BEGIN:VCALENDAR VERSION:2.0 PRODID:-//UNC McAllister Heart Institute - ECPv6.15.18//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-ORIGINAL-URL:https://www.med.unc.edu/mhi X-WR-CALDESC:Events for UNC McAllister Heart Institute REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20170312T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20171105T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20180311T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20181104T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20190310T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20191103T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20200308T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20201101T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/New_York:20191204T100000 DTEND;TZID=America/New_York:20191204T110000 DTSTAMP:20260423T210300 CREATED:20191112T123730Z LAST-MODIFIED:20191112T123730Z UID:10000197-1575453600-1575457200@www.med.unc.edu SUMMARY:MHI Seminar Series: Ying Zheng\, Ph.D.\, “Organ-Specific Microvascular Engineering for Tissue Regeneration and Disease Modeling” DESCRIPTION: URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-ying-zheng-ph-d-organ-specific-microvascular-engineering-for-tissue-regeneration-and-disease-modeling/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States ORGANIZER;CN="Sherri Childs":MAILTO:sherrich@med.unc.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20191120T100000 DTEND;TZID=America/New_York:20191120T110000 DTSTAMP:20260423T210300 CREATED:20191025T134252Z LAST-MODIFIED:20191025T134252Z UID:10000198-1574244000-1574247600@www.med.unc.edu SUMMARY:MHI Seminar Series: Joy Lincoln\, Ph.D.\, “Developing mechanistic-based therapies in the treatment of calcific aortic valve disease” DESCRIPTION: URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-joy-lincoln-ph-d-developing-mechanistic-based-therapies-in-the-treatment-of-calcific-aortic-valve-disease/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States ORGANIZER;CN="Sherri Childs":MAILTO:sherrich@med.unc.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20191106T100000 DTEND;TZID=America/New_York:20191106T110000 DTSTAMP:20260423T210300 CREATED:20191024T174149Z LAST-MODIFIED:20191024T174149Z UID:10000199-1573034400-1573038000@www.med.unc.edu SUMMARY:MHI Seminar Series: David Kass\, M.D.\, “Leveraging Protein Kinase G to Treat Heart Disease” DESCRIPTION: URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-david-kass-m-d-leveraging-protein-kinase-g-to-treat-heart-disease/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States ORGANIZER;CN="Sherri Childs":MAILTO:sherrich@med.unc.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20191016T100000 DTEND;TZID=America/New_York:20191016T110000 DTSTAMP:20260423T210300 CREATED:20191001T204619Z LAST-MODIFIED:20191001T204619Z UID:10000183-1571220000-1571223600@www.med.unc.edu SUMMARY:MHI Seminar Series: Timothy A. McKinsey\, Ph.D.\, “Epigenetic Therapies for Heart Failure” DESCRIPTION: URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-timothy-a-mckinsey-ph-d-epigenetic-therapies-for-heart-failure/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States ORGANIZER;CN="Sherri Childs":MAILTO:sherrich@med.unc.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190925T100000 DTEND;TZID=America/New_York:20190925T110000 DTSTAMP:20260423T210300 CREATED:20190725T154958Z LAST-MODIFIED:20190802T173903Z UID:10000185-1569405600-1569409200@www.med.unc.edu SUMMARY:MHI Seminar Series: Yuqing E. Chen\, Ph.D.\, M.D.\, Advancing Lipid Gene Discoveries to Innovative Targets for Cardiovascular Disease DESCRIPTION: URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-yuqing-e-chen-ph-d-m-d-advancing-lipid-gene-discoveries-to-innovative-targets-for-cardiovascular-disease/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States ORGANIZER;CN="Sherri Childs":MAILTO:sherrich@med.unc.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190911T100000 DTEND;TZID=America/New_York:20190911T110000 DTSTAMP:20260423T210300 CREATED:20190725T154413Z LAST-MODIFIED:20190802T173934Z UID:10000186-1568196000-1568199600@www.med.unc.edu SUMMARY:MHI Seminar Series: Kathy K. Griendling\, PhD\, Poldip2\, Nox4 and Vascular Disease DESCRIPTION: URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-kathy-k-griendling-phd-poldip2-nox4-and-vascular-disease/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States ORGANIZER;CN="Sherri Childs":MAILTO:sherrich@med.unc.