{"id":2874,"date":"2015-11-16T20:15:00","date_gmt":"2015-11-17T01:15:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/neuroscience\/bryan-roth-describes-a-new-tool-to-probe-the-activity-of-orphan-receptors-in-the-brain-in-the-journal-nature\/"},"modified":"2018-07-05T14:09:26","modified_gmt":"2018-07-05T18:09:26","slug":"bryan-roth-describes-a-new-tool-to-probe-the-activity-of-orphan-receptors-in-the-brain-in-the-journal-nature","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/neuroscience\/bryan-roth-describes-a-new-tool-to-probe-the-activity-of-orphan-receptors-in-the-brain-in-the-journal-nature\/","title":{"rendered":"Bryan Roth describes a new tool to probe the activity of orphan receptors in the brain in the journal Nature"},"content":{"rendered":"
\n

<\/p>\n

In an article published in Nature, Bryan Roth describes a new tool to probe the activity of orphan receptors, illuminating their roles in behavior and making them accessible for drug discovery.<\/p>\n

\n
\"image2\"
Bryan L Roth, MD, PhD<\/figcaption><\/figure>\n<\/div>\n
\n
Bryan Roth\u2019s lab has partnered with scientists at the University of California, San Francisco to create a general tool to probe the activity of orphan receptors, illuminating their roles in behavior and making them accessible for drug discovery. The creation of the research tool \u2013 which involves computer modeling, yeast- and mammalian cell-based molecular screening techniques, and mouse models \u2014 was published in the journal Nature<\/i><\/a>.<\/div>\n
According to Xi-Ping Huang, PhD, first author and research assistant professor at UNC, this work will help researchers learn how orphan receptors interact with molecules inside the body or with drugs. \u201cOrphan receptors could be a great source of therapeutics,\u201d Huang said. \u201cBut it has been difficult to study them. The research community has needed an approach that works, and that\u2019s why we put so much effort into this.\u201d<\/div>\n
For more information, visit the UNC School of Medicine Newsroom<\/a>.<\/i><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

<\/p>\n

In an article published in Nature, Bryan Roth describes a new tool to probe the activity of orphan receptors, illuminating their roles in behavior and making them accessible for drug discovery.<\/p>\n","protected":false},"author":40519,"featured_media":2875,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-2874","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"\nBryan Roth describes a new tool to probe the activity of orphan receptors in the brain in the journal Nature | UNC Neuroscience Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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