{"id":3108,"date":"2016-08-24T20:08:19","date_gmt":"2016-08-25T00:08:19","guid":{"rendered":"https:\/\/www.med.unc.edu\/neuroscience\/kash-lab-publishes-in-nature\/"},"modified":"2018-07-05T14:00:26","modified_gmt":"2018-07-05T18:00:26","slug":"kash-lab-publishes-in-nature","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/neuroscience\/kash-lab-publishes-in-nature\/","title":{"rendered":"Kash Lab Publishes in Nature"},"content":{"rendered":"
\n

<\/p>\n

UNC School of Medicine researchers map the anxiety circuit in the brain and use a compound to limit fearful behavior \u2013 an acute side effect of commonly prescribed SSRI antidepressants.<\/p>\n

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\"image2\"
Thomas Kash, PhD<\/figcaption><\/figure>\n<\/div>\n
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The new study, published in Nature<\/a><\/i>, counters the popular view of serotonin as a neurotransmitter that promotes only good feelings. SSRIs, which are taken by about one in 10 people in the United States and about one in four women in their 40s and 50s, are thought to improve mood by boosting serotonin activity in the brain. There are brain circuits through which serotonin does seem to improve mood, and some studies have linked depression to abnormally low levels of serotonin. But the short-lived promotion of anxiety in many patients on SSRIs \u2013 even suicidal thinking, particularly in younger people \u2013 has long hinted that serotonin can have negative effects on mood, depending on the precise brain circuit where it acts.<\/p>\n

For more information, visit the UNC News Room<\/a>.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

<\/p>\n

UNC School of Medicine researchers map the anxiety circuit in the brain and use a compound to limit fearful behavior \u2013 an acute side effect of commonly prescribed SSRI antidepressants.<\/p>\n","protected":false},"author":70069,"featured_media":3109,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-3108","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"\nKash Lab Publishes in Nature | UNC Neuroscience Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/neuroscience\/kash-lab-publishes-in-nature\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" 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