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190410T100000 DTEND;TZID=America/New_York:20190410T110000 DTSTAMP:20260423T210300 CREATED:20190404T171841Z LAST-MODIFIED:20190404T171841Z UID:10000187-1554890400-1554894000@www.med.unc.edu SUMMARY:MHI Seminar Series: Mugé N. Kuyumcu-Martinez\, Rbfox2 regulated alternative splicing networks modulate Hippo signaling during cardiovascular development DESCRIPTION: URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-muge-n-kuyumcu-martinez-rbfox2-regulated-alternative-splicing-networks-modulate-hippo-signaling-during-cardiovascular-development/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States ORGANIZER;CN="Sherri Childs":MAILTO:sherrich@med.unc.edu END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190403T100000 DTEND;TZID=America/New_York:20190403T110000 DTSTAMP:20260423T210300 CREATED:20190108T153906Z LAST-MODIFIED:20190326T180803Z UID:10000189-1554285600-1554289200@www.med.unc.edu SUMMARY:MHI Seminar Series: Christopher Hughes\, Ph.D DESCRIPTION:Speaker: Christopher Hughes\, Ph.D\, Professor & Chair\, Molecular Biology and Biochemistry\, University of California\, Irvine\nTopic: Tissue engineering of functional vascular networks for organ-on-chip applications \nBrief summary: The seminar will cover development of vascularized micro-organs (organ-on-chip technology)\, including brain\, liver and tumors\, and the potential for these in basic research\, drug development/validation and personalized medicine. URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-christopher-hughes-ph-d/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190320T100000 DTEND;TZID=America/New_York:20190320T110000 DTSTAMP:20260423T210300 CREATED:20190108T153747Z LAST-MODIFIED:20190306T194943Z UID:10000190-1553076000-1553079600@www.med.unc.edu SUMMARY:MHI Seminar Series: Joyce Bischoff\, Ph.D DESCRIPTION:Speaker: Joyce Bischoff\, Ph.D\, Professor\, Surgery/Vascular Biology Program\, Boston Children’s Hospital/Harvard Medical School\nTopic: Endothelial-to-Mesenchymal Transition in Mitral Valve Adaptation and Growth URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-joyce-bischoff-ph-d/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190306T100000 DTEND;TZID=America/New_York:20190306T110000 DTSTAMP:20260423T210300 CREATED:20190306T205138Z LAST-MODIFIED:20190306T205138Z UID:10000188-1551866400-1551870000@www.med.unc.edu SUMMARY:MHI Seminar Series: Mugé N. Kuyumcu-Martinez\, Ph.D DESCRIPTION:Speaker: Mugé N. Kuyumcu-Martinez\, Ph.D\, Associate Professor\, Dept. of Biochemistry & Molecular Biology\, Dept. of Neuroscience\, Cell Biology & Anatomy\, University of Texas Medical Branch\nTopic: Rbfox2 controls cardiovascular development via modulating Hippo signaling URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-muge-n-kuyumcu-martinez-ph-d/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190220T100000 DTEND;TZID=America/New_York:20190220T110000 DTSTAMP:20260423T210300 CREATED:20190108T153456Z LAST-MODIFIED:20190205T170648Z UID:10000173-1550656800-1550660400@www.med.unc.edu SUMMARY:MHI Seminar Series: Elizabeth Murphy\, Ph.D\, "Novel mechanisms of cardioprotection" DESCRIPTION:Speaker: Elizabeth Murphy\, Ph.D\, National Institutes of Health\nTopic: Novel mechanisms of cardioprotection \nSummary: \nIn the heart\, interruption of the blood supply can result in cardiac cell death and irreversible muscle damage. Dr. Murphy’s laboratory studies the molecular mechanisms involved in cardiac cell death\, as well as the mechanisms that protect the heart against damage. The knowledge gained from these studies may help identify novel therapies to reduce cardiac injury during ischemia and reperfusion. The current dogma suggests that calcium overload and reactive oxygen species generated during ischemia and heart failure lead to activation of a mitochondrial pore (mPTP) which initiates cell death. To better understand the regulation of the mPTP her lab has studied the mechanisms regulated by cyclophilin D\, the only currently established member (albeit a regulator) of the mPTP. These studies demonstrated that cyclophilin D regulates mitochondrial acetylation (Nguyen et al Circ. Res\, 2013). Collaborative studies with the Finkel laboratory leveraged recent advances identifying the mitochondrial transporter responsible for mitochondrial calcium uptake\, which allowed for mechanistic studies of the role of calcium in activating cell death (Pan et al Nat Cell Biol\, 2013). URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-elizabeth-murphy-ph-d/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190206T100000 DTEND;TZID=America/New_York:20190206T110000 DTSTAMP:20260423T210300 CREATED:20190108T153322Z LAST-MODIFIED:20190204T133231Z UID:10000174-1549447200-1549450800@www.med.unc.edu SUMMARY:MHI Seminar Series: Yoh-suke Mukouyama\, Ph.D DESCRIPTION:Speaker: Yoh-suke Mukouyama\, Ph.D\, National Institutes of Health\nTopic:Macrophage control of neuronal and vascular development \nBrief summary:  Macrophages have diverse functions in immunity as well as in homeostasis\, yet their functions during organ development remain largely undefined. Our work employs high-resolution whole-mount imaging and genetic tools to determine how embryonic tissue-resident macrophages influence neuronal and vascular development at single-cell resolution. URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-yoh-suke-mukouyama-ph-d/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190123T100000 DTEND;TZID=America/New_York:20190123T110000 DTSTAMP:20260423T210300 CREATED:20190108T153159Z LAST-MODIFIED:20190108T153159Z UID:10000175-1548237600-1548241200@www.med.unc.edu SUMMARY:MHI Seminar Series: Young-sup Yoon\, M.D.