Congratulations to the Lab of William Polacheck, Ph.D., an MHI member and Associate Professor of Biomedical Engineering; Member, Cell Biology and Physiology Curriculum, UNC Medicine; Member, Comparative Medicine Institute, NCSU, for publishing article, titled “Endothelial-Smooth Muscle Microgauges for Modeling Pulmonary Arterial Vasoregulation” in a special issue of Lab On A Chip on breakthrough technologies and applications in organ-on-a-chip.
These studies identified a new tool to measure contraction and relaxation of arterial smooth muscle cells. These pulmonary arterial smooth muscle microgauges (PA-SMUGs) are microfabricated and endothelialized to allow high-throughput and flow-dependent measurement of vasoconstriction and vasorelaxation. The work was featured in Issue 23, 2025 of the journal Lab On A Chip and can be read online now.