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X-ORIGINAL-URL:https://www.med.unc.edu/mhi
X-WR-CALDESC:Events for UNC McAllister Heart Institute
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DTSTART;TZID=America/New_York:20180313T090000
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SUMMARY:2018 MHI/IVB Research Symposium
DESCRIPTION:UNC’s Integrative Vascular Biology (IVB) Training Program and the McAllister Heart Institute (MHI) jointly announce their Annual Research Symposium on Tuesday\, March 13\, 2018. This year’s event will be held from 9AM – 5PM at the George Watts Hill Alumni Center on the UNC campus (150 Stadium Drive\, Chapel Hill\, NC 27514). The symposium highlights research from graduate students\, postdocs\, and medical fellows within the cardiovascular community at UNC and the greater Chapel Hill area and promotes multi-disciplinary collaborative research in this important field. This year’s keynote speakers will be Caroline and Geoffrey Burns (Harvard University) who will jointly present a talk entitled “New insights into zebrafish cardiovascular development and regeneration” and Karen Hirschi (Yale University) who will present a talk entitled “Regulation of endothelial cell specification”. \nAbstract submission –  For those who wish to present data at the symposium\, the abstract submission deadline is Monday\, February 26th. Abstracts should include a title and all authors and are limited to 250 words (not including the title\, etc). Note that you will need to have your abstract on hand during the registration process\, and please indicate whether you wish to be considered for a limited number of oral presentations. Poster board dimensions are 3ft high by 4ft wide. For more information please contact Hannah Perrin (hjperrin@email.unc.edu). \nThe registration deadline for those not presenting is March 8th.
URL:https://www.med.unc.edu/mhi/event/2018-mhiivb-research-symposium/
LOCATION:George Watts Alumni Center\, 150 Stadium Drive\, Chapel Hill\, NC
ORGANIZER;CN="Diane Berlin":MAILTO:berlindm@email.unc.edu
GEO:35.9069652;-79.0458004
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=George Watts Alumni Center 150 Stadium Drive Chapel Hill NC;X-APPLE-RADIUS=500;X-TITLE=150 Stadium Drive:geo:-79.0458004,35.9069652
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180306T140000
DTEND;TZID=America/New_York:20180306T150000
DTSTAMP:20260514T211516
CREATED:20180221T135407Z
LAST-MODIFIED:20180221T135407Z
UID:10000159-1520344800-1520348400@www.med.unc.edu
SUMMARY:MHI Seminar Series: James F. Martin\, MD\, PhD\, “Hippo Signaling in Heart Regeneration”
DESCRIPTION:Speaker: James F. Martin\, MD\, PhD\, Vivian L. Smith Professor in Regenerative Medicine\, Baylor College of Medicine; Director\, Cardiomyocyte Renewal Lab\, Texas Heart Institute\nTopic: “Hippo Signaling in Heart Regeneration” \nSeminar Synopsis: Dr. Martin is an internationally recognized developmental and regenerative biologist who has made fundamental contributions to our understanding of development\, disease\, and regeneration. He has authored more than 135 peer-reviewed papers in top journals such as Nature\, Science\, Cell\, Developmental Cell\, Plos Genetics\, Development\, and PNAS. His recent groundbreaking work on the Hippo pathway in heart size regulation is a landmark study that led to the insight that the Hippo pathway is an inhibitor of adult heart muscle regeneration. Dr. Martin’s insights revealed new avenues for treatment of human heart failure. Dr. Martin has made fundamental insights into the role of the transcription factor Pitx2 in atrial fibrillation\, the most common sustained arrhythmia in the human population. He made use of the mouse model to investigate Pitx2 in atrial homeostasis but also in left right asymmetric morphogenesis that is essential for human development. Dr. Martin’s studies investigating Pitx2 function in craniofacial development provided insight into the molecular basis of Rieger syndrome. He uncovered a pivotal function for Bmp signaling in endothelial-mesenchymal transition and cardiac valve development. Dr. Martin’s studies uncovered a novel role for canonical Wnt signaling in cardiac progenitor cell diversification. He found the first microRNA implicated in orofacial clefting. Dr. Martin’s studies are highly cited and also reported on by the lay media.