\, Ph.D DESCRIPTION:Speaker: Young-sup Yoon\, M.D.\, Ph.D\, Emory University URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-young-sup-yoon-m-d-ph-d/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20190109T100000 DTEND;TZID=America/New_York:20190109T110000 DTSTAMP:20260423T210300 CREATED:20190107T180316Z LAST-MODIFIED:20190107T180316Z UID:10000176-1547028000-1547031600@www.med.unc.edu SUMMARY:MHI Seminar Series: Dr. Robert Wirka DESCRIPTION:Speaker: Dr. Robert Wirka\, Stanford University. \nTopic: Single cell analysis of smooth muscle cell phenotypic modulation in vivo reveals a critical role for coronary disease gene TCF21 in mice and humans URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-dr-robert-wirka/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20181219T100000 DTEND;TZID=America/New_York:20181219T110000 DTSTAMP:20260423T210300 CREATED:20180803T185525Z LAST-MODIFIED:20180907T120417Z UID:10000163-1545213600-1545217200@www.med.unc.edu SUMMARY:MHI Seminar Series: Dr. Ann Murphy DESCRIPTION:Speaker: Dr. Ann Murphy\, Johns Hopkins University URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-dr-ann-murphy/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20181205T100000 DTEND;TZID=America/New_York:20181205T110000 DTSTAMP:20260423T210300 CREATED:20180803T185403Z LAST-MODIFIED:20180907T120334Z UID:10000164-1544004000-1544007600@www.med.unc.edu SUMMARY:MHI Seminar Series: Dr. Da-zhi Wang DESCRIPTION:Speaker: Dr. Da-zhi Wang\, Harvard University URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-dr-da-zhi-wang/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20181128T100000 DTEND;TZID=America/New_York:20181128T110000 DTSTAMP:20260423T210300 CREATED:20180907T115932Z LAST-MODIFIED:20180907T115932Z UID:10000177-1543399200-1543402800@www.med.unc.edu SUMMARY:MHI Seminar Series: Dr. Matthew C. Zimmerman DESCRIPTION:Speaker: Dr. Matthew C Zimmerman\, University of Nebraska Medical Center URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-dr-matthew-c-zimmerman/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20181107T100000 DTEND;TZID=America/New_York:20181107T110000 DTSTAMP:20260423T210300 CREATED:20180907T115502Z LAST-MODIFIED:20181023T133603Z UID:10000178-1541584800-1541588400@www.med.unc.edu SUMMARY:MHI Seminar Series: Dr Matthias Nahrendorf DESCRIPTION:Speaker: Dr. Matthias Nahrendorf\,  Professor\, Center for Systems Biology\, Harvard University\nTopic: Myeloid Cells in Cardiovascular Disease URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-dr-matthias-nahrendorf/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20181024T100000 DTEND;TZID=America/New_York:20181024T110000 DTSTAMP:20260423T210300 CREATED:20180907T114302Z LAST-MODIFIED:20180907T115108Z UID:10000179-1540375200-1540378800@www.med.unc.edu SUMMARY:MHI Seminar Series: Dr. Bill Polacheck DESCRIPTION: URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-dr-bill-polacheck/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20181012T100000 DTEND;TZID=America/New_York:20181012T110000 DTSTAMP:20260423T210300 CREATED:20180828T151718Z LAST-MODIFIED:20180907T115321Z UID:10000180-1539338400-1539342000@www.med.unc.edu SUMMARY:MHI Seminar Series: Dr. Lena Claesson-Walsh DESCRIPTION:Speaker: Dr. Lena Claesson-Walsh\, Uppsala University URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-dr-lena-claesson-walsh/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT BEGIN:VEVENT DTSTART;TZID=America/New_York:20180926T100000 DTEND;TZID=America/New_York:20180926T110000 DTSTAMP:20260423T210300 CREATED:20180803T185249Z LAST-MODIFIED:20180919T183957Z UID:10000165-1537956000-1537959600@www.med.unc.edu SUMMARY:MHI Seminar Series: Dr. Anne Marie Schmidt\, "Rage/Diaph1 Mechanism of Diabetic Complications and Metabolic Dysfunction" DESCRIPTION:Speaker: Dr. Anne Marie Schmidt\, New York University\nTopic: Rage/Diaph1 Mechanism of Diabetic Complications and Metabolic Dysfunction URL:https://www.med.unc.edu/mhi/event/mhi-seminar-series-dr-anne-marie-schmidt/ LOCATION:321 MacNider Hall\, 333 S Columbia St.\, Chapel Hill\, NC\, 27514\, United States END:VEVENT END:VCALENDAR