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6/12/09: Zylka and Philpot lab members earn awards

June 12, 2009

Congratulations to Sarah Street, a postdoc from the Zylka lab and Hsien Sung-Huang, a postdoc from the Philpot lab for each receiving a NC TraC$10K Pilot Program award.  17 awards were made out of 70 applicants.  These appear to be the only two labs from a basic science department to receive this award.  All other awardees are affiliated with clinical … Read more

5/01/09: Anton lab discovers new mechanism of tangential migration

May 4, 2009

In the article in PNAS, Eva Anton’s laboratory describes how specific guidance mechanisms involving netrin-integrin interactions modulate distinct routes of interneuronal migration and the consequent positioning of groups of cortical interneurons in the developing cerebral cortex. The emerging evidence for interneuronal subtype–specific dysfunction in a variety of neurodevelopmental disorders highlights the importance of understanding the … Read more

4/09/09: Polleux lab published paper in Neuron

April 8, 2009

Dante Bortone and Franck Polleux are the lead authors on the paper titled “KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner” that was published in Neuron. Proper development of cortical microcircuits requires the coordinated transition between neuronal migration and synaptogenesis for both excitatory pyramidal neuronsand inhibitory interneurons. The cellular and molecuar … Read more

2/01/09: UNC Neuroscience Center receives an Institutional Development Grant

February 1, 2009

Eva Anton is the PI of this grant The UNC Neuroscience Center received an Institutional Development Grant from the North Carolina Biotechnology Center to purchase an Olympus Fluoview FV1000-MPE multiphoton microscope for imaging the developing nervous system. Imaging the dynamics of neuronal development and differentiation in real time and in situ, at the systems, cellular, … Read more

11/17/08: Snider lab publishes article in PNAS

November 18, 2008

  A large multi-institutional collaboration, including Dr. William Snider’s laboratory, published an article in the Proceedings of the National Academy of Science which identifies a critical component in the development of human syndromes involving craniofacial and cardiac defects. This work began by characterizing patients with craniofacial and cardiac abnormalities akin to those seen in DiGeorge/Velocardiofacial Syndrome. Interestingly, … Read more

7/16/08: NIH grant will support neuroscience research core facilities

July 16, 2008

The UNC Neuroscience Center has been awarded a five-year, $3,650,000 Center Grant from the National Institute of Neurological Disorders and Stroke (NINDS). The Center Grant supports neuroscience research infrastructure by funding cutting edge core facilities. The six core areas that will be supported by this award are genomics and bioinformatics, gene expression localization, BAC (Bacterial … Read more

7/1/08: Deshmukh selected for Study Section Review

July 7, 2008

Congratulations to Mohanish Deshmukh who recently accepted an invitation to serve as a member of the International and Cooperative Projects 1 Study Section, Center for Scientific Review. His term will last from July 1, 2008 until June 30, 2012. This selection was based on Dr. Deshmukh’s achievements in his scientific discipline, and recognizes his successful … Read more

6/2/08: Polleux’s group publishes article in PLoS Biology

June 5, 2008

Dr Polleux’s group in the Neuroscience Center has recently published an article in the Public Access journal PLoS Biology (june 2008 issue) reporting the critical role of Netrin-1 signaling in the establishment of the topography of thalamocortical projections. The first author on this study is Ashton Powell (left), a student from the UNC Neurobiology Curriculum … Read more