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-james-f-martin-md-phd-hippo-signaling-in-heart-regeneration/
LOCATION:1131 Bioinformatics Building\, 130 Mason Farm Rd.\, Chapel Hill\, NC\, 27514\, United States
ORGANIZER;CN="Dr. Frank Conlon":MAILTO:Frank_Conlon@med.unc.edu
GEO:35.9036242;-79.0508779
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180227T140000
DTEND;TZID=America/New_York:20180227T150000
DTSTAMP:20260514T211516
CREATED:20180215T195721Z
LAST-MODIFIED:20180221T135103Z
UID:10000158-1519740000-1519743600@www.med.unc.edu
SUMMARY:MHI Seminar Series: Douglas A. Marchuk\, PhD\, “Cerebral Cavernous Malformations: The Path from Gene Discovery to Therapy”
DESCRIPTION:Speaker: Dr. Douglas A. Marchuk\, PhD\, James B. Duke Professor\, Dept. of Molecular Genetics and Microbiology at Duke University\nTopic: “Cerebral Cavernous Malformations: The Path from Gene Discovery to Therapy”
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-presents-dr-douglas-a-marchuk-phd-cerebral-cavernous-malformations-the-path-from-gene-discovery-to-therapy/
LOCATION:NC
ORGANIZER;CN="Dr. Jonathan Schisler":MAILTO:schisler@unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180220T140000
DTEND;TZID=America/New_York:20180220T150000
DTSTAMP:20260514T211516
CREATED:20180215T195454Z
LAST-MODIFIED:20180221T135036Z
UID:10000157-1519135200-1519138800@www.med.unc.edu
SUMMARY:MHI Seminar Series: Deepak Voora\, MD\, “Genotype-informed Statin Therapy”
DESCRIPTION:Speaker: Dr. Deepak Voora\, MD\, Associate Professor of Medicine\, Department of Cardiology\, Center for Applied Genomics and Precision Medicine at Duke University\nTopic: “Genotype-informed Statin Therapy”\nSeminar Synopsis: Statins are among the most commonly prescribed medications to lower cholesterol and to prevent cardiovascular disease.  Although well tolerated by most patients\, a significant proportion of patients develop musculoskeletal symptoms associated with statin therapy that can lead to premature statin discontinuation\, elevated cholesterol\, and increased risk for cardiovascular events.  Our group was among the first to discover a reduced function genetic variant in the SLCO1B1 gene that predisposes to higher statin concentrations and statin-associated musculoskeletal symptoms (SAMS).  We have extended this finding to higher cholesterol levels in patients with cardiovascular disease treated with statins and tested for effects on cardiovascular events.   The statin-specific nature of SLCO1B1 associations with SAMS that we and others have identified laid the foundation to translate our findings into the clinic.  We have developed a genotype-informed statin therapy (GIST) intervention based on communicating SLCO1B1 genotype based risk for SAMS and tailored prescriptions to reduce the risk of SAMS.  In two prospective studies\, including a randomized clinical trial\, GIST improves perceptions of statin therapy\, increased statin re-initiation\, and lowered cholesterol levels in patients with statin-intolerance.
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-presents-dr-deepak-voora-md-genotype-informed-statin-therapy/
LOCATION:1131 Bioinformatics Building\, 130 Mason Farm Rd.\, Chapel Hill\, NC\, 27514\, United States
ORGANIZER;CN="Dr. Craig Lee":MAILTO:craig_lee@unc.edu
GEO:35.9036242;-79.0508779
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20180213T140000
DTEND;TZID=America/New_York:20180213T150000
DTSTAMP:20260514T211516
CREATED:20180209T185833Z
LAST-MODIFIED:20180209T190119Z
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SUMMARY:Christopher L. Holley\, MD\, PhD: “Non-coding RNA\, RNA modifications\, and Oxidative Stress in the Heart”
DESCRIPTION:
URL:https://www.med.unc.edu/mhi/event/christopher-l-holley-md-phd-non-coding-rna-rna-modifications-and-oxidative-stress-in-the-heart/
LOCATION:1131 Bioinformatics Building\, 130 Mason Farm Rd.\, Chapel Hill\, NC\, 27514\, United States
GEO:35.9036242;-79.0508779
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20171211T120000
DTEND;TZID=America/New_York:20171211T131000
DTSTAMP:20260514T211516
CREATED:20171201T182553Z
LAST-MODIFIED:20171201T182553Z
UID:10000154-1512993600-1512997800@www.med.unc.edu
SUMMARY:MHI Seminar Series Presents: Kristy Red-Horse\, Ph.D\, Stanford University
DESCRIPTION:
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-presents-kristy-red-horse-ph-d-stanford-university/
LOCATION:NC
ORGANIZER;CN="Tracy Riley":MAILTO:triley@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20171205T140000
DTEND;TZID=America/New_York:20171205T151000
DTSTAMP:20260514T211516
CREATED:20171201T182457Z
LAST-MODIFIED:20171201T182457Z
UID:10000153-1512482400-1512486600@www.med.unc.edu
SUMMARY:MHI Seminar Series Presents: Kristina I. Boström\, M.D.\, Ph.D.\, UCLA
DESCRIPTION:
URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-presents-kristina-i-bostrom-m-d-ph-d-ucla/
LOCATION:NC
ORGANIZER;CN="Tracy Riley":MAILTO:triley@med.unc.edu
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