BAC Recombineering Technology Core


Tang H, Ross A, Capel B. 2008. Expression and functional analysis of Gm114, a putative mammalian ortholog of Drosophila bam. Dev Biol. 318(1):73-81. PMCID: PMC2480617

Weimer JM, Stanco A, Cheng JG, Vargo AC, Voora S, Anton ES. 2008. A BAC transgenic mouse model to analyze the function of astroglial SPARCL1 (SC1) in the central nervous system. Glia. 56(9):935-41.


Bouvier J, Cheng JG. 2009. Recombineering-based procedure for creating Cre-LoxP conditional knockouts. Curr Protoc Mol Biol. Chapter 23:Unit 23.13.

Lazarenko RM, Milner TA, Depuy SD, Stornetta RL, West GH, Kievits JA, Bayliss DA, Guyenet PG. 2009. Acid-sensitivity and ultrastructure of the retrotrapezoid nucleus in a Phox2b-eGFP transgenic mouse. J Comp Neurol. 517(1):69-86. PMCID: PMC2826801

Pillai AM, Thaxton C, Pribisko AL, Cheng JG, Dupree JL, Bhat MA. 2009. Spatio-temporal Ablation of Myelinating Glia-Specific Neurofascin (NfascNF155) in Mice Reveals Gradual Loss of Paranodal Axo-Glial Junctions and Concomitant Disorganization of Axonal Domains. J Neurosci Res. 87(8):1773-93. PMCID: PMC2837286


Thaxton C, Pillai AM, Pribisko AL, Labasque M, Dupree JL, Faivre-Sarrailh C, Bhat MA. 2010. In Vivo Deletion of Immunoglobulin Domains 5 and 6 in Neurofascin (Nfasc) Reveals Domain-Specific Requirements in Myelinated Axons. J Neurosci. 30(14):4868-76. PMCID: PMC2856701


Buttermore ED, Dupree JL, Cheng J, An X, Tessarollo L, Bhat MA. 2011. The cytoskeletal adaptor protein band 4.1B is required for the maintenance of paranodal axoglial septate junctions in myelinated axons. J Neurosci. 31(22):8013-24. PMCID: PMC3121702

Eom TY, Stanco A, Weimer J, Stabingas K, Sibrack E, Gukassyan V, Cheng J, Anton ES. 2011. Direct visualization of microtubules using a genetic tool to analyze radial progenitor-astrocyte continuum in mice. Nat Commun. 2:446. doi: 10.1038/ncomms1460.

Hollenback SM, Lyman S, Cheng J. 2011. Recombineering-Based Procedure for Creating BAC Transgene Constructs for Animals and Cell Lines. Curr Protoc Mol Biol. Chapter 23:Unit 23.14. PMCID: PMC3141597

Newbern JM, Li X, Shoemaker SE, Zhou J, Zhong J, Wu Y, Bonder D, Hollenback S, Coppola G, Geschwind DH, Landreth GE, Snider WD. 2011. Specific functions for ERK/MAPK signaling during PNS development. Neuron. 69(1):91-105. PMCID: PMC3060558


Park JS, Ma W, O'Brien LL, Chung E, Guo JJ, Cheng JG, Valerius MT, McMahon J.A., Wong WH, McMahon AP 2012. Six2 and Wnt Regulate Self-Renewal and Commitment of Nephron Progenitors through Shared Gene Regulatory Networks. Dev Cell 23(3):637-51

McCoy, E.S., Taylor-Blake, B., Zylka, M.J. 2012. CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch. PloS ONE 2012;7(5):e36355

Cohen SP, Buckley BK, Kosloff M, Garland AL, Bosch DE, Cheng JG, Radhakrishna H, Brown MD, Willard FS, Arshavsky VY, Tarran R, Siderovski DP, Kimple AJ. (2012) Regulator of G-protein signaling-21 (RGS21) is an inhibitor of bitter gustatory signaling found in lingual and airway epithelia. J. Biol. Chem. 287(50):41706-19

Xiaoyan Li, Jason M. Newbern, Yaohong Wu, Meghan Morgan-Smith, Jian Zhong, Jean Charron, William D. Snider. MEK Is a Key Regulator of Gliogenesis in the Developing Brain. Neuron 2012 Sep 20; 75 (6): 1035-50

In situ Hybridization Core


Powell AW, Sassa T, Wu Y, Tessier-Lavigne M, Polleux F. Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon. PLoS Biol. 2008 May;6:1047-68.

Weimer JM, Stanco A, Cheng JG, Vargo AC, Voora S, Anton ES. A BAC transgenic mouse model to analyze the function of astroglial SPARCL1 (SC1) in the central nervous system. Glia. 2008 Jul;56:935-41.

Tucker ES, Segall S, Gopalakrishna D, Wu Y, Vernon M, Polleux F, Lamantia AS. Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminences. J Neurosci. 2008 Sep;28:9504-18.

Maynard TM, Meechan DW, Dudevoir ML, Gopalakrishna D, Peters AZ, Heindel CC, Sugimoto TJ, Wu Y, Lieberman JA, Lamantia AS. Mitochondrial localization and function of a subset of 22q11 deletion syndrome candidate genes. Mol Cell Neurosci. 2008 Nov;39:439-51.


