DESCRIPTION:
URL:https://www.med.unc.edu/mhi/event/christopher-l-holley-md-phd-non-coding-rna-rna-modifications-and-oxidative-stress-in-the-heart/
LOCATION:1131 Bioinformatics Building\, 130 Mason Farm Rd.\, Chapel Hill\, NC\, 27514\, United States
GEO:35.9036242;-79.0508779
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=1131 Bioinformatics Building 130 Mason Farm Rd. Chapel Hill NC 27514 United States;X-APPLE-RADIUS=500;X-TITLE=130 Mason Farm Rd.:geo:-79.0508779,35.9036242
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20171211T120000
DTEND;TZID=America/New_York:20171211T131000
DTSTAMP:20260405T072439
CREATED:20171201T182553Z
LAST-MODIFIED:20171201T182553Z
UID:10000154-1512993600-1512997800@www.med.unc.edu
SUMMARY:MHI Seminar Series Presents: Kristy Red-Horse\, Ph.D\, Stanford University
DESCRIPTION:
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-presents-kristy-red-horse-ph-d-stanford-university/
LOCATION:NC
ORGANIZER;CN="Tracy Riley":MAILTO:triley@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20171205T140000
DTEND;TZID=America/New_York:20171205T151000
DTSTAMP:20260405T072440
CREATED:20171201T182457Z
LAST-MODIFIED:20171201T182457Z
UID:10000153-1512482400-1512486600@www.med.unc.edu
SUMMARY:MHI Seminar Series Presents: Kristina I. Boström\, M.D.\, Ph.D.\, UCLA
DESCRIPTION:
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-presents-kristina-i-bostrom-m-d-ph-d-ucla/
LOCATION:NC
ORGANIZER;CN="Tracy Riley":MAILTO:triley@med.unc.edu
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