{"id":693,"date":"2026-05-06T13:06:48","date_gmt":"2026-05-06T17:06:48","guid":{"rendered":"https:\/\/www.med.unc.edu\/molecularmedicine\/?p=693"},"modified":"2026-05-08T15:51:19","modified_gmt":"2026-05-08T19:51:19","slug":"cmm-researchers-advance-human%e2%80%91based-models-to-improve-gene-therapy-safety","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/molecularmedicine\/2026\/05\/06\/cmm-researchers-advance-human%e2%80%91based-models-to-improve-gene-therapy-safety\/","title":{"rendered":"CMM Researchers Advance Human\u2011Based Models to Improve Gene Therapy Safety"},"content":{"rendered":"

CMM investigators Zhenwei Song, PhD,<\/a> and\u00a0Chengwen\u00a0(Chengwei) Li, MD, PhD,<\/a>\u00a0are developing a\u00a0human\u2011based\u00a03D liver model through a Triangle CERSI\u00a0NAMeRS\u00a0award<\/a> to better predict\u00a0gene\u2011therapy\u00a0toxicity, reduce reliance on animal testing, and accelerate safer therapeutic development.<\/p>\n

\"Zhenwei
Zhenwei Song, PhD and Chengwen Li, MD PhD<\/figcaption><\/figure>\n

Read a related article here: “CMM Faculty Contribute to New R01 Advancing Gene Therapy Safety.”<\/em><\/a><\/p>\n

<\/som-cell><\/div>\n

~ from UNC School of Pharmacy, “UNC Researchers Receive $2.9M Grant from NIH”<\/span><\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

CMM investigators Zhenwei Song, PhD, and Chengwen (Chengwei) Li, MD, PhD, are developing a human\u2011based 3D liver model through a Triangle CERSI NAMeRS award to better predict gene\u2011therapy toxicity, reduce reliance on animal testing, and accelerate safer therapeutic development.<\/p>\n","protected":false},"author":22429,"featured_media":583,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-693","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","odd"],"acf":[],"yoast_head":"\nCMM Researchers Advance Human\u2011Based Models to Improve Gene Therapy Safety - The Center for Molecular Medicine<\/title>\n<meta name=\"description\" content=\"CMM researchers, Zhengwei Song, PhD and Chengwen Li, MD 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