James JM, Gewolb C, Bautch VL. Neurovascular development uses VEGF-A signaling to regulate blood vessel ingression into the neural tube. Development. 2009 Mar;136:833-41.

Meechan DW, Tucker ES, Maynard TM, LaMantia AS. Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome. Proc Natl Acad Sci U S A. 2009 Sep;106:16434-45.

Kim WY, Wang X, Wu Y, Doble BW, Patel S, Woodgett JR, Snider WD. GSK-3 is a master regulator of neural progenitor homeostasis. Nat Neurosci. 2009 Nov;12:1390-7.

Mona Buhusi, Galina P. Demyanenko, Karry M. Jannie, Jasbir Dalal, Eli P. B. Darnell,1 Joshua A. Weiner, and Patricia F. Maness. ALCAM Regulates Mediolateral Retinotopic Mapping in the Superior Colliculus The Journal of Neuroscience, December, 2009 29:15630 –15641


Manzini MC, Rajab A, Maynard TM, Mochida GH, Tan WH, Nasir R, Hill RS, Gleason D, Al Saffar M, Partlow JN, Barry BJ, Vernon M, LaMantia AS, Walsh CA. Developmental and degenerative features in a complicated spastic paraplegia. Ann Neurol. 2010 Apr;67(4):516-25.

Tucker ES, Lehtinen MK, Maynard T, Zirlinger M, Dulac C, Rawson N, Pevny L, Lamantia AS. Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium. Development. 2010 Aug 1;137(15):2471-81.

Yu TW, Mochida GH, Tischfield DJ, Sgaier SK, Flores-Sarnat L, Sergi CM, Topçu M, McDonald MT, Barry BJ, Felie JM, Sunu C, Dobyns WB, Folkerth RD, Barkovich AJ, Walsh CA. Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture. Nature Genetics. 2010 Nov;42(11):1015-20.


Demyanenko GP, Riday TT, Tran TS, Dalal J, Darnell EP, Brennaman LH, Sakurai T, Grumet M, Philpot BD, Maness PF. NrCAM deletion causes topographic mistargeting of thalamocortical axons to the visual cortex and disrupts visual acuity. J Neurosci. 2011 Jan 26;31(4):1545-58.

Matsushima, D., Heavner, W., Sowa, N., Futtner, C., Fagan, B.M. and Pevny, L.H. Combinatorial control of retinal cell fate by SOX2 and PAX6. Development. 2011 Feb:138, 443-454

D.W. Meechan, T.M. Maynard, E.S. Tucker1, A.-S. LaMantia. Three phases of DiGeorge/22q11 deletion syndrome pathogenesis during brain development: Patterning, proliferation, and mitochondrial functions of 22q11 genes. International Journal of Developmental Neuroscience. Volume 29, Issue 3, May 2011, Pages 283–294

Hartmann JS, Thompson H, Wang H, Kanekar S, Huang W, Budd SJ, Hartnett ME. Expression of vascular endothelial growth factor and pigment epithelial-derived factor in a rat model of retinopathy of prematurity. Mol Vis. 2011;17:1577-87.

Duan J, Gherghe C, Liu D, Hamlett E, Srikantha L, Rodgers L, Regan JN, Rojas M, Willis M, Leask A, Majesky M, Deb A. Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. EMBO J. 2011 Nov 15;31(2):429-42


Brennaman LH, Zhang X, Guan H, Triplett JW, Brown A, Demyanenko GP, Manis PB, Landmesser L, Maness PF. Polysialylated NCAM and EphrinA/EphA Regulate Synaptic Development of GABAergic Interneurons in Prefrontal Cortex. Cereb Cortex. 2012 Jan 23.

Langer L, Taranova O, Sulik K, Pevny L. SOX2 hypomorphism disrupts development of the prechordal floor and optic cup. Mech Dev. 2012 Mar-Jun;129(1-4):1-12.

Cattaneo ER, Pellon-Maison M, Rabassa ME, Lacunza E, Coleman RA, Gonzalez-Baro MR. Glycerol-3-phosphate acyltransferase-2 is expressed in spermatic germ cells and incorporates arachidonic Acid into triacylglycerols. PLoS One. 2012;7(8):e42986. Epub 2012 Aug 8.

Manzini MC, Tambunan DE, Hill RS, Yu TW, Maynard TM, Heinzen EL, Shianna KV, Stevens CR, Partlow JN, Barry BJ, Rodriguez J, Gupta VA, Al-Qudah AK, Eyaid WM, Friedman JM, Salih MA, Clark R, Moroni I, Mora M, Beggs AH, Gabriel SB, Walsh CA. Exome Sequencing and Functional Validation in Zebrafish Identify GTDC2 Mutations as a Cause of Walker-Warburg Syndrome. Am J Hum Genet. 2012 Sep 7; 91(3):541-7.

Xiaoyan Li, Jason M. Newbern, Yaohong Wu, Meghan Morgan-Smith, Jian Zhong, Jean Charron, William D. Snider. MEK Is a Key Regulator of Gliogenesis in the Developing Brain. Neuron 2012 Sep 20; 75 (6): 1035-50