Associate Professor & co-Director of Graduate Studies
\nUNC-Chapel Hill<\/p>\n
Michigan State University, BS, 2002
\nUniversity of Michigan, Ann Arbor, PhD, 2009
\nUniversity of Michigan, Ann Arbor, Postdoctoral, 2009-2011
\nUniversity of Michigan, Ann Arbor, Research Investigator, 2011-2014<\/p>\n
My laboratory investigates the regulation and function of disease-linked proteins, with a specific focus on post-translational modifications (PTMs). PTMs involve biochemical reactions that alter the structure, function, interactions, localization, and abundance of cellular proteins. During homeostasis, PTMs, such as phosphorylation and glycosylation, enable cells to respond to stimuli and adapt to changing conditions. In disease states, altered expression or activity of PTM on\/off enzymes, leads to aberrant protein regulation. Therefore, understanding PTM mechanisms can yield novel therapeutic targets and markers of disease activity. We pursue translational projects in this space, with an emphasis on two specific areas: (i) Regulation and function of the enzyme CD73 in liver homeostasis, chronic injury, and cancer and (ii) Regulation and function of glial intermediate filaments in pediatric neurodegenerative diseases.<\/p>\n
Postdoctoral Translational Scholars Program Award, University of Michigan, 2009-2011<\/i><\/p>\n
NIH K01 Mentored Research Scientist Development Award, 2011-2016<\/p>\n
Research Recognition Award \u2013 APS Gastrointestinal & Liver Physiology Section, 2012<\/p>\n
NIH R03 Small Research Grant Program, 2014-2016<\/p>\n
Curriculum in Cell Biology and Physiology<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"
Associate Professor & co-Director of Graduate Studies UNC-Chapel Hill Education and Training Michigan State University, BS, 2002 University of Michigan, Ann Arbor, PhD, 2009 University of Michigan, Ann Arbor, Postdoctoral, 2009-2011 University of Michigan, Ann Arbor, Research Investigator, 2011-2014 Areas of Interest My laboratory investigates the regulation and function of disease-linked proteins, with a specific … Read more<\/a><\/p>\n","protected":false},"featured_media":6824,"template":"","meta":{"_acf_changed":false,"_links_to":"","_links_to_target":""},"class_list":["post-6822","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"_upd_display_name":["Natasha Snider, PhD"],"_upd_reverse_display_name":["Snider, Natasha"],"_upd_last_name":["Snider"],"_upd_first_name":["Natasha"],"_upd_sortorder_override":[],"_upd_sortorder":["1"],"_upd_gallery_summary":["Associate Professor & co-Director of Graduate Studies\r\n<\/b>Office: MBRB 5340C\r\nBio<\/a> | <\/a>Email<\/a><\/span>"],"_upd_no_link":[],"_upd_degree1":["PhD"],"_upd_degree2":[],"_upd_email":[[{"email_text":"natasha_snider@med.unc.edu"}]],"_upd_phone":[[{"phone_text":"(919) 962-6033"}]],"_upd_address":[[{"address":{"address-1":"5340C MBRB","address-2":"","campus-box":"Campus Box 7545","city":"CHapel Hill","state":"NC","zip":"27599-7545"}}]],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/neuroscience\/curriculum\/wp-json\/wp\/v2\/directory\/6822","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/neuroscience\/curriculum\/wp-json\/wp\/v2\/directory"}],"about":[{"href":"https:\/\/www.med.unc.edu\/neuroscience\/curriculum\/wp-json\/wp\/v2\/types\/directory"}],"version-history":[{"count":1,"href":"https:\/\/www.med.unc.edu\/neuroscience\/curriculum\/wp-json\/wp\/v2\/directory\/6822\/revisions"}],"predecessor-version":[{"id":6823,"href":"https:\/\/www.med.unc.edu\/neuroscience\/curriculum\/wp-json\/wp\/v2\/directory\/6822\/revisions\/6823"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/neuroscience\/curriculum\/wp-json\/wp\/v2\/media\/6824"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/neuroscience\/curriculum\/wp-json\/wp\/v2\/media?parent=6822"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}